Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Markus Meißner"'
Autor:
Philipp Licht, Nazzareno Dominelli, Johannes Kleemann, Stefan Pastore, Elena-Sophia Müller, Maximilian Haist, Kim Sophie Hartmann, Henner Stege, Matthias Bros, Markus Meissner, Stephan Grabbe, Ralf Heermann, Volker Mailänder
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Mycosis fungoides (MF) is the most common entity of Cutaneous T cell lymphomas (CTCL) and is characterized by the presence of clonal malignant T cells in the skin. The role of the skin microbiome for MF development and progression are curren
Externí odkaz:
https://doaj.org/article/ac23a0518b51423d9ef037eec3ac22ce
Autor:
Elias A. T. Koch, Anne Petzold, Edgar Dippel, Michael Erdmann, Anja Gesierich, Ralf Gutzmer, Jessica C. Hassel, Sebastian Haferkamp, Katharina C. Kähler, Nicole Kreuzberg, Ulrike Leiter, Carmen Loquai, Friedegund Meier, Markus Meissner, Peter Mohr, Claudia Pföhler, Farnaz Rahimi, Beatrice Schell, Patrick Terheyden, Kai-Martin Thoms, Selma Ugurel, Jens Ulrich, Jochen Utikal, Michael Weichenthal, Fabian Ziller, Carola Berking, Markus V. Heppt
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionDespite recent advancements in the treatment of metastatic uveal melanoma (UM), the availability of further treatment options remains limited and the prognosis continues to be poor in many cases. In addition to tebentafusp, immune checkpo
Externí odkaz:
https://doaj.org/article/e37aacd9f05d43b681af7a4bbdfeb024
Autor:
Igor Hrgovic, Eva Zöller, Monika Doll, Tsige Hailemariam-Jahn, Thilo Jakob, Roland Kaufmann, Markus Meissner, Johannes Kleemann
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 67-80 (2023)
Tumor-induced lymphangiogenesis is strongly associated with the formation of tumor metastasis. Therefore, the regulation of lymphangiogenesis offers a promising target in cancer therapy. Arsenic trioxide (ATO) is highly effective in the treatment of
Externí odkaz:
https://doaj.org/article/c4fd3bb368434a48bf4d340b790f9caf
Autor:
Christen M. Klinger, Elena Jimenez-Ruiz, Tobias Mourier, Andreas Klingl, Leandro Lemgruber, Arnab Pain, Joel B. Dacks, Markus Meissner
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113740- (2024)
Summary: The organelle paralogy hypothesis (OPH) aims to explain the evolution of non-endosymbiotically derived organelles. It predicts that lineage-specific pathways or organelles should result when identity-encoding membrane-trafficking components
Externí odkaz:
https://doaj.org/article/c4c4ae4ff71f484e941e13d6a4c9df8b
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001937 (2023)
Apicomplexa are obligate intracellular parasites. While most species are restricted to specific hosts and cell types, Toxoplasma gondii can invade every nucleated cell derived from warm-blooded animals. This broad host range suggests that this parasi
Externí odkaz:
https://doaj.org/article/1f0afea7340241a8a4e93fa70cf01ab5
Autor:
Franziska K. Krebs, Emily R. Trzeciak, Sophia Zimmer, Deniz Özistanbullu, Heidrun Mitzel‐Rink, Markus Meissner, Stephan Grabbe, Carmen Loquai, Andrea Tuettenberg
Publikováno v:
Cancer Medicine, Vol 10, Iss 5, Pp 1562-1575 (2021)
Abstract Background Malignant melanoma is an immunogenic skin cancer with an increasing global incidence. Advanced stages of melanoma have poor prognoses. Currently, there are no reliable parameters to predict a patient's response to immune checkpoin
Externí odkaz:
https://doaj.org/article/da7d9a5d630448159fc2737a5b918d40
Autor:
Hans Urban, Eike Steidl, Elke Hattingen, Katharina Filipski, Markus Meissner, Martin Sebastian, Agnes Koch, Adam Strzelczyk, Marie-Thérèse Forster, Peter Baumgarten, Michael W. Ronellenfitsch, Joachim P. Steinbach, Martin Voss
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
BackgroundThe inclusion of immune checkpoint inhibitors (ICIs) in therapeutic algorithms has led to significant survival benefits in patients with various metastatic cancers. Concurrently, an increasing number of neurological immune related adverse e
Externí odkaz:
https://doaj.org/article/978d213715094feda5a7ddfb8f557beb
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT Apicomplexan parasites, such as Toxoplasma gondii and Plasmodium falciparum, are the cause of many important human and animal diseases. While T. gondii tachyzoites replicate through endodyogeny, during which two daughter cells are formed wit
Externí odkaz:
https://doaj.org/article/7b853ce546c24ffd98c13f7fa108dcc8
Autor:
Bastian Schilling, Sascha Tierling, Jörn Walter, Katharina Filipski, Michael Scherer, Kim N. Zeiner, Andreas Bucher, Johannes Kleemann, Philipp Jurmeister, Tabea I. Hartung, Markus Meissner, Karl H. Plate, Tim R. Fenton, Pia S. Zeiner, Patrick N. Harter
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Therapies based on targeting immune checkpoints have revolutionized the treatment of metastatic melanoma in recent years. Still, biomarkers predicting long-term therapy responses are lacking.Methods A novel approach of reference-free decon
Externí odkaz:
https://doaj.org/article/ab979c45047c46cd8cb514714ad3742b
Autor:
Markus V. Heppt, Teresa Amaral, Katharina C. Kähler, Lucie Heinzerling, Jessica C. Hassel, Markus Meissner, Nicole Kreuzberg, Carmen Loquai, Lydia Reinhardt, Jochen Utikal, Evelyn Dabrowski, Anja Gesierich, Claudia Pföhler, Patrick Terheyden, Kai-Martin Thoms, Lisa Zimmer, Thomas K. Eigentler, Michael C. Kirchberger, Henner M. Stege, Friedegund Meier, Max Schlaak, Carola Berking
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Uveal melanoma (UM) is highly refractory to treatment with dismal prognosis in advanced stages. The value of the combined checkpoint blockade with CTLA-4 and PD-1 inhibition in metastatic UM is currently unclear. Methods Patients
Externí odkaz:
https://doaj.org/article/39e18ef3acc940829b41d0958141f699