Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Marlène Dubuisson"'
Autor:
Marlène Dubuisson, Bertrand de Wergifosse, Jacqueline Marchand-Brynaert, Jean-François Rees, André Trouet
Publikováno v:
Free Radical Biology and Medicine. 36:278-287
Coelenterazine is a luciferin found in many marine bioluminescent organisms. This luciferin also possesses high antioxidant properties and an exceptional ability to protect cells exposed to oxidative stress. It has been suggested that coelenterazine'
Autor:
Alex Cordi, Jacqueline Marchand-Brynaert, Marlène Dubuisson, Tony Verbeuren, Cécile Marchand, Axelle Arrault, Sonia Gharbi, Eliete Bouskela, Jean-François Rees, Alain Rupin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:653-656
A series of 2-substituted 3,7-dihydroimidazolo[1,2-a]pyrazine-3-ones has been synthesized and evaluated for their antioxidant activity. Compounds 1-8 are inhibitors of AAPH-induced lipid peroxidation (in vitro) and excellent protectors against microv
Autor:
B de Wergifosse, André Trouet, Marlène Dubuisson, Fernand Baguet, Jacqueline Marchand-Brynaert, Jean-François Rees
Publikováno v:
Biochemical Pharmacology. 60:471-478
Coelenterazine (CLZn; 3, 7-dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo++ +[1 ,2-a]pyrazin-3-one), the substrate for bioluminescence reactions in many marine animals, is endowed with high antioxidant properties. This work investi
Autor:
Pierre Morsomme, Bernard Knoops, Hervé Degand, Franck Zal, Jean-François Rees, Marlène Dubuisson, André Clippe, Eléonore Loumaye, Ann C. Andersen
Publikováno v:
Free radical biologymedicine. 45(4)
Peroxiredoxins (PRDXs) are a superfamily of thiol-dependent peroxidases found in all phyla. PRDXs are mechanistically divided into three subfamilies, namely typical 2-Cys, atypical 2-Cys, and 1-Cys PRDXs. To reduce peroxides, the N-terminal peroxidat
Publikováno v:
Drug development and industrial pharmacy. 31(9)
Coelenterazine and derivatives were initially considered in the scientific community for their (bio)luminescent properties. Now, another interest of such hetero-bicycles has been pointed out by the discovery of remarkable antioxidative properties, an
Publikováno v:
Luminescence : the journal of biological and chemical luminescence. 19(6)
Insects are the main group with luminescent species among terrestrial animals. In this paper, we report that fire fly luciferin is endowed with antioxidant properties against oxidative and nitrosative stress. The luciferin reduces linoleate peroxidat
Publikováno v:
Mini Reviews in Medicinal Chemistry. 4
Coelenteramine (2-amino-1,4-pyrazine derivative), one of the metabolites of the oxidative degradation of coelenterazine (imidazolopyrazinone derivative), is endowed with excellent antioxidative properties towards ROS/RNS, like its mother-compound. Th
Autor:
Willem H. Koppenol, Jean-François Rees, Reinhard Kissner, Thomas Nauser, Marlène Dubuisson, Bernard Knoops, André Clippe, Delphine Vander Stricht, Florence Etienne
Publikováno v:
FEBS Letters. (1-3):161-165
Peroxiredoxins are an ubiquitous family of peroxidases widely distributed among prokaryotes and eukaryotes. Peroxiredoxin 5, which is the last discovered mammalian member, was previously shown to reduce peroxides with the use of reducing equivalents
Autor:
B. Janssens, O. Noiset, Jean-François Rees, Marlène Dubuisson, B de Wergifosse, Eric M. Thompson
Publikováno v:
Scopus-Elsevier
Journal of Experimental Biology
Journal of Experimental Biology, The Company of Biologists, 1998, 201, pp.1211-1221
Journal of Experimental Biology
Journal of Experimental Biology, The Company of Biologists, 1998, 201, pp.1211-1221
Bioluminescence, the emission of ecologically functional light by living organisms, emerged independently on several occasions, yet the evolutionary origins of most bioluminescent systems remain obscure. We propose that the luminescent substrates of
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