Zobrazeno 1 - 10
of 418
pro vyhledávání: '"Markus Mitterhauser"'
Autor:
Eva-Maria Patronas, Theresa Balber, Anne Miller, Barbara Katharina Geist, Antje Michligk, Chrysoula Vraka, Maximilian Krisch, Nataliya Rohr-Udilova, Arvand Haschemi, Helmut Viernstein, Marcus Hacker, Markus Mitterhauser
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108137- (2023)
Summary: Studies indicate that the radiotracer 2-[18F]fluoro-2-deoxy-D-glucose (2-[18F]FDG) can be metabolized beyond 2-[18F]FDG-6-phosphate (2-[18F]FDG-6-P), but its metabolism is incompletely understood. Most importantly, it remains unclear whether
Externí odkaz:
https://doaj.org/article/461eb486543f4f85bb6d597fb882a215
Autor:
Matej Murgaš, Jakob Unterholzner, Peter Stöhrmann, Cécile Philippe, Godber M. Godbersen, Lukas Nics, Murray B. Reed, Chrysoula Vraka, Thomas Vanicek, Wolfgang Wadsak, Georg S. Kranz, Andreas Hahn, Markus Mitterhauser, Marcus Hacker, Siegfried Kasper, Rupert Lanzenberger, Pia Baldinger-Melich
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Theta-burst stimulation (TBS) represents a brain stimulation technique effective for treatment-resistant depression (TRD) as underlined by meta-analyses. While the methodology undergoes constant refinement, bilateral stimulation of the dorso
Externí odkaz:
https://doaj.org/article/74f373a091ef4800ad7ed76e4aac65c9
Autor:
Velina S. Atanasova, Crhistian de Jesus Cardona, Václav Hejret, Andreas Tiefenbacher, Theresia Mair, Loan Tran, Janette Pfneissl, Kristina Draganić, Carina Binder, Julijan Kabiljo, Janik Clement, Katharina Woeran, Barbara Neudert, Sabrina Wohlhaupter, Astrid Haase, Sandra Domazet, Markus Hengstschläger, Markus Mitterhauser, Leonhard Müllauer, Boris Tichý, Michael Bergmann, Gabriele Schweikert, Markus Hartl, Helmut Dolznig, Gerda Egger
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1391-1419 (2023)
Background & Aims: Patient-derived organoid cancer models are generated from epithelial tumor cells and reflect tumor characteristics. However, they lack the complexity of the tumor microenvironment, which is a key driver of tumorigenesis and therapy
Externí odkaz:
https://doaj.org/article/4731d5078fae4db69082355f0d4fbdc9
Autor:
Lucas Rischka, Matej Murgaš, Verena Pichler, Chrysoula Vraka, Ivo Rausch, Dietmar Winkler, Lukas Nics, Sazan Rasul, Leo Robert Silberbauer, Murray Bruce Reed, Godber Mathis Godbersen, Jakob Unterholzner, Patricia Handschuh, Gregor Gryglewski, Thomas Mindt, Markus Mitterhauser, Andreas Hahn, Simon Mensah Ametamey, Wolfgang Wadsak, Rupert Lanzenberger, Marcus Hacker
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Background The NMDA receptor (NMDAR) plays a key role in the central nervous system, e.g., for synaptic transmission. While synaptic NMDARs are thought to have protective characteristics, activation of extrasynaptic NMDARs might trigger exci
Externí odkaz:
https://doaj.org/article/d21c633daec24b5eae645523e1066d2c
Autor:
Nicolai Huebner, Sazan Rasul, Pascal Baltzer, Paola Clauser, Karl Hermann Grubmüller, Markus Mitterhauser, Marcus Hacker, Axel Heidenreich, Pawel Rajwa, Harun Fajkovic, Shahrokh F. Shariat, Bernhard Grubmüller
Publikováno v:
European Urology Open Science, Vol 40, Iss , Pp 117-124 (2022)
