Aurora B Kinase and Passenger Proteins as Targets for Cancer Therapy

Autor: Marlène Delacour-Larose, Thi My Nhung Hoang, Annie Molla

Publikováno v: Current Enzyme Inhibition. 4:153-159

The chromosome passenger complex (CPC) is composed of five proteins: Aurora B kinase, Borealin, INCENP, Survivin and TD-60. CPC functions as an oligo-enzyme, each member activating the catalytic subunit, Aurora B kinase. CPC controls chromosome congr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52d4bc828471bf279d668e1e60ec8907
https://doi.org/10.2174/157340808785909402

Aurora B kinase, an immobile passenger!

Autor: Marlène Delacour-Larose, Hong-Lien Vu, Annie Molla

Publikováno v: Cell cycle (Georgetown, Tex.). 8(21)

The chromosomal passenger complex (CPC) is a key mitotic regulator composed of Aurora B kinase, Survivin, Borealin and INCENP.[1]The centromeric complex is involved in the correction of mis-attached microtubules by sensing tension on kinetochores. Au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac57b50ea16642202dfd593d0aababd
https://pubmed.ncbi.nlm.nih.gov/19838060

How Elementary Mercury Reacts in the Presence of Halogen Radicals and/or Halogen Anions: A DFT Investigation

Autor: Christophe Ferrari, Laurent Maron, Marlène Delacour-Larose, Aurélien Dommergue, Xavier Faïn

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2008, 14 (27), pp.8322 à 8329. ⟨10.1002/chem.200800491⟩
Chemistry-A European Journal, 2008, 14 (27), pp.8322 à 8329. ⟨10.1002/chem.200800491⟩

International audience; Reactions of elementary mercury in the gas phase (GEM) have been investigated at the DFT level in the presence of halogen radicals and/or halogen anions. In the presence of radicals, the formation of HgX3. and HgX42. is predic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe603f98a95fdb505be468eb02f5fc7f
https://hal-insu.archives-ouvertes.fr/insu-00379686

Dissection of the unusual structural and functional properties of the variant H2A.Bbd nucleosome

Autor: Marlène Delacour-Larose, Thierry Gautier, Cécile Marie Doyen, Dimitri Angelov, Philippe Bouvet, Jan Bednar, Ali Hamiche, Hervé Menoni, Cyril Claudet, Stefan Dimitrov, Fabien Montel, Cendrine Faivre-Moskalenko

Publikováno v: EMBO Journal
EMBO Journal, 2006, 25 (18), pp.4234-44. ⟨10.1038/sj.emboj.7601310⟩
EMBO Journal, EMBO Press, 2006, 25 (18), pp.4234-44. ⟨10.1038/sj.emboj.7601310⟩

International audience; The histone variant H2A.Bbd appeared to be associated with active chromatin, but how it functions is unknown. We have dissected the properties of nucleosome containing H2A.Bbd. Atomic force microscopy (AFM) and electron cryo-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0ca19c20b73c766898e3e11c2c2b6c
https://www.hal.inserm.fr/inserm-00335077/document