Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Markus J. Herrgard"'
Autor:
Stefano Donati, Matthias Mattanovich, Pernille Hjort, Simo Abdessamad Baallal Jacobsen, Sarah Dina Blomquist, Drude Mangaard, Nicolas Gurdo, Felix Pacheco Pastor, Jérôme Maury, Rene Hanke, Markus J. Herrgård, Tune Wulff, Tadas Jakočiūnas, Lars Keld Nielsen, Douglas McCloskey
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Multi-omics datasets are becoming of key importance to drive discovery in fundamental research as much as generating knowledge for applied biotechnology. However, the construction of such large datasets is usually time-consuming and expensiv
Externí odkaz:
https://doaj.org/article/c89e1030bd6e4de38097125bb0d955c5
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3912-3919 (2023)
A long-standing goal of personalized and precision medicine is to enable accurate prediction of the outcomes of a given treatment regimen for patients harboring a disease. Currently, many clinical trials fail to meet their endpoints due to underlying
Externí odkaz:
https://doaj.org/article/3fdca938c9c1462bbd56320d057266ca
Autor:
Ariane Zutz, Louise Hamborg, Lasse Ebdrup Pedersen, Maher M. Kassem, Elena Papaleo, Anna Koza, Markus J. Herrgård, Sheila Ingemann Jensen, Kaare Teilum, Kresten Lindorff-Larsen, Alex Toftgaard Nielsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Heterologous expression of recombinant proteins often results in misfolding, aggregation and degradation. Here, we show an in vivo dual-biosensor system that simultaneously assesses protein translation and protein folding, thereby enabling rapid scre
Externí odkaz:
https://doaj.org/article/d73636bd2c4c476f86d904abfec19668
Autor:
Nathan Hillson, Mark Caddick, Yizhi Cai, Jose A. Carrasco, Matthew Wook Chang, Natalie C. Curach, David J. Bell, Rosalind Le Feuvre, Douglas C. Friedman, Xiongfei Fu, Nicholas D. Gold, Markus J. Herrgård, Maciej B. Holowko, James R. Johnson, Richard A. Johnson, Jay D. Keasling, Richard I. Kitney, Akihiko Kondo, Chenli Liu, Vincent J. J. Martin, Filippo Menolascina, Chiaki Ogino, Nicola J. Patron, Marilene Pavan, Chueh Loo Poh, Isak S. Pretorius, Susan J. Rosser, Nigel S. Scrutton, Marko Storch, Hille Tekotte, Evelyn Travnik, Claudia E. Vickers, Wen Shan Yew, Yingjin Yuan, Huimin Zhao, Paul S. Freemont
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-4 (2019)
Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research. Many biofoundries are being built and a Global Biofoundry Allia
Externí odkaz:
https://doaj.org/article/de6edd0c40ef4b9a90ff2ae779879b15
Autor:
Jonathan Dahlin, Carina Holkenbrink, Eko Roy Marella, Guokun Wang, Ulf Liebal, Christian Lieven, Dieter Weber, Douglas McCloskey, Hong-Lei Wang, Birgitta E. Ebert, Markus J. Herrgård, Lars Mathias Blank, Irina Borodina
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/25a38164400d402c857cc46f25c85428
Autor:
Nathan Hillson, Mark Caddick, Yizhi Cai, Jose A. Carrasco, Matthew Wook Chang, Natalie C. Curach, David J. Bell, Rosalind Le Feuvre, Douglas C. Friedman, Xiongfei Fu, Nicholas D. Gold, Markus J. Herrgård, Maciej B. Holowko, James R. Johnson, Richard A. Johnson, Jay D. Keasling, Richard I. Kitney, Akihiko Kondo, Chenli Liu, Vincent J. J. Martin, Filippo Menolascina, Chiaki Ogino, Nicola J. Patron, Marilene Pavan, Chueh Loo Poh, Isak S. Pretorius, Susan J. Rosser, Nigel S. Scrutton, Marko Storch, Hille Tekotte, Evelyn Travnik, Claudia E. Vickers, Wen Shan Yew, Yingjin Yuan, Huimin Zhao, Paul S. Freemont
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-2 (2019)
The original version of this Comment contained errors in the legend of Figure 2, in which the locations of the fifteenth and sixteenth GBA members were incorrectly given as ‘(15) Australian Genome Foundry, Macquarie University; (16) Australian Foun
Externí odkaz:
https://doaj.org/article/40620d862dac4b868d5d402e96beff9e
Autor:
Christian Lieven, Leander A. H. Petersen, Sten Bay Jørgensen, Krist V. Gernaey, Markus J. Herrgard, Nikolaus Sonnenschein
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Background: Genome-scale metabolic models allow researchers to calculate yields, to predict consumption and production rates, and to study the effect of genetic modifications in silico, without running resource-intensive experiments. While these mode
Externí odkaz:
https://doaj.org/article/5963a604e63c4d8dbb119352397082ca
Autor:
João Gonçalo Rocha Cardoso, Mikael Rørdam eAndersen, Markus J Herrgard, Nikolaus eSonnenschein
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 3 (2015)
Genetic variation is the motor of evolution and allows organisms to overcome the environmental challenges they encounter. It can be both beneficial and harmful in the process of engineering cell factories for the production of proteins and chemicals.
Externí odkaz:
https://doaj.org/article/17fe5679219a47b3b964cd1e43aaaacf
Autor:
Scott A, Becker, Adam M, Feist, Monica L, Mo, Gregory, Hannum, Bernhard Ø, Palsson, Markus J, Herrgard
Publikováno v:
Nature Protocols. 2:727-738
The manner in which microorganisms utilize their metabolic processes can be predicted using constraint-based analysis of genome-scale metabolic networks. Herein, we present the constraint-based reconstruction and analysis toolbox, a software package
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 3 (2015)