Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Markus M Simon"'
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63437 (2013)
Many pathogenic microorganisms express fibronectin-binding molecules that facilitate their adherence to the extracellular matrix and/or entry into mammalian cells. We have previously described a Borrelia recurrentis gene, cihC that encodes a 40-kDa s
Externí odkaz:
https://doaj.org/article/cdeec34e64924bada816146e272bc927
Autor:
Sonja Grosskinsky, Melanie Schott, Christiane Brenner, Sally J Cutler, Markus M Simon, Reinhard Wallich
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 6, p e698 (2010)
The spirochete Borrelia recurrentis is the causal agent of louse-borne relapsing fever and is transmitted to humans by the infected body louse Pediculus humanus. We have recently demonstrated that the B. recurrentis surface receptor, HcpA, specifical
Externí odkaz:
https://doaj.org/article/bdaaf9e04527456d9a9b7490885a89cd
Autor:
Julián Pardo, Eva María Gálvez, Aulikki Koskinen, Markus M Simon, Mario Lobigs, Matthias Regner, Arno Müllbacher
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7512 (2009)
BACKGROUND: Ectromelia virus is a natural mouse pathogen, causing mousepox. The cytotoxic T (Tc) cell granule serine-protease, granzyme B, is important for its control, but the underlying mechanism is unknown. Using ex vivo virus immune Tc cells, we
Externí odkaz:
https://doaj.org/article/65498792f83d4665b5297cf371e14c8d
Autor:
Sonja Grosskinsky, Melanie Schott, Christiane Brenner, Sally J Cutler, Peter Kraiczy, Peter F Zipfel, Markus M Simon, Reinhard Wallich
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4858 (2009)
Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates. Here we identify for the fi
Externí odkaz:
https://doaj.org/article/1eabcba06ef24a34aed47b994fb2dcad
Autor:
Laura Comas, Christopher J. Froelich, Praxedis Martin, Cheikh Menaa, Markus M. Simon, Llipsy Santiago, Eva M. Galvez, Stuart M. Sprague, Luis Martínez-Lostao, Sunil S. Metkar, Cem Gabay, Paula Jaime-Sánchez, Erica Esser, Nadina Erill, Sri Raja, Maykel Arias, Julián Pardo, Victor Gonzalez-Rumayor
Publikováno v:
Arthritis & Rheumatology. 69:320-334
Objective Granzyme A (GzmA) levels are elevated in the plasma and synovium of patients with rheumatoid arthritis (RA), suggesting involvement of this protease in the pathogenesis of the disease. GzmA contributes to sepsis by regulating the production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86163943d1eece3b7045b6fbe5a47c1
https://doi.org/10.1002/art.39857
https://doi.org/10.1002/art.39857
Autor:
Weimin Zhong, Lise Gern, Markus M. Simon, Pierre Hauser, Christiane Brenner, Peter J. Nielsen, Reinhard Wallich, Michael D. Kramer
Plasmid DNA encoding the outer surface lipoprotein A (OspA) of Borrelia burgdorferi under the control of either strong eukaryotic/viral or its own bacterial promoter was injected intramuscularly (m. tibialis anterior) or intradermally into BALB/c and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366181c216f42bab4a6941fce561a766
http://doc.rero.ch/record/278771/files/Simon_M.-Protective_20170210152121-NR.pdf
http://doc.rero.ch/record/278771/files/Simon_M.-Protective_20170210152121-NR.pdf
Mice were infected with Borrelia burgdorferi by infection via Ixodes ricinus and experimental inoculation to determine whether transmission rates of spirochetes and antibody responses are influenced. Mice infected by the natural route were substantia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c1a9294bed57e6468efda05b80b1ac
http://doc.rero.ch/record/278755/files/Gern_L.-_Mode_of_Inoculation_20170209134349-HK.pdf
http://doc.rero.ch/record/278755/files/Gern_L.-_Mode_of_Inoculation_20170209134349-HK.pdf
Publikováno v:
European Journal of Immunology. 43:3209-3218
In this study, we report that cytoplasmic granules from in vivo and in vitro derived mouse mast cells (MCs) contain active granzyme B (gzmB) and caspase-3, which is consistent with recent findings. Studying WT and gzmB-deficient mice, we observed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f7edea79aa54fbf54741c225567cdba
https://doi.org/10.1002/eji.201343941
https://doi.org/10.1002/eji.201343941
Autor:
Christopher J. Froelich, Reinhard Wallich, Christoph Borner, Lars T. Joeckel, Sunil S. Metkar, Markus M. Simon
Publikováno v:
Journal of Virology. 86:8713-8719
The T cell granule exocytosis pathway is essential to control hepatotropic lymphocytic choriomeningitis virus strain WE (LCMV-WE) but also contributes to the observed pathology in mice. Although effective antiviral T cell immunity and development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5aaca85d3f0eb79a8da06e4ad15cb1
https://doi.org/10.1128/jvi.00682-12
https://doi.org/10.1128/jvi.00682-12
Autor:
Joseph A. Trapani, Guy S. Salvesen, Markus M. Simon, Sunil S. Metkar, Julián Pardo, Gregor Anderluh
Publikováno v:
Cell death and differentiation. 23(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedfb05e75e4e2ce6503db19de4afd9e
https://pubmed.ncbi.nlm.nih.gov/26639556
https://pubmed.ncbi.nlm.nih.gov/26639556