Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Markus M Heimesaat"'
Autor:
Sandra-Maria Wienhold, Mario Macrì, Geraldine Nouailles, Kristina Dietert, Corinne Gurtner, Achim D Gruber, Markus M Heimesaat, Jasmin Lienau, Fabian Schumacher, Burkhard Kleuser, Bastian Opitz, Norbert Suttorp, Martin Witzenrath, Holger C Müller-Redetzky
Publikováno v:
Critical Care, Vol 22, Iss 1, Pp 1-12 (2018)
Abstract Background Antibiotic exposure alters the microbiota, which can impact the inflammatory immune responses. Critically ill patients frequently receive antibiotic treatment and are often subjected to mechanical ventilation, which may induce loc
Externí odkaz:
https://doaj.org/article/77a19fd40e1b4921aa74b0a9ef736f36
Autor:
Angelina Kraski, Paweł Migdał, Robert Klopfleisch, Clara Räckel, Jutta Sharbati, Markus M. Heimesaat, Thomas Alter, Carlos Hanisch, Greta Gölz, Ralf Einspanier, Soroush Sharbati
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background 3D cell culture models have recently garnered increasing attention for replicating organ microarchitecture and eliciting in vivo-like responses, holding significant promise across various biological disciplines. Broadly, 3D cell c
Externí odkaz:
https://doaj.org/article/c3b6302cf7f74b3dbcfc7457b80508e4
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176144 (2017)
BACKGROUND:Within seven days following peroral high dose infection with Toxoplasma gondii susceptible conventionally colonized mice develop acute ileitis due to an underlying T helper cell (Th) -1 type immunopathology. We here addressed whether mice
Externí odkaz:
https://doaj.org/article/46f58e4e20a24f419e03ef1fb6106b51
Autor:
Stefan Bereswill, Marie E Alutis, Ursula Grundmann, André Fischer, Ulf B Göbel, Markus M Heimesaat
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158020 (2016)
BACKGROUND:Human Campylobacter jejuni infections are progressively rising worldwide. Information about the molecular mechanisms underlying campylobacteriosis, however, are limited. In the present study we investigated whether cytokines such as IL-23,
Externí odkaz:
https://doaj.org/article/2762f9d3d7854ca59e3ffde02a66a8d0
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159685 (2016)
Only limited information is available about the immunopathogenic properties of Arcobacter infection in vivo. Therefore, we performed a meta-analysis of published data in murine infection models to compare the pathogenic potential of Arcobacter butzle
Externí odkaz:
https://doaj.org/article/12b3048f0b244b229627ee62b68bdba4
Autor:
Patrick J. Dörner, Harithaa Anandakumar, Ivo Röwekamp, Facundo Fiocca Vernengo, Belén Millet Pascual-Leone, Marta Krzanowski, Josua Sellmaier, Ulrike Brüning, Raphaela Fritsche-Guenther, Lennart Pfannkuch, Florian Kurth, Miha Milek, Vanessa Igbokwe, Ulrike Löber, Birgitt Gutbier, Markus Holstein, Gitta Anne Heinz, Mir-Farzin Mashreghi, Leon N. Schulte, Ann-Brit Klatt, Sandra Caesar, Sandra-Maria Wienhold, Stefan Offermanns, Matthias Mack, Martin Witzenrath, Stefan Jordan, Dieter Beule, Jennifer A. Kirwan, Sofia K. Forslund, Nicola Wilck, Hendrik Bartolomaeus, Markus M. Heimesaat, Bastian Opitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Hospital-acquired pneumonia (HAP) is associated with high mortality and costs, and frequently caused by multidrug-resistant (MDR) bacteria. Although prior antimicrobial therapy is a major risk factor for HAP, the underlying mechanism remains
Externí odkaz:
https://doaj.org/article/41a8a643c26b41c0b66352c312b98b9b
Autor:
Greta Gölz, Gül Karadas, Marie E Alutis, André Fischer, Anja A Kühl, Angele Breithaupt, Ulf B Göbel, Thomas Alter, Stefan Bereswill, Markus M Heimesaat
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139402 (2015)
The immunopathological impact of human Arcobacter (A.) infections is under current debate. Episodes of gastroenteritis with abdominal pain and acute or prolonged watery diarrhea were reported for A. butzleri infected patients. Whereas adhesive, invas
Externí odkaz:
https://doaj.org/article/dec855cd2a4e4ba3aeec6bfb01c1571d
Autor:
Nancy A Erickson, Elisabeth E L Nyström, Lars Mundhenk, Liisa Arike, Rainer Glauben, Markus M Heimesaat, André Fischer, Stefan Bereswill, George M H Birchenough, Achim D Gruber, Malin E V Johansson
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131991 (2015)
The secreted, goblet cell-derived protein Clca1 (chloride channel regulator, calcium-activated-1) has been linked to diseases with mucus overproduction, including asthma and cystic fibrosis. In the intestine Clca1 is found in the mucus with an abunda
Externí odkaz:
https://doaj.org/article/e46b66a46cc24b94baf3b0cade046e49
Autor:
Markus M Heimesaat, Ildiko R Dunay, Silvia Schulze, André Fischer, Ursula Grundmann, Marie Alutis, Anja A Kühl, Andrea Tamas, Gabor Toth, Miklos P Dunay, Ulf B Göbel, Dora Reglodi, Stefan Bereswill
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108389 (2014)
The neuropeptide Pituitary adenylate cyclase-activating polypeptide (PACAP) plays pivotal roles in immunity and inflammation. So far, potential immune-modulatory properties of PACAP have not been investigated in experimental ileitis.Mice were peroral
Externí odkaz:
https://doaj.org/article/8316c5dfc8cb410e9b8c36cacb8d4aff
Autor:
Markus M Heimesaat, André Fischer, Rita Plickert, Tobias Wiedemann, Christoph Loddenkemper, Ulf B Göbel, Stefan Bereswill, Gabriele Rieder
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100362 (2014)
BACKGROUND: Gastrointestinal (GI) inflammation in mice and men are frequently accompanied by distinct changes of the GI microbiota composition at sites of inflammation. Helicobacter (H.) pylori infection results in gastric immunopathology accompanied
Externí odkaz:
https://doaj.org/article/81295ed80cce4a8b9c8dd1d330564478