Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Markus Kiel"'
Autor:
M. Gunther, Michael R. Doran, Kerry Atkinson, Gary Brooke, Nicholas E. Timmins, Celena Heazlewood, Markus Kiel
Publikováno v:
Biotechnology and Bioengineering
Mesenchymal stem cells (MSC) are emerging as a leading cellular therapy for a number of diseases. However, for such treatments to become available as a routine therapeutic option, efficient and cost-effective means for industrial manufacture of MSC a
Publikováno v:
International Journal for Parasitology. 37:1419-1429
Gastrointestinal nematode infections of livestock animals are prevalent and costly problems worldwide. Currently, infections are controlled by anthelmintic chemicals but increasing drug resistance has prompted research interest to shift towards alter
Autor:
Mario Kuttke, Dominika Hromadová, Ceren Yildirim, Julia S. Brunner, Andrea Vogel, Hannah Paar, Sophie Peters, Maria Weber, Melanie Hofmann, Martina Kerndl, Markus Kieler, Hannes Datler, Laszlo Musiejovsky, Manuel Salzmann, Michaela Lang, Klara Soukup, Angela Halfmann, Omar Sharif, Gernot Schabbauer
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Aberrant innate immune responses to the gut microbiota are causally involved in the pathogenesis of inflammatory bowel diseases (IBD). The exact triggers and main signaling pathways activating innate immune cells and how they modulate adaptive immuni
Externí odkaz:
https://doaj.org/article/8fc40d72faab43029d584838fb78452a
Autor:
Julia S. Brunner, Loan Vulliard, Melanie Hofmann, Markus Kieler, Alexander Lercher, Andrea Vogel, Marion Russier, Johanna B. Brüggenthies, Martina Kerndl, Victoria Saferding, Birgit Niederreiter, Alexandra Junza, Annika Frauenstein, Carina Scholtysek, Yohei Mikami, Kristaps Klavins, Gerhard Krönke, Andreas Bergthaler, John J. O’Shea, Thomas Weichhart, Felix Meissner, Josef S. Smolen, Paul Cheng, Oscar Yanes, Jörg Menche, Peter J. Murray, Omar Sharif, Stephan Blüml, Gernot Schabbauer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Multinucleated giant cells (MGCs) are important in the pathogenesis of various diseases. Here, the authors demonstrate that extracellular presence of the amino acid arginine is required for MGC formation and metabolism, suggesting a translational imp
Externí odkaz:
https://doaj.org/article/28055bd4c7454a9b869483a12530bfc2
Autor:
Daniela Bianconi, Merima Herac, Daniel Spies, Markus Kieler, Robert Brettner, Matthias Unseld, Katrin Fürnkranz, Barbara Famler, Margit Schmeidl, Christoph Minichsdorfer, Christoph Zielinski, Gerwin Heller, Gerald W. Prager
Publikováno v:
Translational Oncology, Vol 12, Iss 1, Pp 15-23 (2019)
Stratification of patients with pancreatic ductal adenocarcinoma (PDAC) remains a key challenge in the field of clinical oncology. No predictive biomarkers have yet been found for any available treatment options. Previously, we identified SERPINB7 as
Externí odkaz:
https://doaj.org/article/8701ba38765146da920627c33d66bcbf
Autor:
Daniela Bianconi, Merima Herac, Florian Posch, Margit Schmeidl, Matthias Unseld, Markus Kieler, Robert Brettner, Leonhard Müllauer, Jakob Riedl, Armin Gerger, Werner Scheithauer, Gerald Prager
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Targeted therapies offer novel opportunities to explore biomarkers based on their mode of action. Taking this into consideration, we evaluated six angiogenesis-related proteins as potential predictive biomarkers, which expression might pr
Externí odkaz:
https://doaj.org/article/05efbbfb282e4300bf7b30ae3944d7a3
Autor:
Lea Kum, Alexander Friedrich, Markus Kieler, Elias Meyer, Petar Popov, Paul Kössler, Anna Kitta, Feroniki Adamidis, Raimund Oberle, Eva Katharina Masel, Matthias Unseld
Publikováno v:
Nutrients, Vol 14, Iss 4, p 769 (2022)
Background. Parenteral nutrition (PN) is frequently administered in palliative care patients suffering from cachexia. The evidence regarding the use of PN in terminally ill patients is scarce. Routine laboratory parameters might help to decide whethe
Externí odkaz:
https://doaj.org/article/fb76bc41128445c485c1f8bc995c8ba0
Autor:
Daniela Bianconi, Gerwin Heller, Daniel Spies, Merima Herac, Andreas Gleiss, Sandra Liebmann-Reindl, Matthias Unseld, Markus Kieler, Werner Scheithauer, Berthold Streubel, Christoph C. Zielinski, Gerald W. Prager
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Pancreatic cancer is a dismal disease with a mortality rate almost similar to its incidence rate. To date, there are neither validated predictive nor prognostic biomarkers for this lethal disease. Thus, the aim of the present study was to re
Externí odkaz:
https://doaj.org/article/ad7dec37c3fb48049fe3aced16deae55
Autor:
Christoph C Zielinski, Markus Kieler, Matthias Unseld, Daniela Bianconi, Fredrik Waneck, Robert Mader, Fritz Wrba, Thorsten Fuereder, Philipp Staber, Walter Berger, Maria Sibilia, Stephan Polterauer, Leonhard Müllauer, Gerald W Prager
Publikováno v:
ESMO Open, Vol 4, Iss 4 (2019)
Background High-throughput genomic profiling of tumour specimens facilitates the identification of individual actionable mutations which could be used for individualised targeted therapy. This approach is becoming increasingly more common in the clin
Externí odkaz:
https://doaj.org/article/a302d32bee064beda7f655065565cb61
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Nanoliposomal irinotecan (nal-IRI) plus 5-fluorouracil/leucovorin (5-FU/LV) is a novel treatment option for gemcitabine-pretreated metastatic pancreatic adenocarcinoma (PAC) patients, but real-world evidence is rare. Our aim was to determ
Externí odkaz:
https://doaj.org/article/2dd64dd34210440583748f53988399b4