Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Markus J. Tamás"'
Autor:
Esin Isik, Çiğdem Balkan, Vivien Karl, Hüseyin Çağlar Karakaya, Sansan Hua, Sebastien Rauch, Markus J. Tamás, Ahmet Koc
Publikováno v:
MicrobiologyOpen, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract Arsenic is a toxic metalloid that affects human health by causing numerous diseases and by being used in the treatment of acute promyelocytic leukemia. Saccharomyces cerevisiae (budding yeast) has been extensively utilized to elucidate the m
Externí odkaz:
https://doaj.org/article/43318f48daed42dd95c04344a0fa14ca
Autor:
Emma Lorentzon, Istvan Horvath, Ranjeet Kumar, Joana Isabel Rodrigues, Markus J. Tamás, Pernilla Wittung-Stafshede
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 21, p 11455 (2021)
Exposure to heavy metals, including arsenic and cadmium, is associated with neurodegenerative disorders such as Parkinson’s disease. However, the mechanistic details of how these metals contribute to pathogenesis are not well understood. To search
Externí odkaz:
https://doaj.org/article/93304e0595a04fb29a3e1ab124338036
Autor:
Gerd Patrick Bienert, Markus J. Tamás
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Externí odkaz:
https://doaj.org/article/9492347229ae4164a259512e7e296178
Publikováno v:
Biology Open, Vol 3, Iss 10, Pp 913-923 (2014)
Protein aggregation is a widespread phenomenon in cells and associated with pathological conditions. Yet, little is known about the rules that govern protein aggregation in living cells. In this study, we biochemically isolated aggregation-prone prot
Externí odkaz:
https://doaj.org/article/41b8f893037d495db433da0b4856b050
Publikováno v:
Biomolecules, Vol 4, Iss 1, Pp 252-267 (2014)
While the toxicity of metals and metalloids, like arsenic, cadmium, mercury, lead and chromium, is undisputed, the underlying molecular mechanisms are not entirely clear. General consensus holds that proteins are the prime targets; heavy metals inter
Externí odkaz:
https://doaj.org/article/df564839e9854234b01b6a375a35661c
Publikováno v:
FEBS Letters.
Autor:
Yves Schulze, Payam Ghiaci, Liqian Zhao, Marc Biver, Jonas Warringer, Montserrat Filella, Markus J Tamás
Publikováno v:
Metallomics.
Aluminium, gallium, and indium are group 13 metals with similar chemical and physical properties. While aluminium is one of the most abundant elements in the Earth's crust, gallium and indium are present only in trace amounts. However, the increased
Publikováno v:
Nucleic Acids Research
Activator proteins 1 (AP-1) comprise one of the largest families of eukaryotic basic leucine zipper transcription factors. Despite advances in the characterization of AP-1 DNA-binding sites, our ability to predict new binding sites and explain how th
Autor:
Sansan, Hua, Agnieszka, Kłosowska, Joana I, Rodrigues, Gabriel, Petelski, Lidia A, Esquembre, Emma, Lorentzon, Lars F, Olsen, Krzysztof, Liberek, Markus J, Tamás
Publikováno v:
The Journal of biological chemistry. 298(12)
The poisonous metalloid arsenite induces widespread misfolding and aggregation of nascent proteins in vivo, and this mode of toxic action might underlie its suspected role in the pathology of certain protein misfolding diseases. Evolutionarily conser
Autor:
Antonia M Romero, Ewa Maciaszczyk-Dziubinska, Mandana Mombeinipour, Emma Lorentzon, Emelie Aspholm, Robert Wysocki, Markus J Tamás
Publikováno v:
FEMS Yeast Research. 22
In a high-throughput yeast two-hybrid screen of predicted coiled-coil motif interactions in the Saccharomyces cerevisiae proteome, the protein Etp1 was found to interact with the yeast AP-1-like transcription factors Yap8, Yap1 and Yap6. Yap8 plays a