Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Markus Rehberg"'
Autor:
Nathalie Paul, Venetia Karamitsou, Clemens Giegerich, Afshin Sadeghi, Moritz Lücke, Britta Wagenhuber, Alexander Kister, Markus Rehberg
Publikováno v:
Frontiers in Systems Biology, Vol 4 (2024)
In the context of in silico clinical trials, mechanistic computer models for pathophysiology and pharmacology (here Quantitative Systems Pharmacology models, QSP) can greatly support the decision making for drug candidates and elucidate the (potentia
Externí odkaz:
https://doaj.org/article/60fdcd65671c491d81e430f1da7b0bf0
Publikováno v:
Advanced Science, Vol 11, Iss 14, Pp n/a-n/a (2024)
Abstract Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or solid tumors has entered the era of precision medicine that requires systematic knowledge of nano‐biological interactions from multidisciplinary
Externí odkaz:
https://doaj.org/article/9c1965f778b74138a6f8cca995b8bb7f
Autor:
Jeffrey R. Curtis, Huifeng Yun, Lang Chen, Stephanie S. Ford, Hubert van Hoogstraten, Stefano Fiore, Kerri Ford, Amy Praestgaard, Markus Rehberg, Ernest Choy
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 4, Pp 1055-1072 (2023)
Abstract Introduction Clinical trial findings may not be generalizable to routine practice. This study evaluated sarilumab effectiveness in patients with rheumatoid arthritis (RA) and tested the real-world applicability of a response prediction rule,
Externí odkaz:
https://doaj.org/article/80bfab0a874e486da7941d72c601d787
Autor:
Jeffrey R. Curtis, Huifeng Yun, Lang Chen, Stephanie S. Ford, Hubert van Hoogstraten, Stefano Fiore, Kerri Ford, Amy Praestgaard, Markus Rehberg, Ernest Choy
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 1, Pp 217-217 (2023)
Externí odkaz:
https://doaj.org/article/05ceb80625a94892a3e20045335a876e
Autor:
Gizem Günes Günsel, Thomas M. Conlon, Aicha Jeridi, Rinho Kim, Zeynep Ertüz, Niklas J. Lang, Meshal Ansari, Mariia Novikova, Dongsheng Jiang, Maximilian Strunz, Mariia Gaianova, Christine Hollauer, Christina Gabriel, Ilias Angelidis, Sebastian Doll, Jeanine C. Pestoni, Stephanie L. Edelmann, Marlene Sophia Kohlhepp, Adrien Guillot, Kevin Bassler, Hannelore P. Van Eeckhoutte, Özgecan Kayalar, Nur Konyalilar, Tamara Kanashova, Sophie Rodius, Carolina Ballester-López, Carlos M. Genes Robles, Natalia Smirnova, Markus Rehberg, Charu Agarwal, Ioanna Krikki, Benoit Piavaux, Stijn E. Verleden, Bart Vanaudenaerde, Melanie Königshoff, Gunnar Dittmar, Ken R. Bracke, Joachim L. Schultze, Henrik Watz, Oliver Eickelberg, Tobias Stoeger, Gerald Burgstaller, Frank Tacke, Vigo Heissmeyer, Yuval Rinkevich, Hasan Bayram, Herbert B. Schiller, Marcus Conrad, Robert Schneider, Ali Önder Yildirim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Chronic obstructive pulmonary disease is a progressive and incurable chronic condition that involves accumulation of inflammatory macrophages in the lung tissue. Authors here show in mouse models of lung disease that PRMT7, a protein arginine methylt
Externí odkaz:
https://doaj.org/article/a84378847bdf46488a490ed2e06676b9
Autor:
Alexander Vugler, James O’Connell, Mai Anh Nguyen, Dietmar Weitz, Thomas Leeuw, Elizabeth Hickford, Alexander Verbitsky, Xiaoyou Ying, Markus Rehberg, Bruce Carrington, Mark Merriman, Andrew Moss, Jean-Marie Nicholas, Phil Stanley, Sara Wright, Tim Bourne, Yann Foricher, Daniel Brookings, Helen Horsley, Matthias Herrmann, Srinivas Rao, Markus Kohlmann, Peter Florian
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tumor necrosis factor (TNF) is a pleiotropic cytokine belonging to a family of trimeric proteins with both proinflammatory and immunoregulatory functions. TNF is a key mediator in autoimmune diseases and during the last couple of decades several biol
Externí odkaz:
https://doaj.org/article/1ee03f08f53b498dba01c240aad2ca37
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Quantum dots (QDs), are one kind of nanoscale semiconductor crystals with specific electronic and optical properties, offering near-infrared mission and chemically active surfaces. Increasing interest for QDs exists in developing theranostics platfor
Externí odkaz:
https://doaj.org/article/2cf0101ea2ed44fcb782c9daf996aca2
Autor:
Ali Doryab, Mehmet Berat Taskin, Philipp Stahlhut, Andreas Schröppel, Sezer Orak, Carola Voss, Arti Ahluwalia, Markus Rehberg, Anne Hilgendorff, Tobias Stöger, Jürgen Groll, Otmar Schmid
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Evolution has endowed the lung with exceptional design providing a large surface area for gas exchange area (ca. 100 m2) in a relatively small tissue volume (ca. 6 L). This is possible due to a complex tissue architecture that has resulted in one of
Externí odkaz:
https://doaj.org/article/8d7dfc3f549449e7906bde6d1d11ca89
Autor:
Helmut Bischof, Markus Rehberg, Sarah Stryeck, Katharina Artinger, Emrah Eroglu, Markus Waldeck-Weiermair, Benjamin Gottschalk, Rene Rost, Andras T. Deak, Tobias Niedrist, Nemanja Vujic, Hanna Lindermuth, Ruth Prassl, Brigitte Pelzmann, Klaus Groschner, Dagmar Kratky, Kathrin Eller, Alexander R. Rosenkranz, Tobias Madl, Nikolaus Plesnila, Wolfgang F. Graier, Roland Malli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
K+ plays an important role in physiology and disease, but the lack of high specificity K+ sensors limits our understanding of its spatiotemporal dynamics. Here the authors develop genetically-encoded FRET-based probes able to quantify K+ concentratio
Externí odkaz:
https://doaj.org/article/3f0690a062df4c16ae8ab8e09d354078
Autor:
Omary Chillo, Eike Christian Kleinert, Thomas Lautz, Manuel Lasch, Judith-Irina Pagel, Yvonn Heun, Kerstin Troidl, Silvia Fischer, Amelia Caballero-Martinez, Annika Mauer, Angela R.M. Kurz, Gerald Assmann, Markus Rehberg, Sandip M. Kanse, Bernhard Nieswandt, Barbara Walzog, Christoph A. Reichel, Hanna Mannell, Klaus T. Preissner, Elisabeth Deindl
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2197-2207 (2016)
The body has the capacity to compensate for an occluded artery by creating a natural bypass upon increased fluid shear stress. How this mechanical force is translated into collateral artery growth (arteriogenesis) is unresolved. We show that extravas
Externí odkaz:
https://doaj.org/article/29290659cd284108ba015bffadecf23e