Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Marlène, Debiossat"'
1
Akademický článek
A single-domain antibody for the detection of pathological Tau protein in the early stages of oligomerization
Autor: Nicolas De Leiris, Pascale Perret, Charlotte Lombardi, Bülent Gözel, Sabine Chierici, Philippe Millet, Marlène Debiossat, Sandrine Bacot, Benjamin B. Tournier, Patrick Chames, Jean-Luc Lenormand, Catherine Ghezzi, Daniel Fagret, Marcelle Moulin
Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Soluble oligomeric forms of Tau protein have emerged as crucial players in the propagation of Tau pathology in Alzheimer’s disease (AD). Our objective is to introduce a single-domain antibody (sdAb) named 2C5 as a novel radiotra
Externí odkaz: https://doaj.org/article/1ac0048706c44dee9da004630017f449
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2
Akademický článek
TrisOxine abiotic siderophores for technetium complexation: radiolabeling and biodistribution studies
Autor: Julien Leenhardt, Alexandre Biguet Petit Jean, Florian Raes, Emilien N’Guessan, Marlène Debiossat, Clémence André, Sandrine Bacot, Mitra Ahmadi, Nicolas de Leiris, Loïc Djaileb, Catherine Ghezzi, Marie-Dominique Brunet, Alexis Broisat, Pascale Perret, Amaury du Moulinet d’Hardemare
Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-19 (2023)
Abstract Background Despite the development of positron emission tomography (PET), single photon emission computed tomography (SPECT) still accounts for around 80% of all examinations performed in nuclear medicine departments. The search for new radi
Externí odkaz: https://doaj.org/article/29b0c4ea072a4535bc2ebf12e6dba619
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3
Akademický článek
Antiproliferative activity, cell-cycle arrest, apoptotic induction and LC-HRMS/MS analyses of extracts from two Linum species
Autor: Ryma Mouna, Alexis Broisat, Abdalwahab Ahmed, Marlène Debiossat, Ahcène Boumendjel, Catherine Ghezzi, Zahia Kabouche
Publikováno v: Pharmaceutical Biology, Vol 60, Iss 1, Pp 1491-1501 (2022)
Context Linum is the largest genus of the Linaceae family; the species of this genus are known to have anticancer activity.Objective In this study, ethyl acetate extracts of L. numidicum Murb. (EAELN) and L. trigynum L. (EAELT) were examined, for the
Externí odkaz: https://doaj.org/article/c341976a2dd44048b04932268813c345
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4
Noninvasive assessment of coronary microvascular dysfunction using SPECT myocardial perfusion imaging and myocardial perfusion entropy quantification in a rodent model of type 2 diabetes
Autor: Julien Leenhardt, Gilles Barone-Rochette, Laurent Riou, Marjorie Canu, Gérald Vanzetto, Marie de Fondaumière, Marlène Debiossat, Adrien Carabelli, Daniel Fagret, Alexis Broisat, Catherine Ghezzi
Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 49:809-820
Coronary microvascular dysfunction (CMVD) plays a major role in the occurrence of cardiovascular events (CVE). We recently suggested the clinical potential of myocardial perfusion entropy (MPE) quantification from SPECT myocardial perfusion images (M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe90c095edcd0d62964edf0872e418da
https://doi.org/10.1007/s00259-021-05511-z
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6
Noninvasive assessment of coronary microvascular dysfunction using SPECT myocardial perfusion imaging and myocardial perfusion entropy quantification in a rodent model of type 2 diabetes
Autor: Adrien, Carabelli, Marjorie, Canu, Marie, de Fondaumière, Marlène, Debiossat, Julien, Leenhardt, Alexis, Broisat, Catherine, Ghezzi, Gérald, Vanzetto, Daniel, Fagret, Gilles, Barone-Rochette, Laurent M, Riou
Publikováno v: European journal of nuclear medicine and molecular imaging. 49(3)
Coronary microvascular dysfunction (CMVD) plays a major role in the occurrence of cardiovascular events (CVE). We recently suggested the clinical potential of myocardial perfusion entropy (MPE) quantification from SPECT myocardial perfusion images (M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::850ad2a8835e43d78c84e83e669c1cf9
