Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Markus Weishaupt"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 97-105 (2013)
Automated oligosaccharide assembly requires suitable linkers to connect the first monosaccharide to a solid support. A new hydrogenolysis-labile linker that is stable under both acidic and basic conditions was designed, synthesized and coupled to dif
Externí odkaz:
https://doaj.org/article/b0456ee9449b4191888481c2ed9bfaa3
Autor:
Theodoros Karagiannis, Mathäus Niemietz, Carlo Unverzagt, Mónica Martínez-Orts, Marie Lott, Nahid Razi, James C. Paulson, Dimitri Ott, Steffen Eller, Ángeles Canales, Markus Weishaupt, Michael Weiss
Publikováno v:
Chembiochem
In human serum immunoglobulin G (IgG), a rare modification of biantennary complex N‐glycans lead to a β1,4‐galactosylated bisecting GlcNAc branch. We found that the bisecting GlcNAc on a biantennary core‐fucosylated N‐glycan was enzymaticall
Autor:
Cathrin Wirkner, Janika Walcher, Matthias Pischl, Joanna Hoffman, Dimitri Ott, Manuel Mönnich, Markus Weishaupt, Theodoros Karagiannis, Carlo Unverzagt, Rachel G. Lichtenstein, Lukas Perkams, Mathäus Niemietz, Lukas Berger, Thomas Luber, Steffen Eller
Publikováno v:
Angewandte Chemie. 128:10643-10648
Die Gegenwart von N-Glycanen mit einer bisecting GlcNAc-Modifikation auf Glycoproteinen hat viele Auswirkungen in der Entwicklungs- und Immunbiologie. Allerdings ist es schwierig diese N-Glycane aus der Natur oder durch Synthese zu erhalten. Fur bise
Autor:
Dimitri Ott, Manuel Mönnich, Joanna Hoffman, Matthias Pischl, Markus Weishaupt, Lukas Berger, Theodoros Karagiannis, Mathäus Niemietz, Janika Walcher, Carlo Unverzagt, Lukas Perkams, Thomas Luber, Steffen Eller
Publikováno v:
Angewandte Chemie (International ed. in English). 57(44)
The occurrence of α1,6-linked core fucose on the N-glycans of mammalian glycoproteins is involved in tumor progression and reduces the bioactivity of antibodies in antibody-dependent cell-mediated cytotoxicity (ADCC). Since core-fucosylated N-glycan
Autor:
Roman Akasov, Anna Pokhvoshcheva, Marina Dorosh, Maria Leko, Markus Weishaupt, Elena Markvicheva, Sergey V. Burov, Thomas Bruckdorfer
Publikováno v:
Proceedings of the 35th European Peptide Symposium.
Autor:
Markus Weishaupt
Das Buch enthüllt: Es gibt eine geheime DNA, die allen erfolgreichen Familienunternehmen gemein ist. Genau zehn Eigenschaften unterscheiden die herausragenden Familienunternehmen von den soliden, die besten von den guten. Markus Weishaupt, Experte f
Autor:
Markus Weishaupt, Manuel Mönnich, Joanna Hoffman, Janika Walcher, Lukas Perkams, Thomas Luber, Matthias Pischl, Dimitri Ott, Carlo Unverzagt, Lukas Berger, Theodoros Karagiannis, Mathäus Niemietz, Cathrin Wirkner, Steffen Eller, Rachel G. Lichtenstein
Publikováno v:
Angewandte Chemie (International ed. in English). 55(35)
The occurrence of N-glycans with a bisecting GlcNAc modification on glycoproteins has many implications in developmental and immune biology. However, these particular N-glycans are difficult to obtain either from nature or through synthesis. We have
Publikováno v:
ChemInform. 42
Publikováno v:
ChemInform. 42
Publikováno v:
Methods in enzymology. 478
Oligosaccharides are involved in many fundamental biological processes. However, relatively little is known about the precise molecular mechanism of action of these macromolecules, because the complexity of these structures impeded their synthesis by