Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Marla C, Dubinsky"'
Autor:
Elizabeth A. Spencer, Marla C. Dubinsky, Michael A. Kamm, Maria Chaparro, Paolo Gionchetti, Fernando Rizzello, Javier P. Gisbert, Emily K. Wright, Julien D. Schulberg, Amy L. Hamilton, Dermot P. B. McGovern, Thierry Dervieux
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4fd9de70c804409e9437ad5e101a7db8
Autor:
Ishaan Dharia, Taqwa Ahmed, Michael Plietz, Sergey Khaitov, Patricia Sylla, Alexander Greenstein, Marla C. Dubinsky, Maia Kayal
Publikováno v:
Inflammatory Intestinal Diseases, Pp 1-4 (2023)
Background: Micronutrient deficiencies may occur after restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) in patients with ulcerative colitis (UC), largely due to malabsorption and/or pouch inflammation. Objectives: The object
Externí odkaz:
https://doaj.org/article/28fb9687175e4f29bb9bf003b2293091
Autor:
Elizabeth A. Spencer, Marla C. Dubinsky, Michael A. Kamm, Maria Chaparro, Paolo Gionchetti, Fernando Rizzello, Javier P. Gisbert, Emily K. Wright, Julien D. Schulberg, Amy L. Hamilton, Dermot P. B. McGovern, Thierry Dervieux
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe evaluated baseline Clearance of anti-tumor necrosis factors and human leukocyte antigen variant (HLA DQA1*05) in combination as poor prognostic factors (PPF) of pharmacokinetic (PK) origin impacting immune response (formation of antidr
Externí odkaz:
https://doaj.org/article/22a1d851031241dcae3bcd681f13b292
Autor:
Brian G Feagan, Toshifumi Hibi, Vipul Jairath, Nathan Morris, Bruce E Sands, Marla C Dubinsky, Vipin Arora, April N Naegeli, Trevor Lissoos, Mingyang Shan, Jay Tuttle, Noah Agada
Publikováno v:
BMJ Open Gastroenterology, Vol 10, Iss 1 (2023)
Objective Mirikizumab, a monoclonal antibody targeting the interleukin-23 p19 subunit, was effective in a Phase 2 study (NCT02589665) of moderately-to-severely active ulcerative colitis (UC). We studied mirikizumab’s impact on health-related qualit
Externí odkaz:
https://doaj.org/article/d32d694829724ced8385109aced67187
Autor:
Marla C. Dubinsky, Mingyang Shan, Laure Delbecque, Trevor Lissoos, Theresa Hunter, Gale Harding, Larissa Stassek, David Andrae, James D. Lewis
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 6, Iss 1, Pp 1-15 (2022)
Abstract Background The Urgency Numeric Rating Scale (NRS) was developed as a content-valid single-item patient-reported outcome measure to assess severity of bowel urgency. Here, we evaluated the psychometric properties of the Urgency NRS. Methods D
Externí odkaz:
https://doaj.org/article/c6a53c14aaa4456ebbad9e13ff396443
Autor:
Marla C. Dubinsky, Peter M. Irving, Remo Panaccione, April N. Naegeli, Alison Potts-Bleakman, Vipin Arora, Mingyang Shan, Simon Travis
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 6, Iss 1, Pp 1-11 (2022)
Abstract Background Bowel urgency, the sudden or immediate need to have a bowel movement, is a common, bothersome and disruptive symptom of ulcerative colitis (UC). UC treatment goals include control of urgency; however, it is not consistently assess
Externí odkaz:
https://doaj.org/article/c7fd842e48c741bdbd35587dbd19052e
Autor:
Benjamin Click, Edward L. Barnes, Benjamin L. Cohen, Bruce E. Sands, John S. Hanson, David T. Rubin, Marla C. Dubinsky, Miguel Regueiro, Derek Gazis, Julie M. Crawford, Millie D. Long
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Inflammatory bowel disease (IBD) treatment paradigms recommend objective disease activity assessment and reactive therapeutic drug monitoring (TDM) prior to changes in biologic therapy. We aimed to describe objective marker and TD
Externí odkaz:
https://doaj.org/article/c94a6d498f654c49b59bc62a2e6ffb57
Autor:
Marla C. Dubinsky, Shervin Rabizadeh, John C. Panetta, Elizabeth A. Spencer, Annelie Everts-van der Wind, Thierry Dervieux
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2408 (2023)
Infliximab (IFX) concentrations are a predictive factor (PF) of pharmacokinetic (PK) origin in the treatment of Crohn’s disease (CD). We evaluated Clearance, another PF of PK origin, either alone or in combination with concentrations. They were eva
Externí odkaz:
https://doaj.org/article/dea09ccc678a456c878679f1158b2931
Autor:
Graham J. Britton, Alice Chen-Liaw, Francesca Cossarini, Alexandra E. Livanos, Matthew P. Spindler, Tamar Plitt, Joseph Eggers, Ilaria Mogno, Ana S. Gonzalez-Reiche, Sophia Siu, Michael Tankelevich, Lauren Tal Grinspan, Rebekah E. Dixon, Divya Jha, Adriana van de Guchte, Zenab Khan, Gustavo Martinez-Delgado, Fatima Amanat, Daisy A. Hoagland, Benjamin R. tenOever, Marla C. Dubinsky, Miriam Merad, Harm van Bakel, Florian Krammer, Gerold Bongers, Saurabh Mehandru, Jeremiah J. Faith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from infected individuals. In lieu of
Externí odkaz:
https://doaj.org/article/d6c31edc6052419cbb41e75506d8cb06
Autor:
Maia Kayal, Marla C. Dubinsky
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100095- (2022)
Externí odkaz:
https://doaj.org/article/6434207f307e469b9935a5d4d839ff43