https://pubmed.ncbi.nlm.nih.gov/34417856
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7
In Vivo Biodistribution and Efficacy Evaluation of NeoB, A Radiotracer Targeted to GRPR, in Mice Bearing Gastrointestinal Stromal Tumor
Autor: Christopher, Montemagno, Florian, Raes, Mitra, Ahmadi, Sandrine, Bacot, Marlène, Debiossat, Julien, Leenhardt, Jean, Boutonnat, Francesca, Orlandi, Donato, Barbato, Mattia, Tedesco, Catherine, Ghezzi, Pascale, Perret, Alexis, Broisat
Publikováno v: Cancers
Cancers, Vol 13, Iss 1051, p 1051 (2021)
Volume 13
Issue 5
NeoB is a radiotracer targeting the gastrin-releasing peptide receptor (GRPR), a G-protein–coupled receptor expressed in various cancers. The aim of the present study was to evaluate the biodistribution and efficacy of this new therapeutic agent in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::06b90edaf8381b18955f80c13e2d04d6
http://europepmc.org/articles/PMC7958597
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8
In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer
Autor: Christopher, Montemagno, Laurent, Dumas, Pierre, Cavaillès, Mitra, Ahmadi, Sandrine, Bacot, Marlène, Debiossat, Audrey, Soubies, Loic, Djaïleb, Julien, Leenhardt, Nicolas de, Leiris, Maeva, Dufies, Gilles, Pagès, Sophie, Hernot, Nick, Devoogdt, Pascale, Perret, Laurent, Riou, Daniel, Fagret, Catherine, Ghezzi, Alexis, Broisat
Publikováno v: Cancers, Vol 11, Iss 7, p 1039 (2019)
Cancers
Cancers, MDPI, 2019, 11 (7), pp.1039. ⟨10.3390/cancers11071039⟩
Cancers, 2019, 11 (7), pp.1039. ⟨10.3390/cancers11071039⟩
Recent progress in breast cancer research has led to the identification of Vascular Cell Adhesion Molecule-1 (VCAM-1) as a key actor of metastatic colonization. VCAM-1 promotes lung-metastases and is associated with clinical early recurrence and poor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0d42587035c5ec4d7007bdd94503c581
https://www.mdpi.com/2072-6694/11/7/1039
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9
Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer
Autor: Brigitte Kerfelec, Mitra Ahmadi, Audrey Soubies, Marlène Debiossat, Daniel Fagret, Pascale Perret, Daniel Baty, Alexis Broisat, Catherine Ghezzi, Christopher Montemagno, Sandrine Bacot, Laurent Riou
Publikováno v: Journal of Nuclear Medicine
Journal of Nuclear Medicine, Society of Nuclear Medicine, 2018, 59 (7), pp.1056-1062. ⟨10.2967/jnumed.117.203489⟩
Journal of Nuclear Medicine, 2018, 59 (7), pp.1056-1062. ⟨10.2967/jnumed.117.203489⟩
International audience; Mesothelin is a cell-surface glycoprotein restricted to mesothelial cells overexpressed in several types of cancer, including triple-negative breast cancer not responding to trastuzumab or hormone-based therapies. Mesothelin-t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccb17f7c3eacbbdc98e4adb62d2397c
https://hal.archives-ouvertes.fr/hal-02115385
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10
Biodistribution and preliminary toxicity studies of nanoparticles made of Biotransesterified β–cyclodextrins and PEGylated phospholipids
Autor: Annabelle Gèze, Christine Lancelon-Pin, V. Blanc-Marquis, Laurent Riou, A. Gentil Dit Maurin, Jean-Luc Putaux, Pascale Perret, Audrey Soubies, Luc Choisnard, Catherine Ghezzi, Denis Wouessidjewe, Marlène Debiossat, Sandrine Bacot, J. Boutonnat
Publikováno v: Materials Science and Engineering: C
Materials Science and Engineering: C, Elsevier, 2018, 85, pp.7-17. ⟨10.1016/j.msec.2017.12.017⟩
Materials Science and Engineering: C, 2018, 85, pp.7-17. ⟨10.1016/j.msec.2017.12.017⟩
Background The modification of β-cyclodextrins (βCDs) by grafting alkyl chains on the primary and/or secondary face yields derivatives (βCD-C10) able to self-organize under nanoprecipitating conditions into nanoparticles (βCD-C10-NP) potentially
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60dad2c7af35b0083d869384d199faad
https://hal.archives-ouvertes.fr/hal-02106169
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