Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Markus Mandl"'
Autor:
Markus Mandl, Hans P. Viertler, Florian M. Hatzmann, Camille Brucker, Sonja Großmann, Petra Waldegger, Tina Rauchenwald, Monika Mattesich, Marit Zwierzina, Gerhard Pierer, Werner Zwerschke
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 164-174 (2022)
We established a functional adipose organoid model system for human adipose stem/progenitor cells (ASCs) isolated from white adipose tissue (WAT). ASCs were forced to self-aggregate by a hanging-drop technique. Afterwards, spheroids were transferred
Externí odkaz:
https://doaj.org/article/53dd2b959a88406aba5caa1587a647da
Autor:
Florian M Hatzmann, Sonja Großmann, Petra Waldegger, G Jan Wiegers, Markus Mandl, Tina Rauchenwald, Gerhard Pierer, Werner Zwerschke
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 601-615 (2022)
The capacity of adipose stem/progenitor cells (ASCs) to undergo self-renewal and differentiation is crucial for adipose tissue homoeostasis, regeneration and expansion. However, the heterogeneous ASC populations of the adipose lineage constituting ad
Externí odkaz:
https://doaj.org/article/e36cc2792683489cab300b572b2aefb2
Autor:
Markus Mandl, Hans P. Viertler, Maria Zopoglou, Maria C. Mitterberger-Vogt, Juliane Gasser, Florian M. Hatzmann, Tina Rauchenwald, Marit E. Zwierzina, Monika Mattesich, Alexander K. H. Weiss, Lorenza Mottes, Camille Brucker, Petra Waldegger, Gerhard Pierer, Werner Zwerschke
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Misalignment of physiological circadian rhythms promotes obesity which is characterized by white adipose tissue (WAT) expansion. Differentiation of Adipose stem/progenitor cells (ASCs) contributes to WAT increase but the importance of the ce
Externí odkaz:
https://doaj.org/article/66e38723e5c74f4fbeb7f4f6b0631e28
Autor:
Markus Mandl, Heike Ritthammer, Asim Ejaz, Sonja A. Wagner, Florian M. Hatzmann, Saphira Baumgarten, Hans P. Viertler, Marit E. Zwierzina, Monika Mattesich, Valerie Schiller, Tina Rauchenwald, Christian Ploner, Petra Waldegger, Gerhard Pierer, Werner Zwerschke
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 626-635 (2020)
The CRISPR/Cas9 system is a powerful tool to generate a specific loss-of-function phenotype by gene knockout (KO). However, this approach is challenging in primary human cells. In this technical report, we present a reliable protocol to achieve a fun
Externí odkaz:
https://doaj.org/article/ea96581b76fa40a48032f2164c93487a
Autor:
Claudia Krautgasser, Markus Mandl, Florian M. Hatzmann, Petra Waldegger, Monika Mattesich, Werner Zwerschke
Publikováno v:
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-12 (2019)
Abstract Background The proliferation and adipogenic differentiation of adipose stromal cells (ASCs) are complex processes comprising major phenotypical alterations driven by up- and downregulation of hundreds of genes. Quantitative RT-PCR can be emp
Externí odkaz:
https://doaj.org/article/365ef80144134943927a8e8a3948d0ed
Autor:
Markus Mandl, Reinhard Depping
Publikováno v:
Cancer Cell International, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT) participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular oxygen tension. In hypoxia, HIF-1α and ARNT form the tra
Externí odkaz:
https://doaj.org/article/283f7af409754bcdb18f499cf7a27a28
Autor:
Florian M. Hatzmann, Asim Ejaz, G. Jan Wiegers, Markus Mandl, Camille Brucker, Stefan Lechner, Tina Rauchenwald, Marit Zwierzina, Saphira Baumgarten, Sonja Wagner, Monika Mattesich, Petra Waldegger, Gerhard Pierer, Werner Zwerschke
Publikováno v:
Cells, Vol 10, Iss 2, p 214 (2021)
We explore the status of quiescence, stemness and adipogenic differentiation capacity in adipose stem/progenitor cells (ASCs) ex vivo, immediately after isolation from human subcutaneous white adipose tissue, by sorting the stromal vascular fraction
Externí odkaz:
https://doaj.org/article/6c5b49aa2b4c4af498332e175a64e09f
Autor:
Florian M. Hatzmann, Camille Brucker, Hans P. Viertler, Marit Zwierzina, Asim Ejaz, Markus Mandl, Monika Mattesich, Jochen Springer, Gerhard Pierer, Werner Zwerschke, Saphira Baumgarten, Heike Ritthammer, Sonja A. Wagner, Petra Waldegger
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
The role of Ras-Mitogen-activated protein kinase (MAPK) signaling in cellular aging is not precisely understood. Recently, we identified Sprouty1 (SPRY1) as a weight-loss target gene in human adipose stem/progenitor cells (ASCs) and showed that Sprou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd8c586a78feddfe04cb8980c6526bb
http://europepmc.org/articles/PMC7662188
http://europepmc.org/articles/PMC7662188
Autor:
Monika Mattesich, Saphira Baumgarten, Christian Ploner, Hans P. Viertler, Petra Waldegger, Gerhard Pierer, Sonja A. Wagner, Florian M. Hatzmann, Asim Ejaz, Valerie Schiller, Werner Zwerschke, Markus Mandl, Marit Zwierzina, Heike Ritthammer, Tina Rauchenwald
Publikováno v:
Adipocyte, Vol 9, Iss 1, Pp 626-635 (2020)
Adipocyte
article-version (VoR) Version of Record
Adipocyte
article-version (VoR) Version of Record
The CRISPR/Cas9 system is a powerful tool to generate a specific loss-of-function phenotype by gene knockout (KO). However, this approach is challenging in primary human cells. In this technical report, we present a reliable protocol to achieve a fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40565776d53345f283461baa5f9c42ff
https://doi.org/10.1080/21623945.2020.1834230
https://doi.org/10.1080/21623945.2020.1834230
Autor:
Werner Zwerschke, Petra Waldegger, Claudia Krautgasser, Markus Mandl, Monika Mattesich, Florian M. Hatzmann
Publikováno v:
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-12 (2019)
Cellular & Molecular Biology Letters
Cellular & Molecular Biology Letters
Background The proliferation and adipogenic differentiation of adipose stromal cells (ASCs) are complex processes comprising major phenotypical alterations driven by up- and downregulation of hundreds of genes. Quantitative RT-PCR can be employed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1537d3cbbb6072bc4ed3299c249fc3c4
http://link.springer.com/article/10.1186/s11658-019-0140-6
http://link.springer.com/article/10.1186/s11658-019-0140-6