Background: Prostate-specific membrane antigen (PSMA) targeted molecular imaging using positron emission tomography (PET) has significantly improved the diagnosis and treatment of prostate cancer (PCA). Objective: To assess the feasibility and compar
Externí odkaz:
https://doaj.org/article/e097a00fc9874abda671694ab6751151
Autor:
Julia Raitanen, Bernadette Barta, Hermann Fuchs, Marcus Hacker, Theresa Balber, Dietmar Georg, Markus Mitterhauser
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17015 (2023)
In vitro therapeutic efficacy studies are commonly conducted in cell monolayers. However, three-dimensional (3D) tumor spheroids are known to better represent in vivo tumors. This study used [177Lu]Lu-PSMA-I&T, an already clinically applied radiophar
Externí odkaz:
https://doaj.org/article/a1af7da461e545eb90298062c69a0134
Quality Assurance Investigations and Impurity Characterization during Upscaling of [177Lu]Lu-PSMAI&T
Autor:
Stefan Schmitl, Julia Raitanen, Stephan Witoszynskyj, Eva-Maria Patronas, Lukas Nics, Marius Ozenil, Victoria Weissenböck, Thomas L. Mindt, Marcus Hacker, Wolfgang Wadsak, Marie R. Brandt, Markus Mitterhauser
Publikováno v:
Molecules, Vol 28, Iss 23, p 7696 (2023)
[177Lu]Lu-PSMAI&T is widely used for the radioligand therapy of metastatic castration-resistant prostate cancer (mCRPC). Since this kind of therapy has gained a large momentum in recent years, an upscaled production process yielding multiple patient
Externí odkaz:
https://doaj.org/article/7b356a1cd6d24ff4a37a2ec6e5556759
Autor:
Barbara Happl, Marie Brandt, Theresa Balber, Katarína Benčurová, Zeynep Talip, Alexander Voegele, Petra Heffeter, Wolfgang Kandioller, Nicholas P. Van der Meulen, Markus Mitterhauser, Marcus Hacker, Bernhard K. Keppler, Thomas L. Mindt
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2626 (2023)
The first-in-class ruthenium-based chemotherapeutic agent BOLD-100 (formerly IT-139, NKP-1339, KP1339) is currently the subject of clinical evaluation for the treatment of gastric, pancreatic, colorectal and bile duct cancer. A radiolabeled version o
Externí odkaz:
https://doaj.org/article/0103cd691d3e43eabe126bd088ed876e
Autor:
Sazan Rasul, Barbara Katharina Geist, Holger Einspieler, Harun Fajkovic, Shahrokh F. Shariat, Stefan Schmitl, Markus Mitterhauser, Rainer Bartosch, Werner Langsteger, Pascal Andreas Thomas Baltzer, Thomas Beyer, Daria Ferrara, Alexander R. Haug, Marcus Hacker, Ivo Rausch
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13677 (2023)
To investigate the use of kinetic parameters derived from direct Patlak reconstructions of [68Ga]Ga-PSMA-11 positron emission tomography/computed tomography (PET/CT) to predict the histological grade of malignancy of the primary tumor of patients wit
Externí odkaz:
https://doaj.org/article/1b46b39c9b44434b9f3fc9eb6b853522
Autor:
Laszlo Papp, Sazan Rasul, Clemens P. Spielvogel, Denis Krajnc, Nina Poetsch, Adelheid Woehrer, Eva-Maria Patronas, Boglarka Ecsedi, Julia Furtner, Markus Mitterhauser, Ivo Rausch, Georg Widhalm, Thomas Beyer, Marcus Hacker, Tatjana Traub-Weidinger
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionAmino-acid positron emission tomography (PET) is a validated metabolic imaging approach for the diagnostic work-up of gliomas. This study aimed to evaluate sex-specific radiomic characteristics of L-[S-methyl-11Cmethionine (MET)-PET image
Externí odkaz:
https://doaj.org/article/e7b98d09cc804db6aebfc134547b8950