Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Markus N. Kruse"'
1
Chronic Endothelium-Dependent Regulation of Arterial Blood Pressure by Atrial Natriuretic Peptide: Role of Nitric Oxide and Endothelin-1
Autor: Markus-N. Kruse, Karim Sabrane, Alexandra Gazinski, Michaela Kuhn
Publikováno v: Endocrinology. 150:2382-2387
Atrial natriuretic peptide (ANP), via its guanylyl cyclase (GC)-A receptor, plays a key role in the regulation of arterial blood pressure (ABP) and volume. Endothelial-restricted deletion of GC-A in mice [endothelial cell (EC) GC-A knockout (KO)] res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5af9da3aeaa5fa0dcd643ef7851ad0
https://doi.org/10.1210/en.2008-1360
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2
Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors
Autor: Walter Stöcker, Markus-N. Kruse, Daniel Lottaz, Erwin E. Sterchi, Irene Yiallouros, Hans-Willi Krell, Danny Köhler, Christoph R. Becker
Publikováno v: Biochemical Journal. 378:383-389
Meprin is a zinc endopeptidase of the astacin family, which is expressed as a membrane-bound or secreted protein in mammalian epithelial cells, in intestinal leucocytes and in certain cancer cells. There are two types of meprin subunits, alpha and be
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc10928ed65d7d811d545ca0398c312
https://doi.org/10.1042/bj20031163
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3
Hypervolemic hypertension in mice with systemic inactivation of the (floxed) guanylyl cyclase-A gene by ?MHC-Cre-mediated recombination
Autor: Michaela Kuhn, Rita Holtwick, Boris V. Skryabin, Paulus Kirchhof, Alexander Bubikat, Markus N. Kruse, Melanie Voss, Larissa Fabritz, Jörg Stypmann, Ilka Veltrup, Karim Sabrane
Publikováno v: genesis. 39:288-298
To dissect the tissue-specific functions of atrial natriuretic peptide (ANP), we recently introduced loxP sites into the murine gene for its receptor, guanylyl cyclase-A (GC-A), by homologous recombination (tri-lox GC-A). For either smooth-muscle or
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a509f9cec9cf2c3750d8cd3cbacfbea
https://doi.org/10.1002/gene.20056
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4
Activation of Human Meprin-α in a Cell Culture Model of Colorectal Cancer Is Triggered by the Plasminogen-activating System
Autor: Daniel Lottaz, Markus-N. Kruse, Sandra Rösmann, Dagmar Hahn, Erwin E. Sterchi, Walter Stöcker
Publikováno v: Journal of Biological Chemistry. 277:40650-40658
The activation of latent proenzymes is an important mechanism for the regulation of localized proteolytic activity. Human meprin-alpha, an astacin-like zinc metalloprotease expressed in normal colon epithelial cells, is secreted as a zymogen into the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::020482623210dbc9d75146a754a150f1
https://doi.org/10.1074/jbc.m206203200
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5
Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide
Autor: Michaela Kuhn, Markus N. Kruse, Boris V. Skryabin, Danuta Mitko, Bernd Zetsche, Melanie Zwiener, Masashi Yanagisawa, Larissa Fabritz, Karim Sabrane, Hideo A. Baba
Publikováno v: The Journal of clinical investigation. 115(6)
Atrial natriuretic peptide (ANP), via its vasodilating and diuretic effects, has an important physiological role in the maintenance of arterial blood pressure and volume. Its guanylyl cyclase-A (GC-A) receptor is highly expressed in vascular endothel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382885570ed8eb0126d826ec09c90785
https://pubmed.ncbi.nlm.nih.gov/15931381
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8
Differences in the Activation Mechanism between the α and β Subunits of Human Meprin
Autor: Walter Stöcker, Erwin E. Sterchi, Sandra Rösmann, Harris, Markus-N. Kruse, Danny Köhler, Christoph R. Becker, K. A. Slotty
Publikováno v: Biological Chemistry. 384
Meprins are zinc-endopeptidases of the astacin family, which are expressed as membrane-bound or secreted forms in renal and intestinal brush-border membranes of mouse, rat and man. There are two types of meprin subunits, alpha and beta, which form di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e096ff55e87be6ff2f875ebce2de38b2
https://doi.org/10.1515/bc.2003.092
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