Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Markus Hippich"'
Autor:
Peter Achenbach, Markus Hippich, Jose Zapardiel-Gonzalo, Beate Karges, Reinhard W. Holl, Agnese Petrera, Ezio Bonifacio, Anette-G. Ziegler
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104118- (2022)
Summary: Background: Diabetes in childhood and adolescence includes autoimmune and non-autoimmune forms with heterogeneity in clinical and biochemical presentations. An unresolved question is whether there are subtypes, endotypes, or theratypes withi
Externí odkaz:
https://doaj.org/article/44c3c10a8be74adfad637a8c2b3650fc
Autor:
Ezio Bonifacio, Andreas Beyerlein, Markus Hippich, Christiane Winkler, Kendra Vehik, Michael N Weedon, Michael Laimighofer, Andrew T Hattersley, Jan Krumsiek, Brigitte I Frohnert, Andrea K Steck, William A Hagopian, Jeffrey P Krischer, Åke Lernmark, Marian J Rewers, Jin-Xiong She, Jorma Toppari, Beena Akolkar, Richard A Oram, Stephen S Rich, Anette-G Ziegler, TEDDY Study Group
Publikováno v:
PLoS Medicine, Vol 15, Iss 4, p e1002548 (2018)
BackgroundAround 0.3% of newborns will develop autoimmunity to pancreatic beta cells in childhood and subsequently develop type 1 diabetes before adulthood. Primary prevention of type 1 diabetes will require early intervention in genetically at-risk
Externí odkaz:
https://doaj.org/article/7daf435b846a44c6928e296965eb91ab
Autor:
Ezio Bonifacio, Andreas Beyerlein, Christiane Winker, Andrea K. Steck, Marian Rewers, Suna Onengut-Gumuscu, Markus Hippich, Jeffrey P. Krischer, Stephen S. Rich, Anette-G. Ziegler, Jorma Toppari, Kendra Vehik, Åke Lernmark, Jin-Xiong She, Jan Knoop, William Hagopian, Beena Akolkar, Catherine C. Robertson
Publikováno v:
Diabetes
Diabetes 68, 847-857 (2019)
Diabetes 68, 847-857 (2019)
The risk for autoimmunity and subsequently type 1 diabetes is 10-fold higher in children with a first-degree family history of type 1 diabetes (FDR children) than in children in the general population (GP children). We analyzed children with high-ris
Autor:
Vito Lampasona, Philipp Sifft, Markus Hippich, Jose Zapardiel-Gonzalo, Anette G. Ziegler, Merle M Böhmer, Ezio Bonifacio
Publikováno v:
Med (New York, N.y.)
Hippich et al update their surveillance of SARS-CoV-2 antibodies in the Bavarian childhood population and show an eight-fold prevalence increase during 2021 as compared to the end of first wave in 2020. Over 50% of positive children were asymptomatic
Autor:
the TEDDY Study Group, Anette-Gabriele Ziegler, Beena Akolkar, Desmond A. Schatz, Kendra Vehik, Jeffrey P. Krischer, William A. Hagopian, Jin-Xiong She, Åke Lernmark, Jorma Toppari, Marian J. Rewers, Markus Hippich, Christiane Winkler, Andreas Weiß, Ezio Bonifacio
Publikováno v:
Diabetes Care
Diabetes Care 44, 2260-2268 (2021)
Diabetes Care 44, 2260-2268 (2021)
OBJECTIVE Islet autoimmunity develops before clinical type 1 diabetes and includes multiple and single autoantibody phenotypes. The objective was to determine age-related risks of islet autoantibodies that reflect etiology and improve screening for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f9e2479c217ba73d8f0775896c85b9
https://doi.org/10.2337/figshare.13643756.v1
https://doi.org/10.2337/figshare.13643756.v1
Autor:
Leonard C. Harrison, Linda A. DiMeglio, Åke Lernmark, Carmella Evans-Molina, Markus Hippich, Anette-Gabriele Ziegler, Peter A. Gottlieb, John M. Wentworth, Stephen E. Gitelman, Connie S N Li-Wai-Suen, Naiara G. Bediaga, Peter G. Colman, Michael J. Haller, Diane K. Wherrett
Publikováno v:
Diabetologia, DOI: 10.1007/s00125-021-05523-2 (2021)
Diabetologia
Diabetologia
Aims/hypothesis Accurate prediction of disease progression in individuals with pre-symptomatic type 1 diabetes has potential to prevent ketoacidosis and accelerate development of disease-modifying therapies. Current tools for predicting risk require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13c0ba4936976e75eaca1419239ea9a
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62767
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62767
Autor:
Joseph F. Petrosino, Jan Knoop, Robin Assfalg, Ezio Bonifacio, Andreas Weiss, Peter Achenbach, Kristi L. Hoffman, Melanie Bunk, Anne Eugster, Jörg Hasford, Markus Pfirrmann, Anette-Gabriele Ziegler, Yannick F. Fuchs, Jose Zapardiel-Gonzalo, Anna Hofelich, Julia Reinhardt, Marc Weigelt, Claudia Matzke, Markus Hippich, Stefanie M. Hauck, Kathrin Halfter
BackgroundOral administration of antigen can induce immunological tolerance. Insulin is a key autoantigen in childhood type 1 diabetes with insulin autoimmunity often appearing in the first years of life. Here, oral insulin was given as antigen-speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee95dce39bd7668922f7eec2822fe580
https://doi.org/10.1101/2020.06.12.20129189
https://doi.org/10.1101/2020.06.12.20129189
Autor:
Ulrike Protzer, Peter Achenbach, Ezio Bonifacio, Susanne Heck, Merle Boehmer, Franziska Voss, Lisa Holthaus, Anette-Gabriele Ziegler, Martin Heigermoser, Tiziana C. Welzhofer, Joanna Stock, Dominik A. Ewald, F Haupt, Heidi Kapfelsperger, Lorenzo Piemonti, Benjamin A. Marcus, Markus Hippich, Annika Koelln, Jose Zapardiel-Gonzalo, Vito Lampasona, Kathrin de la Rosa, Robin Assfalg, Massimiliano Secchi
Publikováno v:
Med
Med (New York, N.y.)
Med (New York, N.y.)
Background Antibody responses to virus reflect exposure and potential protection. Methods We developed a highly specific and sensitive approach to measuring antibodies against SARS-CoV-2 for population-scale immune surveillance. Antibody positivity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c94b745fb5c471c6f139b74560f104
Autor:
Anette-Gabriele Ziegler, Otto Laub, Desiree Dunstheimer, Peter Achenbach, Martin Lang, Markus Hippich, F Haupt, Karin Lange, Christiane Winkler, Robin Assfalg, Kerstin Kick, Manja Jolink, Katharina Warncke, Ezio Bonifacio
Publikováno v:
JAMA
IMPORTANCE: Public health screening for type 1 diabetes in its presymptomatic stages may reduce disease severity and burden on a population level. OBJECTIVE: To determine the prevalence of presymptomatic type 1 diabetes in children participating in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e8f022cee77b1436ca644fffdc9c5d
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/76985
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/76985
Autor:
Christiane Winkler, Ricardo C. Ferreira, Anette-Gabriele Ziegler, Alexandra Oleynik, Thomas Briese, Komal Jain, Markus Hippich, Ezio Bonifacio
Publikováno v:
Acta Diabetologica. 55:881-884