Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Markus Sprenger-Haussels"'
Autor:
Haiyan E. Liu, Meghah Vuppalapaty, Christian R. Hoerner, Colin P. Bergstrom, Michael Chiu, Clementine Lemaire, James Che, Amanpreet Kaur, Adam Dimmick, Sean Liu, Thomas J. Metzner, Menna Araya, Steve Crouse, Markus Sprenger-Haussels, Martin Schlumpberger, John T. Leppert, Siegfried Hauch, Elodie Sollier, Alice C. Fan
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Therapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor inhibitors (ARIs) and prostate-specific membrane antigen (PSMA). Having the ability to detec
Externí odkaz:
https://doaj.org/article/f147876cb7db462d84fa5bc412a8c4d4
Autor:
Corinna Keup, Vinay Suryaprakash, Siegfried Hauch, Markus Storbeck, Peter Hahn, Markus Sprenger-Haussels, Hans-Christian Kolberg, Mitra Tewes, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-14 (2021)
Abstract Background Single liquid biopsy analytes (LBAs) have been utilized for therapy selection in metastatic breast cancer (MBC). We performed integrative statistical analyses to examine the clinical relevance of using multiple LBAs: matched circu
Externí odkaz:
https://doaj.org/article/39103299acfb493b841699ff8cdd9777
Autor:
Svenja Schneegans, Lelia Lück, Katharina Besler, Leonie Bluhm, Julia‐Christina Stadler, Janina Staub, Rüdiger Greinert, Beate Volkmer, Mikael Kubista, Christoffer Gebhardt, Alexander Sartori, Darryl Irwin, Elina Serkkola, Taija afHällström, Evi Lianidou, Markus Sprenger‐Haussels, Melanie Hussong, Peter Mohr, Stefan W. Schneider, Jonathan Shaffer, Klaus Pantel, Harriet Wikman
Publikováno v:
Molecular Oncology, Vol 14, Iss 5, Pp 1001-1015 (2020)
The combination of liquid biomarkers from a single blood tube can provide more comprehensive information on tumor development and progression in cancer patients compared to single analysis. Here, we evaluated whether a combined analysis of circulatin
Externí odkaz:
https://doaj.org/article/9e3df0b98bd64b93a6f200e8ad0438b0
Autor:
Sabrina Weber, Benjamin Spiegl, Samantha O. Perakis, Christine M. Ulz, Peter M. Abuja, Karl Kashofer, Paul van der Leest, Maria Aguirre Azpurua, Menno Tamminga, Dan Brudzewsky, Dominic G. Rothwell, Sumitra Mohan, Alexander Sartori, Rita Lampignano, Yves Konigshofer, Markus Sprenger-Haussels, Harriet Wikman, Inger R. Bergheim, Vera Kloten, Ed Schuuring, Michael R. Speicher, Ellen Heitzer
Publikováno v:
Cancers, Vol 12, Iss 6, p 1588 (2020)
Molecular profiling from liquid biopsy, in particular cell-free DNA (cfDNA), represents an attractive alternative to tissue biopsies for the detection of actionable targets and tumor monitoring. In addition to PCR-based assays, Next Generation Sequen
Externí odkaz:
https://doaj.org/article/d555baa4a3cb4f3daecabe7688c926e6
Autor:
Anna Babayan, Martin H. D. Neumann, Andrei Herdean, Jonathan M. Shaffer, Melanie Janning, Franca Kobus, Sonja Loges, Francesca Di Pasquale, Mikael Kubista, Martin Schlumpberger, Rita Lampignano, Thomas Krahn, Thomas Schlange, Markus Sprenger-Haussels, Klaus Pantel, Vera Kloten
Publikováno v:
Cancers, Vol 12, Iss 5, p 1166 (2020)
Background: Among emerging circulating biomarkers, miRNA has the potential to detect lung cancer and follow the course of the disease. However, miRNA analysis deserves further standardization before implementation into clinical trials or practice. He
Externí odkaz:
https://doaj.org/article/662b8b3c0e1a4663b2e4736846ea4a55
Autor:
Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Publikováno v:
Cancers, Vol 12, Iss 5, p 1084 (2020)
Cell-free DNA (cfDNA) and circulating tumor cells (CTCs) exhibit great potential for therapy management in oncology. We aimed to establish a multimodal liquid biopsy strategy that is usable with minimized blood volume to deconvolute the genomic compl
Externí odkaz:
https://doaj.org/article/b03e756272ab430795a7d58398e5431b
Autor:
Corinna Keup, Markus Storbeck, Siegfried Hauch, Peter Hahn, Markus Sprenger-Haussels, Mitra Tewes, Pawel Mach, Oliver Hoffmann, Rainer Kimmig, Sabine Kasimir-Bauer
Publikováno v:
Cancers, Vol 11, Iss 2, p 238 (2019)
Liquid biopsy analytes such as cell-free DNA (cfDNA) and circulating tumor cells (CTCs) exhibit great potential for personalized treatment. Since cfDNA and CTCs are considered to give additive information and blood specimens are limited, isolation of
Externí odkaz:
https://doaj.org/article/2b0c5b47ece544c890458b01c53051e2
Autor:
Daniel Enderle, Alexandra Spiel, Christine M Coticchia, Emily Berghoff, Romy Mueller, Martin Schlumpberger, Markus Sprenger-Haussels, Jonathan M Shaffer, Eric Lader, Johan Skog, Mikkel Noerholm
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136133 (2015)
Exosomes and other extracellular vesicles (commonly referred to as EVs) have generated a lot of attention for their potential applications in both diagnostics and therapeutics. The contents of these vesicles are the subject of intense research, and t
Externí odkaz:
https://doaj.org/article/78020a5e270e4250875a5b7f12d4e796
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7207 (2009)
BACKGROUND: Duplex real-time PCR assays have been widely used to determine amounts and concentrations of free circulating DNA in human blood plasma samples. Circulatory plasma DNA is highly fragmented and hence a PCR-based determination of DNA concen
Externí odkaz:
https://doaj.org/article/4e48932281f94209b91557bbc7d8959b
Autor:
Corinna Keup, Rainer Kimmig, Peter Hahn, Markus Sprenger-Haussels, Oliver Hoffmann, Siegfried Hauch, Markus Storbeck, Sabine Kasimir-Bauer
Publikováno v:
Cancer Research. 81:PS2-24
Background: Extensive knowledge about the molecular complexity could benefit therapy management in metastatic breast cancer (MBC). Consequently, we isolated and analyzed mRNA from circulating tumor cells (CTCs), mRNA from extracellular vesicles (EVs)