Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Markus Körbel"'
Autor:
Edward Jenkins, Markus Körbel, Caitlin O’Brien-Ball, James McColl, Kevin Y. Chen, Mateusz Kotowski, Jane Humphrey, Anna H. Lippert, Heather Brouwer, Ana Mafalda Santos, Steven F. Lee, Simon J. Davis, David Klenerman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
T cells can use TCR on microvilli to interact with peptide-MHC (pMHC) complexes on antigen presenting cells. Here the authors characterise how T cells use microvilli to interrogate reconstituted membranes for pMHC complexes and how this is regulated
Externí odkaz:
https://doaj.org/article/e163cebf0d034cc0b49fca7e959be290
An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy
Autor:
Jeff Y.L. Lam, Yunzhao Wu, Eleni Dimou, Ziwei Zhang, Matthew R. Cheetham, Markus Körbel, Zengjie Xia, David Klenerman, John S.H. Danial
Publikováno v:
Biophysical Reports, Vol 2, Iss 1, Pp 100044- (2022)
Super-resolution microscopy allows complex biological assemblies to be observed with remarkable resolution. However, the presence of uneven Gaussian-shaped illumination hinders its use in quantitative imaging or high-throughput assays. Methods develo
Externí odkaz:
https://doaj.org/article/3a39a673eaba4796882277f38133c030
Autor:
Ezra Bruggeman, Oumeng Zhang, Lisa-Maria Needham, Markus Körbel, Sam Daly, Matthew Cheetham, Ruby Peters, Tingting Wu, Andrey S. Klymchenko, Simon J. Davis, Ewa K. Paluch, David Klenerman, Matthew D. Lew, Kevin O’Holleran, Steven F. Lee
Current methods for single-molecule orientation localization microscopy (SMOLM) require optical setups and algorithms that can be prohibitively slow and complex, limiting the widespread adoption for biological applications. We present POLCAM, a simpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::308abc94bce8c426918c4c87d716fa41
https://doi.org/10.1101/2023.02.07.527479
https://doi.org/10.1101/2023.02.07.527479
Autor:
Caitlin O'Brien-Ball, Simon J. Davis, David Klenerman, Ana Filipa L.O.M. Santos, Kevin Y. Chen, Anna Lippert, Edward Jenkins, Jemma McBride, Markus Körbel, Nicole Ashman, Aleks Ponjavic
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Despite the success of T cell–redirecting immunotherapies for blood cancers, toxic, off-target side effects prevent their safe application to other diseases. Part of the challenge lies in our incomplete understanding of T cell receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da572062ccf19f99faf634d56f90e823
https://doi.org/10.1073/pnas.2024250118
https://doi.org/10.1073/pnas.2024250118
Autor:
Markus Körbel, Edward Jenkins, James T. McColl, Caitlin O'Brien-Ball, Anna H. Lippert, Ana Mafalda Santos, Steven F. Lee, Simon J. Davis, David Klenerman
Publikováno v:
Biophysical Journal. 121:150a-151a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf657bd8cb5c467ce52eb7d41796ceb
https://doi.org/10.1016/j.bpj.2021.11.1976
https://doi.org/10.1016/j.bpj.2021.11.1976
Autor:
Gerhard F. Ecker, Markus Körbel, Riccardo Martini, Doris A. Schuetz, Thomas Seidel, Thierry Langer, Arthur Garon
Publikováno v:
Journal of chemical theory and computation. 14(9)
In the absence of experimentally derived, three-dimensional structures of receptors in complex with active ligands, it is of high value to be able to gain knowledge about energetically favorable interaction sites solely from the structure of the rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c09b41bef370fcceaf3a9b1cf9e68e
https://pubmed.ncbi.nlm.nih.gov/30075621
https://pubmed.ncbi.nlm.nih.gov/30075621