Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Markus M. Hilscher"'
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106895- (2023)
Nicotinic acetylcholine receptors (nAChRs) play crucial roles in various human disorders, with the α7, α4, α6, and α3-containing nAChR subtypes extensively studied in relation to conditions such as Alzheimer's disease, Parkinson's disease, nicoti
Externí odkaz:
https://doaj.org/article/a7feb31c21b24e8fbd9ec30a37d0053a
Autor:
Renza Spelat, Federico Ferro, Paolo Contessotto, Amal Aljaabary, Sergio Martin-Saldaña, Chunsheng Jin, Niclas G. Karlsson, Maura Grealy, Markus M. Hilscher, Fulvio Magni, Clizia Chinello, Michelle Kilcoyne, Abhay Pandit
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Transcriptomic and proteomic analyses reveal that glycosylation and carbohydrate metabolism are central processes in heart regeneration in zebrafish, including a shift from OXPHOS to glycolysis seven days after injury.
Externí odkaz:
https://doaj.org/article/60800cb8f5ec42a897241778790cb149
Autor:
Markus M. Hilscher, Christoffer Mattsson Langseth, Petra Kukanja, Chika Yokota, Mats Nilsson, Gonçalo Castelo-Branco
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Oligodendrocytes are glial cells that support and insulate axons in the central nervous system through the production of myelin. Oligodendrocytes arise throughout embryonic and early postnatal development from oligodendrocyte prec
Externí odkaz:
https://doaj.org/article/8ebec61e086345adbd3180bca6c5fb7d
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Background The dorsal cochlear nucleus (DCN) is a region known to integrate somatosensory and auditory inputs and is identified as a potential key structure in the generation of phantom sound perception, especially noise-induced tinnitus. Ye
Externí odkaz:
https://doaj.org/article/318ad91349ed4e8b8071b4b33a9c6260
Autor:
Christoffer Mattsson Langseth, Daniel Gyllborg, Jeremy A. Miller, Jennie L. Close, Brian Long, Ed S. Lein, Markus M. Hilscher, Mats Nilsson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Langseth et al. present cell type maps of human cortical tissue sections and show an efficient and robust workflow to accurately resolve anatomical organization of human brain tissue.
Externí odkaz:
https://doaj.org/article/d4a49f5133b340d09b4efa394b9d61dd
Autor:
Elisa M. Floriddia, Tânia Lourenço, Shupei Zhang, David van Bruggen, Markus M. Hilscher, Petra Kukanja, João P. Gonçalves dos Santos, Müge Altınkök, Chika Yokota, Enric Llorens-Bobadilla, Sara B. Mulinyawe, Mário Grãos, Lu O. Sun, Jonas Frisén, Mats Nilsson, Gonçalo Castelo-Branco
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The oligodendrocyte lineage is known for its transcriptional heterogeneity, but the functional consequences of this are unclear. Here, the authors show that distinct populations of mature oligodendrocytes have spatial preferences in the brain and spi
Externí odkaz:
https://doaj.org/article/ece367487961471eb842a80b9dcd6fef
Autor:
Gabriele Partel, Markus M. Hilscher, Giorgia Milli, Leslie Solorzano, Anna H. Klemm, Mats Nilsson, Carolina Wählby
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Neuroanatomical compartments of the mouse brain are identified and outlined mainly based on manual annotations of samples using features related to tissue and cellular morphology, taking advantage of publicly available reference a
Externí odkaz:
https://doaj.org/article/d8c415f033614600b74b6a6e8c129f0a
Autor:
Katarína Tiklová, Åsa K. Björklund, Laura Lahti, Alessandro Fiorenzano, Sara Nolbrant, Linda Gillberg, Nikolaos Volakakis, Chika Yokota, Markus M. Hilscher, Thomas Hauling, Fredrik Holmström, Eliza Joodmardi, Mats Nilsson, Malin Parmar, Thomas Perlmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Midbrain dopamine (mDA) neurons are significantly associated with Parkinson’s disease and yet there is no systematic molecular classification of these heterogenous group of cells. Here authors use single cell RNA sequencing of isolated mouse neuron
Externí odkaz:
https://doaj.org/article/fb22d9e2478a422ebc121e8f033474f4
Autor:
Jessica Alves de Medeiros Araújo, Markus M. Hilscher, Diego Marques-Coelho, Daiane C. F. Golbert, Deborah A. Cornelio, Silvia R. Batistuzzo de Medeiros, Richardson N. Leão, Marcos R. Costa
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Reprogramming of somatic cells into induced pluripotent stem cells (iPS) or directly into cells from a different lineage, including neurons, has revolutionized research in regenerative medicine in recent years. Mesenchymal stem cells are good candida
Externí odkaz:
https://doaj.org/article/5abe809c858947db8371abbee89fb78f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Central neurons express a variety of neuronal types and ion channels that promote firing heterogeneity among their distinct neuronal populations. Action potential (AP) phasic firing, produced by low-threshold voltage activated potassium currents (VAK
Externí odkaz:
https://doaj.org/article/57c3284aada048dfa8c5650cc8bf8b55