Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Markus Neumeier"'
Autor:
Sabrina Krautbauer, Markus Neumeier, Lisa Rein-Fischboeck, Elisabeth M. Harberl, Herbert Tilg, Kristina Eisinger, Christa Buechler
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 5, Pp 1151-1165 (2019)
Externí odkaz:
https://doaj.org/article/02029f26a55441f397c3d0a484fc8231
Autor:
Josef Wanninger, Gerhard Liebisch, Kristina Eisinger, Markus Neumeier, Charalampos Aslanidis, Lisa Voggenreiter, Rebekka Pohl, Thomas S. Weiss, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Metabolites, Vol 4, Iss 2, Pp 394-407 (2014)
Adiponectin (APN) exerts multiple beneficial effects in obesity and protects from liver injury. Different APN isoforms circulate in serum, and here, the effect of low molecular weight (LMW) and higher molecular weight (HMW) APN on primary human hepat
Externí odkaz:
https://doaj.org/article/6b6f88d9e88a4b8dba9dac021a30af3a
Autor:
Sabrina Krautbauer, Kristina Eisinger, Markus Neumeier, Yvonne Hader, Roland Buettner, Peter M Schmid, Charalampos Aslanidis, Christa Buechler
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86866 (2014)
Excess fat storage in adipocytes is associated with increased generation of reactive oxygen species (ROS) and impaired activity of antioxidant mechanisms. Manganese superoxide dismutase (MnSOD) is a mitochondrial enzyme involved in detoxification of
Externí odkaz:
https://doaj.org/article/50d90dd1229241b2a18d3f616b2ac50e
Autor:
Andrea Kopp, Lisa Rein-Fischboeck, Sandra Schmidhofer, Kristina Eisinger, Rebekka Pohl, Markus Neumeier, Elisabeth M. Haberl, Andreas Schmid, Sabrina Krautbauer, Christa Buechler, Gerhard Liebisch
Publikováno v:
Experimental and Molecular Pathology. 104:212-221
Alpha-syntrophin (SNTA) is a molecular adapter protein which is expressed in adipocytes. Knock-down of SNTA in 3T3-L1 preadipocytes increases cell proliferation, and differentiated adipocytes display small lipid droplets. These effects are both chara
Publikováno v:
Molecular and Cellular Biochemistry. 393:69-76
Adipogenesis is associated with the upregulation of the antioxidative enzyme manganese superoxide dismutase (MnSOD) suggesting a vital function of this enzyme in adipocyte maturation. In the current work, MnSOD was knocked-down with small-interferenc
Autor:
Markus Neumeier, Kristina Eisinger, Charalampos Aslanidis, Ashraf Dada, Gerd Schmitz, Yvonne Hader, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Experimental and Molecular Pathology. 95:325-329
Adipocytes in obesity have inappropriately low cholesterol while adiponectin release is reduced. Cholesterol shortage may contribute to low adiponectin and 3T3-L1 cells treated with lovastatin have diminished adiponectin in cell supernatants. LDL and
Autor:
E. Eggenhofer, Sandra Schmidhofer, Christa Buechler, Yvonne Hader, Markus Neumeier, Marvin E. Adams, Sabrina Krautbauer, Stanley C. Froehner, Wolfgang Mages, Kristina Eisinger
Publikováno v:
Experimental and Molecular Pathology. 95:180-186
Adiponectin receptor 1 (AdipoR1) is one of the two signaling receptors of adiponectin with multiple beneficial effects in metabolic diseases. AdipoR1 C-terminal peptide is concordant with the consensus sequence of class I PSD-95, disc large, ZO-1 (PD
Autor:
Carlos Enrich, Kristina Eisinger, Rebekka Pohl, Lisa Rein-Fischboeck, Thomas Grewal, Carles Rentero, Anna Alvarez-Guaita, Elisabeth M. Haberl, Markus Neumeier, Christa Buechler, Sabrina Krautbauer
Publikováno v:
Molecular and cellular endocrinology. 439
Lipid storage and adipokine secretion are critical features of adipocytes. Annexin A6 (AnxA6) is a lipid-binding protein regulating secretory pathways and its role in adiponectin release was examined. The siRNA-mediated AnxA6 knock-down in 3T3-L1 pre
Autor:
Hilke Brühl, Sabrina Bauer, Andrea Kopp, Christa Buechler, Sabine Abke, Kristina Eisinger, Andreas Schäffler, Markus Neumeier, Roland Walter
Publikováno v:
Cytokine. 56:573-580
The adipokine adiponectin is well known to affect the function of immune cells and upregulation of CCL2 by adiponectin in monocytes/macrophages has already been reported. In the current study the effect of adiponectin on CCL2, -3, -4, and -5 and thei
Autor:
Thomas S. Weiss, Roland Walter, Josef Wanninger, Markus Neumeier, T. Amann, Andreas Schäffler, Kristina Eisinger, Sabrina Bauer, Christa Buechler, Claus Hellerbrand, Jürgen Schölmerich
Publikováno v:
Experimental and Molecular Pathology. 91:740-744
Connective tissue growth factor (CTGF) is induced in liver fibrosis and enhances the activity of transforming growth factor β (TGFβ). Recently we have shown that the hepatoprotective adipokine adiponectin downregulates CTGF in primary human hepatoc