Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Markus P. Ghadimi"'
Autor:
Dina Lev, Raphael E. Pollock, Alexander J. Lazar, Kristelle Lusby, Aviad Hoffman, Kari J. Brewer, Jeffery Liu, Eric D. Young, Roman Belousov, Keila E. Torres, Gonzalo Lopez, Markus P. Ghadimi
PDF file - 98K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6a5ada972b280eace2657b5b7ab6db
https://doi.org/10.1158/1535-7163.22499494
https://doi.org/10.1158/1535-7163.22499494
Autor:
Dina Lev, Raphael E. Pollock, Alexander J. Lazar, Kristelle Lusby, Aviad Hoffman, Kari J. Brewer, Jeffery Liu, Eric D. Young, Roman Belousov, Keila E. Torres, Gonzalo Lopez, Markus P. Ghadimi
There is a critical need for efficacious therapeutic strategies to improve the outcome of patients afflicted by malignant peripheral nerve sheath tumors (MPNST). Multiple lines of evidence suggest a role for deregulated phosphoinositide 3-kinase (PI3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40cd0814e2d66c1cb31a38a4d5282de9
https://doi.org/10.1158/1535-7163.c.6536167.v1
https://doi.org/10.1158/1535-7163.c.6536167.v1
Autor:
Dina Lev, Alexander J. Lazar, Belinda Hernandez, Jun Liu, Guy Lahat, Suizhau Wang, Roman Belousov, Svetlana Bolshakov, Theresa Nguyen, Juehui Liu, Eric D. Young, Xianbiao Xie, Markus P. Ghadimi, Gonzalo Lopez, Katelynn Bill, Quan-Sheng Zhu, Keila E. Torres
Purpose: MET signaling has been suggested a potential role in malignant peripheral nerve sheath tumors (MPNST). Here, MET function and blockade were preclinically assessed.Experimental Design: Expression levels of MET, its ligand hepatocyte growth fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39688846d1130a730517f411569491d0
https://doi.org/10.1158/1078-0432.c.6518190
https://doi.org/10.1158/1078-0432.c.6518190
Autor:
Dina Lev, Raphael E. Pollock, Alexander J. Lazar, Chad J. Creighton, Elizabeth G. Demicco, Christine Kivlin, Kristelle Lusby, Gonzalo Lopez, Yiqun Zhang, Roman Belousov, Eric D. Young, Markus P. Ghadimi
PDF file - 235K, Survivin knockdown does not impact the expression of other IAP proteins. Fig S2: Survivin KD and YM155 induce apoptosis in MPNST cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f808fa3e4761032e57d29c46d186ae4
https://doi.org/10.1158/1078-0432.22444440.v1
https://doi.org/10.1158/1078-0432.22444440.v1
Autor:
Dina Lev, Raphael E. Pollock, Alexander J. Lazar, Chad J. Creighton, Elizabeth G. Demicco, Christine Kivlin, Kristelle Lusby, Gonzalo Lopez, Yiqun Zhang, Roman Belousov, Eric D. Young, Markus P. Ghadimi
Purpose: To examine the role of survivin as a therapeutic target in preclinical models of human malignant peripheral nerve sheath tumors (MPNST)Experimental Design: Survivin protein expression levels and subcellular localization were examined immunoh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a40ec7fa99ec0b62467e28baae8c0d4
https://doi.org/10.1158/1078-0432.c.6520167.v1
https://doi.org/10.1158/1078-0432.c.6520167.v1
Autor:
Dina Lev, Alexander J. Lazar, Belinda Hernandez, Jun Liu, Guy Lahat, Suizhau Wang, Roman Belousov, Svetlana Bolshakov, Theresa Nguyen, Juehui Liu, Eric D. Young, Xianbiao Xie, Markus P. Ghadimi, Gonzalo Lopez, Katelynn Bill, Quan-Sheng Zhu, Keila E. Torres
Supplementary Methods, Table 1, Figures 1-4 from Activated MET Is a Molecular Prognosticator and Potential Therapeutic Target for Malignant Peripheral Nerve Sheath Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a4119837f9cfda78f6c8b4061bedc3
https://doi.org/10.1158/1078-0432.22440984.v1
https://doi.org/10.1158/1078-0432.22440984.v1
Autor:
Rainer Görges, Christoph Weber, Christian Ritter, C. Isbert, Gabriele Meyer, Ira Gabor, Christoph-Thomas Germer, Thilo Welsch, Karl-Heinz Schultheis, Philipp Heusch, Georg Flügen, Janina Klasen-Sansone, Johannes Boos, Alexander Wierlemann, Luisa Wördehoff, Christoph Schleich, Marco Bueter, Werner Kenn, Joel Aissa, Stephan Zastrow, Lars Schimmöller, Lars Grenacher, Falk Miese, Ulrich Mödder, Andreas Krieg, Daniel Vallböhmer, Matthias Schauer, Günter Fürst, Verena Plodeck, Wolfram T. Knoefel, Simon Veldhoen, Sophia Blum, Christian Buchbender, Burkhard H. A. von Rahden, Christian Jurowich, Andreas Bockisch, Michael Laniado, Michael Quentin, Kerstin Lenski, Frederic Dietzel, Markus P. Ghadimi, Alexander Rehders, Jürgen Weitz, Hanns-Christoph Held, Stefan A. Topp, Stephanie Sauer, Gerald Antoch, Armin Wiegering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16a7374b4644f390f6bffd077663453f
https://doi.org/10.1055/b-004-132229
https://doi.org/10.1055/b-004-132229
Autor:
Peter W.T. Pisters, Raphael E. Pollock, William W. Tseng, Wei Wei, Dina Lev, Neeta Somaiah, Alexander J. Lazar, John E. Madewell, Aviad Hoffman, Markus P. Ghadimi
Publikováno v:
Annals of Surgical Oncology. 21:2136-2143
Well-differentiated (WD)/dedifferentiated (DD) liposarcoma is the most common soft tissue sarcoma of the retroperitoneum. The frequency of distant metastasis is low and the major burden of disease is locoregional. We sought to define the patterns of
Autor:
Wei Lie Wang, Jason L. Hornick, Tingsheng Peng, Davis R. Ingram, Markus P. Ghadimi, Alexander J. Lazar, Chad J. Creighton, Keila E. Torres, Kristelle Lusby, Chiara Colombo, Aviad Hoffman, Elizabeth G. Demicco, Dina Lev, Raphael E. Pollock, Vinod Ravi
Publikováno v:
Cancer. 119:1868-1877
BACKGROUND. Myxoid liposarcoma (MLPS), a disease especially of young adults with potential for local recurrence and metastasis, currently lacks solid prognostic factors and therapeutic targets. The authors of this report evaluated the natural history
Autor:
Alexander J. Lazar, Dina Lev, Elizabeth G. Demicco, Kristelle Lusby, Matthew L. Anderson, Kelly K. Hunt, Chad J. Creighton, Markus P. Ghadimi, Eric D. Young, Kai Lieh Huang, Yiqun Zhang, Roman Belousov, Raphael E. Pollock, Kari J. Brewer Savannah
Publikováno v:
Clinical Cancer Research. 18:4633-4645
Purpose: The significance of mTOR activation in uterine leiomyosarcoma (ULMS) and its potential as a therapeutic target were investigated. Furthermore, given that effective therapies likely require combination mTOR blockade with inhibition of other t