Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Markus Muschen"'
Autor:
Adeleh Taghi Khani, Anil Kumar, Ashly Sanchez Ortiz, Kelly C. Radecki, Soraya Aramburo, Sung June Lee, Zunsong Hu, Behzad Damirchi, Mary Y. Lorenson, Xiwei Wu, Zhaohui Gu, William Stohl, Ignacio Sanz, Eric Meffre, Markus Müschen, Stephen J. Forman, Jean L. Koff, Ameae M. Walker, Srividya Swaminathan
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Malignant human B cells express autocrine prolactin (PRL), which has the potential to engage the long isoform and intermediate form of the PRL receptor to promote proliferation and/or survival.
Externí odkaz:
https://doaj.org/article/84ab9aaf43bd41779abbb7561b6c18e0
Autor:
Mingli Li, Lu Yang, Anthony K. N. Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson, Xiaobao Xu, Wen‐Han Chang, Kazuya Miyashita, Priyanka Singh, Leisi Zhang, Maggie Li, Jun Wu, Jinhui Wang, Bryan Chen, Lai N. Chan, Jaewoong Lee, Xu Hannah Zhang, Steven T. Rosen, Markus Müschen, Jun Qi, Jianjun Chen, Kevin Hiom, Alexander J. R. Bishop, Chun‐Wei Chen
Publikováno v:
Advanced Science, Vol 10, Iss 17, Pp n/a-n/a (2023)
Abstract Epigenetic dysregulation is reported in multiple cancers including Ewing sarcoma (EwS). However, the epigenetic networks underlying the maintenance of oncogenic signaling and therapeutic response remain unclear. Using a series of epigenetics
Externí odkaz:
https://doaj.org/article/d8eb48a7527744de8eb5ea7136bf0bee
Autor:
Heather A. Ogana, Samantha Hurwitz, Chih-Lin Hsieh, Huimin Geng, Markus Müschen, Deepa Bhojwani, Mark A. Wolf, James Larocque, Michael R. Lieber, Yong Mi Kim
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
As effective therapies for relapse and refractory B-cell acute lymphoblastic leukemia (B-ALL) remain problematic, novel therapeutic strategies are needed. Artemis is a key endonuclease in V(D)J recombination and nonhomologous end joining (NHEJ) of DN
Externí odkaz:
https://doaj.org/article/16124452d48a4bd1a4732545972846eb
Autor:
Yu-Ting Tan, Lin Ye, Fei Xie, Jiaming Wang, Markus Müschen, Sai-Juan Chen, Yuet Wai Kan, Han Liu
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/ada575e3ae9249feaac4c41cf2911b61
Autor:
Nicholas A Graham, Aspram Minasyan, Anastasia Lomova, Ashley Cass, Nikolas G Balanis, Michael Friedman, Shawna Chan, Sophie Zhao, Adrian Delgado, James Go, Lillie Beck, Christian Hurtz, Carina Ng, Rong Qiao, Johanna ten Hoeve, Nicolaos Palaskas, Hong Wu, Markus Müschen, Asha S Multani, Elisa Port, Steven M Larson, Nikolaus Schultz, Daniel Braas, Heather R Christofk, Ingo K Mellinghoff, Thomas G Graeber
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 2, Pp 1-25 (2017)
Abstract Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but
Externí odkaz:
https://doaj.org/article/ecca9cc2cad345a0a0b562644ca81d88
Autor:
Ilaria Iacobucci, Annalisa Lonetti, Daniela Cilloni, Francesca Messa, Anna Ferrari, Roberta Zuntini, Simona Ferrari, Emanuela Ottaviani, Francesca Arruga, Stefania Paolini, Cristina Papayannidis, Pier Paolo Piccaluga, Simona Soverini, Giuseppe Saglio, Fabrizio Pane, Anna Baruzzi, Marco Vignetti, Giorgio Berton, Antonella Vitale, Sabina Chiaretti, Markus Müschen, Robin Foà, Michele Baccarani, Giovanni Martinelli
Publikováno v:
Haematologica, Vol 93, Iss 12 (2008)
Background Ikaros is the prototypic member of a Kruppel-like zinc finger transcription factor subfamily that is required for normal hematopoietic cell differentiation and proliferation, particularly in the lymphoid lineages. Alternative splicing can
Externí odkaz:
https://doaj.org/article/f2fa2aadfa6a4c8a9c31e7e094d57c09
Autor:
Ruishu Deng, Christian Hurtz, Qingxiao Song, Chanyu Yue, Gang Xiao, Hua Yu, Xiwei Wu, Markus Muschen, Stephen Forman, Paul J. Martin, Defu Zeng
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Chronic graft-versus-host disease (cGVHD) is mediated by specific CD4 and B cells, but the relative contribution of extrafollicular and germinal centre (GC) T-B interaction is unclear. Here the authors show that the extrafollicular expansion of a spe
Externí odkaz:
https://doaj.org/article/4ae9ab1b935340a8a29b9c8d5a7b619c
Autor:
Steven Grant, Markus Muschen, Nikhil Kolluri, Nguyen Nguyen, Nicholas Jordan, Lora Kramer, Elisa Attkisson, Yun Dai, Tri Nguyen
Supplementary Figures S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f79d2aee113b54fa6acf86e3fc6b10
https://doi.org/10.1158/1078-0432.22440843
https://doi.org/10.1158/1078-0432.22440843
Autor:
Steven Grant, Markus Muschen, Nikhil Kolluri, Nguyen Nguyen, Nicholas Jordan, Lora Kramer, Elisa Attkisson, Yun Dai, Tri Nguyen
Purpose: The purpose of this study was to determine whether histone deacetylase (HDAC) inhibitors (HDACI) such as vorinostat or entinostat (SNDX-275) could increase the lethality of the dual Bcr/Abl-Aurora kinase inhibitor KW-2449 in various Bcr/Abl+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388f344a5f4ebea66d8d60af740c2d6c
https://doi.org/10.1158/1078-0432.c.6518106
https://doi.org/10.1158/1078-0432.c.6518106
Autor:
Tamara, Mirzapoiazova, Gang, Xiao, Bolot, Mambetsariev, Mohd W, Nasser, Emily, Miaou, Sharad S, Singhal, Saumya, Srivastava, Isa, Mambetsariev, Michael S, Nelson, Arin, Nam, Amita, Behal, Leonidas, Arvanitis, Pranita, Atri, Markus, Muschen, François L H, Tissot, James, Miser, John S, Kovach, Martin, Sattler, Surinder K, Batra, Prakash, Kulkarni, Ravi, Salgia
Publikováno v:
Mol Cancer Ther
Protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of apoptosis, proliferation, and DNA-damage response, is overexpressed in many cancers, including small cell lung cancer (SCLC). Here we report that LB100, a sma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee468aec5dec422fba227a1f4a0782a5
https://doi.org/10.1158/1535-7163.mct-21-0013
https://doi.org/10.1158/1535-7163.mct-21-0013