Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Markus Weihrauch"'
Autor:
Gerhard Lehnert, Christian Wittekind, Anett Markwarth, Andrea Tannapfel, Renate Wrbitzky, Markus Weihrauch
Publikováno v:
Human Pathology. 33:884-892
The INK4a-ARF locus, located on chromosome 9p21, encodes 2 cell cycle-regulatory proteins, p16 INKa and p14 ARF , acting through the Rb-CDK4 and p53 pathways. This study was done to investigate the contribution of the INK4a-ARF locus in tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc754a80433b8e529066bf9ef9bac04
https://doi.org/10.1053/hupa.2002.126880
https://doi.org/10.1053/hupa.2002.126880
Autor:
Andrea Tannapfel, Bernd Koch, Gerhard Lehnert, Renate Wrbitzky, Markus Weihrauch, Christian Wittekind, Michael Bader
Publikováno v:
Environmental and Molecular Mutagenesis. 40:36-40
Vinyl chloride (VC) is a potent liver carcinogen that induces angiosarcomas in humans and animals. Recent evidence shows that liver tumors from patients with VC exposure may have a specific K-ras mutation pattern. This study was performed to determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3699d9015c7f2d359079cb540194b417
https://doi.org/10.1002/em.10084
https://doi.org/10.1002/em.10084
Autor:
Gerhard Lehnert, Andrea Tannapfel, Markus Weihrauch, Markus Benicke, Renate Wrbitzky, Ch. Wittekind
Publikováno v:
British Journal of Cancer
Vinyl chloride (VC) is a know animal and human carcinogen associated with liver angiosarcomas (LAS) and hepatocellular carcinomas (HCC). In VC-associated LAS mutations of the K- ras -2 gene have been reported; however, no data about the prevalence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb9cc49d1b199f16670371c15fdc94a
https://doi.org/10.1054/bjoc.2000.1675
https://doi.org/10.1054/bjoc.2000.1675
Autor:
Christian Wittekind, Gerhard Lehnert, Markus Weihrauch, Andrea Tannapfel, Ferdinand Köckerling
Publikováno v:
Cancer. 88:1030-1036
BACKGROUND Vinyl chloride (VC) is a known animal and human carcinogen that is associated with liver angiosarcoma and most likely also with hepatocellular carcinoma (HCC) in humans. METHODS The authors examined the presence of p53 gene mutations in 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::232fbafd7a616785bbb9c513e9c2c410
https://doi.org/10.1002/(sici)1097-0142(20000301)88:5<1030::aid-cncr12>3.0.co
https://doi.org/10.1002/(sici)1097-0142(20000301)88:5<1030::aid-cncr12>3.0.co
Publikováno v:
Medizinische Klinik. 95:545-547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ecd0749353228941265503cd12b406c
https://doi.org/10.1007/pl00002060
https://doi.org/10.1007/pl00002060
Autor:
Christian Wittekind, Andrea Tannapfel, Dirk Uhlmann, Johann Hauss, Markus Weihrauch, Markus Benicke, Renate Wrbitzky
Publikováno v:
Journal of hepatology. 35(1)
Background/Aims : Alterations in the p16 (CDKN2/MTS-1/INK4A) gene have been implicated in the tumorigenesis of different human cancers. Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35da4cde6c190db8fa0d58dbd973d50f
https://pubmed.ncbi.nlm.nih.gov/11495043
https://pubmed.ncbi.nlm.nih.gov/11495043