Metabolic energy conservation for fermentative product formation

Autor: Pauline L. Folch, Markus M.M. Bisschops, Ruud A. Weusthuis

Publikováno v: Microbial Biotechnology, Vol 14, Iss 3, Pp 829-858 (2021)

Summary Microbial production of bulk chemicals and biofuels from carbohydrates competes with low‐cost fossil‐based production. To limit production costs, high titres, productivities and especially high yields are required. This necessitates metab

Externí odkaz: https://doaj.org/article/c13667c2a49b46759b72d5fbfb5a2080

Oxygen availability strongly affects chronological lifespan and thermotolerance in batch cultures of Saccharomyces cerevisiae

Autor: Markus M.M. Bisschops, Tim Vos, Rubén Martínez-Moreno, Pilar de la Torre Cortés, Jack T. Pronk, Pascale Daran-Lapujade

Publikováno v: Microbial Cell, Vol 2, Iss 11, Pp 429-444 (2015)

Stationary-phase (SP) batch cultures of Saccharomyces cerevisiae, in which growth has been arrested by carbon-source depletion, are widely applied to study chronological lifespan, quiescence and SP-associated robustness. Based on this type of experim

Externí odkaz: https://doaj.org/article/16f30b037e9a441ea8bea4bda9b7ffff

The Crabtree Effect Shapes the Saccharomyces cerevisiae Lag Phase during the Switch between Different Carbon Sources

Autor: Dries De Maeyer, Brigida Gallone, Jan Michiels, Nuria Barrajón Simancas, Joost van den Brink, Elise van Bael, Tom Wenseleers, Gemma Perez-Samper, Abbas Jariani, Markus M.M. Bisschops, Pascale Daran-Lapujade, Daniel Solis-Escalante, Bram Cerulus, Lieselotte Vermeersch, Kathleen Marchal, Kevin J. Verstrepen

Publikováno v: mBio
mBio, 9(5), e01331-18
MBIO
mBio (online), 9(5)
mBio, Vol 9, Iss 5 (2018)
mBio, Vol 9, Iss 5, p e01331-18 (2018)

The lag phase is arguably one of the prime characteristics of microbial growth. Longer lag phases result in lower competitive fitness in variable environments, and the duration of the lag phase is also important in many industrial processes where lon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29439e55f5977e89ef64a9c57687527b

Extreme calorie restriction in yeast retentostats induces uniform non-quiescent growth arrest

Autor: Pascale Daran-Lapujade, Jack T. Pronk, Anne Doerr, Frank J. Bruggeman, Markus M.M. Bisschops, Peter J.T. Verheijen, Marijke A. H. Luttik

Publikováno v: Biochimica et Biophysica Acta-Molecular Cell Research, 1864(1), 231-242. Elsevier
Bisschops, M M M, Luttik, M A H, Doerr, A, Verheijen, P J T, Bruggeman, F, Pronk, J T & Daran-Lapujade, P 2017, ' Extreme calorie restriction in yeast retentostats induces uniform non-quiescent growth arrest ', Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1864, no. 1, pp. 231-242 . https://doi.org/10.1016/j.bbamcr.2016.11.002

Non-dividing Saccharomyces cerevisiae cultures are highly relevant for fundamental and applied studies. However, cultivation conditions in which non-dividing cells retain substantial metabolic activity are lacking. Unlike stationary-phase (SP) batch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33699cd627e638277f81c1e405fc424d
https://research.vu.nl/en/publications/4cb99d60-f929-440b-9f31-2239e21b9bb5

Toward pectin fermentation by Saccharomyces cerevisiae: Expression of the first two steps of a bacterial pathway for d-galacturonate metabolism

Autor: Marijke A. H. Luttik, Jack T. Pronk, Roland J. Siezen, Antonius J. A. van Maris, Eline H. Huisjes, Dieu H.N. Dang, Marinka J. H. Almering, Markus M.M. Bisschops, Michiel Kleerebezem

Publikováno v: Journal of Biotechnology, 162(2-3), 303-310
Journal of Biotechnology 162 (2012) 2-3

Saccharomyces cerevisiae cannot metabolize d-galacturonate, an important monomer of pectin. Use of S. cerevisiae for production of ethanol or other compounds of interest from pectin-rich feedstocks therefore requires introduction of a heterologous pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0eb641cebabc4e35c4520ce9a74b48
https://doi.org/10.1016/j.jbiotec.2012.10.003