Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Markus Siegert"'
Publikováno v:
Analytical and Bioanalytical Chemistry
Sulfur mustard (SM) is a banned chemical warfare agent recently used in the Syrian Arab Republic conflict causing erythema and blisters characterized by complicated and delayed wound healing. For medical and legal reasons, the proof of exposure to SM
Autor:
Thomas Gudermann, Markus Siegert, Christian D. Taeger, Alexander Dietrich, Harald John, Julia Herbert, Horst Thiermann, Dirk Steinritz, Harald Mückter, Robin Lüling
Publikováno v:
Archives of Toxicology
Sulfur mustard (SM) is a chemical warfare agent which use is banned under international law and that has been used recently in Northern Iraq and Syria by the so-called Islamic State. SM induces the alkylation of endogenous proteins like albumin and h
Autor:
Alexander Dietrich, Harald John, Dirk Steinritz, Wolfgang Schmeißer, Horst Thiermann, Harald Mückter, Robin Lüling, Thomas Gudermann, Markus Siegert
Publikováno v:
Drug Testing and Analysis. 13:268-282
Sulfur mustard (SM) is a toxic chemical warfare agent deployed in several conflicts within the last 100 years and still represents a threat in terroristic attacks and warfare. SM research focuses on understanding the pathophysiology of SM and identif
Autor:
T. Kranawetvogl, Markus Siegert, Timo Wille, J. Langgartner, C. Mögele-Schmid, Harald John, N. Amend, Horst Thiermann, C. Pflügler, Franz Worek, Marianne Koller
Publikováno v:
Archives of Toxicology
Suicidal ingestion of organophosphorus (OP) or carbamate (CM) compounds challenges health care systems worldwide, particularly in Southeast Asia. The diagnosis and treatment of OP or CM poisoning is traditionally based on the clinical appearance of t
Publikováno v:
Archives of toxicology. 96(8)
In the recent past, the blister agent sulfur mustard (SM) deployed by the terroristic group Islamic State has caused a huge number of civilian and military casualties in armed conflicts in the Middle East. The vaporized or aerolized agent might be in
Publikováno v:
Analytical chemistry. 94(4)
Organophosphorus (OP) nerve agents were used for chemical warfare, assassination, and attempted murder of individuals. Therefore, forensic methods are required to identify known and unknown incorporated OP poisons. Serum is tested for the presence of
Autor:
Harald Mückter, Robin Lüling, Markus Siegert, Harald John, Horst Thiermann, Tanja Popp, Peter Reinemer, Dirk Steinritz, Thomas Gudermann
Publikováno v:
Archives of Toxicology
Creatine kinase (CK) catalyzes the formation of phosphocreatine from adenosine triphosphate (ATP) and creatine. The highly reactive free cysteine residue in the active site of the enzyme (Cys283) is considered essential for the enzymatic activity. In
Autor:
Harald John, Kai Kehe, Dirk Steinritz, Horst Thiermann, Markus Siegert, Simone Rothmiller, Thomas Gudermann, Andreas Kranawetvogl, Simon Lang, Annette M. Schmidt, Tanja Popp
Publikováno v:
Toxicology Letters. 314:172-180
Vesicants cause a multitude of cutaneous reactions like erythema, blisters and ulcerations. After exposure to sulfur mustard (SM) and related compounds, patients present dermal symptoms typically known for chemicals categorized as skin sensitizer (e.
Publikováno v:
Archives of Toxicology. 93:1881-1891
We present the forensic analyses of plasma samples of human victims exposed to sulfur mustard (SM) in a crisis region in the Middle East in 2015. A few hours after exposure, poisoned persons showed typical signs and symptoms of percutaneous SM exposu
Autor:
Markus Siegert, Hans G. Börner, Andreas Kranawetvogl, Harald John, Horst Thiermann, Felix Gandor
Publikováno v:
Drug Testing and Analysis. 11:659-668
Exposure to the vesicant sulfur mustard (SM) may lead to erythema and blistering. Toxicity of SM is hypothesized due to the alkylation of DNA bases and nucleophilic amino acid side chains in proteins (adducts) by forming the hydroxyethylthioethyl (HE