Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Markus Krauß"'
Autor:
Markus Krauss, Ute Hofmann, Clemens Schafmayer, Svitlana Igel, Jan Schlender, Christian Mueller, Mario Brosch, Witigo von Schoenfels, Wiebke Erhart, Andreas Schuppert, Michael Block, Elke Schaeffeler, Gabriele Boehmer, Linus Goerlitz, Jan Hoecker, Joerg Lippert, Reinhold Kerb, Jochen Hampe, Lars Kuepfer, Matthias Schwab
Publikováno v:
npj Systems Biology and Applications, Vol 3, Iss 1, Pp 1-11 (2017)
Systems pharmacology: predicting population pharmacokinetics in silico Physiologically based modeling together with Bayesian statistics allows the prediction of drug pharmacokinetics in specific patient populations. An interdisciplinary group of clin
Externí odkaz:
https://doaj.org/article/ec1cdb4109a643779b3939519f2d8816
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139423 (2015)
Interindividual variability in anatomical and physiological properties results in significant differences in drug pharmacokinetics. The consideration of such pharmacokinetic variability supports optimal drug efficacy and safety for each single indivi
Externí odkaz:
https://doaj.org/article/352d4df5599c44858558f34e7036fb7e
Autor:
Lars Ole Schwen, Markus Krauss, Christoph Niederalt, Felix Gremse, Fabian Kiessling, Andrea Schenk, Tobias Preusser, Lars Kuepfer
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 3, p e1003499 (2014)
The liver is the central organ for detoxification of xenobiotics in the body. In pharmacokinetic modeling, hepatic metabolization capacity is typically quantified as hepatic clearance computed as degradation in well-stirred compartments. This is an a
Externí odkaz:
https://doaj.org/article/637b5a124ad34fafbab5f8e7da8b4d1b
Autor:
Markus Krauss, Stephan Schaller, Steffen Borchers, Rolf Findeisen, Jörg Lippert, Lars Kuepfer
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 10, p e1002750 (2012)
Cellular metabolism continuously processes an enormous range of external compounds into endogenous metabolites and is as such a key element in human physiology. The multifaceted physiological role of the metabolic network fulfilling the catalytic con
Externí odkaz:
https://doaj.org/article/1f97e6075a66464f9c52b8701d1502af
Autor:
Christian Lilge, Markus R. Scholz, Robin Heß, Klaus Schilling, Michael Fritscher, Markus Krauß, Florian Leutert
Publikováno v:
Procedia Computer Science. 180:150-161
The term Industry 4.0 – manufacturing with exploitation of digital technologies – comprises several challenging topics, among others intuitive machine programming, advanced maintenance-enabling technologies as well as flexible logistics. This pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a669038a761f4e25911def2f8b742a7
https://doi.org/10.1016/j.procs.2021.01.138
https://doi.org/10.1016/j.procs.2021.01.138
Publikováno v:
IFAC-PapersOnLine. 52:7-12
This paper shows the special needs of tele maintenance regarding Quality of Service (QoS). Then measurements of real-world communication links which are used by industry are presented and analyzed. Based on these results and the requirements of servi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11f257a87fdd25b238d8308b3e2b5aca
https://doi.org/10.1016/j.ifacol.2019.12.365
https://doi.org/10.1016/j.ifacol.2019.12.365
Publikováno v:
IFAC-PapersOnLine. 52:1-6
In this contribution, a data-driven approach towards the prediction of maintenance for the critical component of an injection molding machine is presented. We present our path from exploring and cleaning the data towards the implementation of a predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2804b0a0964c44ab869495a031ecf1d
https://doi.org/10.1016/j.ifacol.2019.12.364
https://doi.org/10.1016/j.ifacol.2019.12.364
Publikováno v:
IFAC-PapersOnLine. 51:447-452
In this contribution we present a model based approach towards predictive maintenance of the hydraulic pump of an injection-moulding machine for a system that remains in production. We present a methodology to iteratively gain a detailed understandin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10b9a34624a9ccb4a17d81c3ccf1599
https://doi.org/10.1016/j.ifacol.2018.08.346
https://doi.org/10.1016/j.ifacol.2018.08.346
Publikováno v:
IFAC-PapersOnLine. 50:11239-11244
This paper puts a finer point to remote telemaintenance with asynchronous access to an industrial production plant and its data. At first, the condition monitoring records the data from the industrial manipulator and transfers it via the Internet to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dcaffe7b27233a77279b96a142253fa
https://doi.org/10.1016/j.ifacol.2017.08.1604
https://doi.org/10.1016/j.ifacol.2017.08.1604
Autor:
Michaela Meyer, Stefan Willmann, Kirstin Thelen, Markus Krauss, Thomas Eissing, Ulrich Jaehde, Jan-Frederik Schlender
Publikováno v:
Clinical Pharmacokinetics
Background Because of the vulnerability and frailty of elderly adults, clinical drug development has traditionally been biased towards young and middle-aged adults. Recent efforts have begun to incorporate data from paediatric investigations. Neverth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3e6ee332632750d676901559397fe3
https://doi.org/10.1007/s40262-016-0422-3
https://doi.org/10.1007/s40262-016-0422-3