Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Markus Kügler"'
Autor:
Michael Schwenkert, Christoph Stein, Georg H. Fey, Andreas Mackensen, Fuat Oduncu, Markus Kügler, Kristin Mentz, Bernhard Stockmeyer, Ingo Schubert, Christian Kellner, Heiko Singer, Domenica Saul
Publikováno v:
British Journal of Haematology. 150:574-586
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508f4f01b614ad3fa0197800eb643ee6
https://doi.org/10.1111/j.1365-2141.2010.08300.x
https://doi.org/10.1111/j.1365-2141.2010.08300.x
Autor:
Michael Schwenkert, Matthias Peipp, Jan Dörrie, Katrin Birkholz, Christian Kellner, Dirk M. Nettelbeck, Niels Schaft, Georg H. Fey, Beatrice Schuler-Thurner, Eckhart Kämpgen, Markus Kügler, Soldano Ferrone, Michael Schwemmlein
Publikováno v:
Melanoma Research. 18:73-84
A recombinant immunotoxin was constructed by fusing a single chain fragment variable antibody fragment, specific for the melanoma-associated chondroitin sulfate proteoglycan (MCSP), to a truncated variant of Pseudomonas exotoxin A (ETA'), carrying a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344c30750788253a80726628bef80453
https://doi.org/10.1097/cmr.0b013e3282f7c8f9
https://doi.org/10.1097/cmr.0b013e3282f7c8f9
Autor:
Ingo Schubert, Markus Kügler, Michael Schwenkert, Georg H. Fey, Andreas Mackensen, Fuat Oduncu, Domenica Saul, Christoph Stein, Bernhard Stockmeyer, Christian Berens, Christian Kellner
To test the hypothesis that dual-targeting confers the novel ability of selective binding to antigen double-positive over antigen single-positive cells, a single-chain triplebody (sctb), HLA-ds16-hu19, was produced and characterized. The molecule car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9880ce136b76dd521077c03737ac9bf9
https://europepmc.org/articles/PMC3338940/
https://europepmc.org/articles/PMC3338940/
Autor:
Ingo Schubert, Andreas Mackensen, Michael Schwenkert, Domenica Saul, Christoph Stein, Kristin Mentz, Wolfgang Hillen, Georg H. Fey, Christian Kellner, Bernhard Stockmeyer, Heiko Singer, Markus Kügler
A single-chain triplebody (sctb) 33-ds16-ds19 comprising two distal single-chain Fv fragments (scFvs) specific for the lymphoid antigen CD19 and the myeloid antigen CD33 flanking a central scFv specific for CD16, which is the low affinity Fc-receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1829224576db9d26b73db6669177fb5e
https://europepmc.org/articles/PMC3038008/
https://europepmc.org/articles/PMC3038008/
Autor:
Markus, Kügler, Christoph, Stein, Christian, Kellner, Kristin, Mentz, Domenica, Saul, Michael, Schwenkert, Ingo, Schubert, Heiko, Singer, Fuat, Oduncu, Bernhard, Stockmeyer, Andreas, Mackensen, Georg H, Fey
Publikováno v:
British journal of haematology. 150(5)
Two trivalent constructs consisting of single-chain Fv antibody fragments (scFvs) specific for the interleukin-3 receptor alpha chain (CD123), CD33 and the Fcgamma-receptor III (CD16) were designed and characterized for the elimination of acute myelo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bd22405b01fa14cca6888075dd8ad08
https://pubmed.ncbi.nlm.nih.gov/20636437
https://pubmed.ncbi.nlm.nih.gov/20636437
Autor:
Markus Kügler, Georg H. Fey, Nina Reiff, Andreas Mackensen, Christoph Stein, Bernhard Stockmeyer, Kristin Mentz, Michael Schwenkert, Christian Kellner
Publikováno v:
British journal of haematology. 148(6)
Four new single-chain Fv antibody fragments (scFvs) specific for the human leucocyte surface antigen CD123 (interleukin-3 receptor alpha) were generated to achieve preferential targeting of leukaemia stem cells (LSCs) in acute myeloid leukaemia (AML)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c492541d758d728c9508bbc0840f0106
https://pubmed.ncbi.nlm.nih.gov/20064159
https://pubmed.ncbi.nlm.nih.gov/20064159
Autor:
Michael Schwenkert, Thomas Huber, Markus Kügler, Lena Vockentanz, Svava K. Wetzel, Georg H. Fey, Christoph Stein, Andreas Plückthun, Domenica Saul, Oliver Scholz, Annemarie Honegger
A single-chain Fv (scFv) fragment derived from the murine antibody 4G7, specific for human lymphocyte CD19, was engineered for stability and expression in Escherichia coli in view of future use as a therapeutic protein. We compared two orthogonal kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0239829a95e81e94183d3d2da41da678
https://www.zora.uzh.ch/id/eprint/20980/
https://www.zora.uzh.ch/id/eprint/20980/
Publikováno v:
Ökologisches Entwicklungspotential der Bergbaufolgelandschaften im Niederlausitzer Braunkohlerevier ISBN: 9783519003212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e6042c8c696190449f666470ea7bfb
https://doi.org/10.1007/978-3-322-87179-4_22
https://doi.org/10.1007/978-3-322-87179-4_22
Autor:
Markus Kügler, Christoph Stein, Michael Schwenkert, Domenica Saul, Lena Vockentanz, Thomas Huber, Svava K. Wetzel, Oliver Scholz, Andreas Plückthun, Annemarie Honegger, Georg H. Fey
Publikováno v:
PEDS: Protein Engineering, Design & Selection; Mar2009, Vol. 22 Issue 3, p135-135, 1p
Autor:
Schwenkert, Michael, Birkholz, Katrin, Schwemmlein, Michael, Kellner, Christian, Kügler, Markus, Peipp, Matthias, Nettelbeck, Dirk M., Schuler-Thurner, Beatrice, Schaft, Niels, Dörrie, Jan, Ferrone, Soldano, Kämpgen, Eckhart, Fey, Georg H.
Publikováno v:
Melanoma Research; Apr2008, Vol. 18 Issue 2, p73-84, 12p