Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Markus Pietsch"'
Autor:
Markus Pietsch, Daniel Schurzig, Rolf Salcher, Athanasia Warnecke, Peter Erfurt, Thomas Lenarz, Andrej Kral
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Cochlear variability is of key importance for the clinical use of cochlear implants, the most successful neuroprosthetic device that is surgically placed into the cochlear scala tympani. Despite extensive literature on human cochlear variabi
Externí odkaz:
https://doaj.org/article/3a1eaa3a7f02421d875bb5e75fec1125
Autor:
Carina Lemke, Joscha Christmann, Jiafei Yin, José M. Alonso, Estefanía Serrano, Mourad Chioua, Lhassane Ismaili, María Angeles Martínez-Grau, Christopher D. Beadle, Tatiana Vetman, Florian M. Dato, Ulrike Bartz, Paul W. Elsinghorst, Markus Pietsch, Christa E. Müller, Isabel Iriepa, Timo Wille, José Marco-Contelles, Michael Gütschow
Publikováno v:
ACS Omega, Vol 4, Iss 26, Pp 22161-22168 (2019)
Externí odkaz:
https://doaj.org/article/266dc0bdc6b74364bac17b0fdeeb44a1
Publikováno v:
Therapeutic Advances in Urology, Vol 9 (2017)
Background: The objective of this study was to examine the inhibitory potential of darifenacin, fesoterodine, oxybutynin, propiverine, solifenacin, tolterodine and trospium chloride on the seven major human cytochrome P450 enzymes (CYP) by using a st
Externí odkaz:
https://doaj.org/article/5658ef3a4bd04b7bad7cb9d310b2cb6d
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 803-811 (2005)
The modification of lipoproteins by lipolytic enzymes such as cholesterol esterase (CEase) is assumed to play an important role in the pathogenesis of atherosclerosis. However, details of the activation and inhibition of CEase are still unknown. In t
Externí odkaz:
https://doaj.org/article/ab9dbcd8423b4e34b95be944f00758b0
Autor:
Feodor Braun, Marcel Jaschinski, Philipp Täger, Verena Marmann, Melanie von Brandenstein, Barbara Köditz, Thomas Fischer, Sergio Muñoz-Vázquez, Beate Zimmermanns, Markus Dietlein, Ferdinand Sudbrock, Phillip Krapf, Dietmar Fischer, Axel Heidenreich, Alexander Drzezga, Stefan Kirsch, Markus Pietsch, Klaus Schomäcker
Publikováno v:
Organic & Biomolecular Chemistry. 21:3090-3095
We identified a new estrogen receptor (ER)-targeting ligand with picomolar affinity serving as vehicle for radioiodines. This ligand is a potential radiotheranostics for ER+ male tumours.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::957acc27002d76b7e4e34052ef9ef928
https://doi.org/10.1039/d3ob00114h
https://doi.org/10.1039/d3ob00114h
Autor:
Anna Pepanian, Paul Sommerfeld, Renata Kasprzyk, Toni Kühl, F. Ayberk Binbay, Christoph Hauser, Reik Löser, Robert Wodtke, Marcelina Bednarczyk, Mikolaj Chrominski, Joanna Kowalska, Jacek Jemielity, Diana Imhof, Markus Pietsch
Publikováno v:
Analytical Chemistry. 94:14410-14418
Gα proteins as part of heterotrimeric G proteins are molecular switches essential for G protein-coupled receptor- mediated intracellular signaling. The role of the Gα subunits has been examined for decades with various guanine nucleotides to elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb67b2961476a99199d02aaeb94f41a
https://doi.org/10.1021/acs.analchem.2c03176
https://doi.org/10.1021/acs.analchem.2c03176
Autor:
David Bauer, Robert Wodtke, Markus Laube, Klaus Kopka, Sandra Hauser, Rebecca Rothe, Markus Pietsch, Reik Löser, Jens Pietzsch, Christin Neuber, Johanna Wodtke
Publikováno v:
Journal of Medicinal Chemistry. 64:3462-3478
The transamidase activity of transglutaminase 2 (TGase 2) is considered to be important for several pathophysiological processes including fibrotic and neoplastic tissue growth, whereas in healthy ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60580be33c86c22b3454cefda7d48c1c
https://doi.org/10.1021/acs.jmedchem.1c00096
https://doi.org/10.1021/acs.jmedchem.1c00096
Autor:
Sandra Hauser, Paul Sommerfeld, Johanna Wodtke, Christoph Hauser, Paul Schlitterlau, Jens Pietzsch, Reik Löser, Markus Pietsch, Robert Wodtke
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 9; Pages: 4475
International Journal of Molecular Sciences 23(2022)9, 4475
International Journal of Molecular Sciences 23(2022)9, 4475
Transglutaminase 2 (TGase 2) is a multifunctional protein which is involved in various physiological and pathophysiological processes. The latter also include its participation in the development and progression of malignant neoplasms, which are ofte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2f1cdffd92c621f71c04082a2214c1
Autor:
Michaela Steinkrüger, Sebastian Roman Borgert, Miriam Lauwers, Deeba Ensan, Bernhard Wünsch, Constantin G. Daniliuc, Markus Pietsch, Christian Nienberg, Joachim Jose, Lukas Kröger
Publikováno v:
Chemmedchem
The serine/threonine kinase CK2 modulates the activity of more than 300 proteins and thus plays a crucial role in various physiological and pathophysiological processes including neurodegenerative disorders of the central nervous system and cancer. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990851fa8a3d099bedec779c0c76d75d
http://europepmc.org/articles/PMC7418559
http://europepmc.org/articles/PMC7418559
Autor:
Galyna Pryymachuk, Ehab El-Awaad, Nadin Piekarek, Uta Drebber, Alexandra C. Maul, Juergen Hescheler, Andreas Wodarz, Gabriele Pfitzer, Wolfram F. Neiss, Markus Pietsch, Mechthild M. Schroeter
Publikováno v:
Histochemistry and Cell Biology.
Animal models and clinical studies suggest an influence of angiotensin II (AngII) on the pathogenesis of liver diseases via the renin–angiotensin system. AngII application increases portal blood pressure, reduces bile flow, and increases permeabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::644a4bd4628db4b7f5542f3664fd1481
https://doi.org/10.1007/s00418-022-02087-z
https://doi.org/10.1007/s00418-022-02087-z