Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Markus Heubes"'
A solid DMSO salvate of a compound of fornula (I) is described, which is a useful intemediate far preparing the broad spectrum antibiotics Ceftobiprole and Ceftobiprole Medocaril.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::06b18b99cbe2eb2f3a7d5a3a63fb4021
http://hdl.handle.net/11585/767799
http://hdl.handle.net/11585/767799
Autor:
Sabine Altermann, Thomas Gottwald, Georg Stapf, Jens Hartung, Christine Schur, Irina Kempter, Markus Heubes, Uwe Bergsträßer
Publikováno v:
Tetrahedron. 65:7527-7532
Experimentally determined barriers to O-acyl group topomerization in mixed anhydrides composed of β-disubstituted carboxylic acids and cyclic thiohydroxamic acid N-hydroxy-4-methylthiazole-2(3H)-thione were located in the range of ΔG‡320=68±8 kJ
Autor:
Gerhard Bringmann, Stefanie Diem, Markus Heubes, Markus Herderich, Jan Schlauer, Michael Wohlfarth, Wael Saeb, Heiko Rischer
Publikováno v:
Bringmann, G, Wohlfarth, M, Rischer, H, Heubes, M, Saeb, W, Diem, S, Herderich, M & Schlauer, J 2001, ' A photometric screening method for dimeric naphthylisoquinoline alkaloids and complete
structural eludication of a dimer in crude plant extracts, by the LC−MS/LC−NMR/LC−CD Triad ', Analytical Chemistry, vol. 73, no. 11, pp. 2571-2577 . https://doi.org/10.1021/ac001503q
structural eludication of a dimer in crude plant extracts, by the LC−MS/LC−NMR/LC−CD Triad ', Analytical Chemistry, vol. 73, no. 11, pp. 2571-2577 . https://doi.org/10.1021/ac001503q
An efficient evaluation procedure for the chemical screening and on-line structural elucidation of dimeric naphthylisoquinoline alkaloids has been developed. The method is based on the lead tetraacetate oxidation of the central binaphthalene core of
Autor:
Masaki Fujita, Motoharu Seiki, Markus Heubes, D. John Faulkner, Shigeki Matsunaga, Nobuhiro Fusetani, Yoichi Nakao, Yoshifumi Itoh, Rob W. M. Van Soest
Publikováno v:
Tetrahedron. 57:3885-3890
Two inhibitors of membrane-type matrix metalloproteinase (MT1-MMP) were isolated from a marine sponge Cribrochalina sp. Their structures were elucidated as unusual phosphorylated sterol sulfates by spectroscopic and chemical methods. One of the stero
Autor:
Lloyd M. Jackman, Rüdiger Bertermann, Peter Luger, Alan J. Benesi, Tibor Koritsanszky, Hans Förster, Andreas Mayer, Helmut Prof Dr Quast, Dieter Zobel, Markus Heubes, and Maximilian Seefelder
Publikováno v:
Journal of the American Chemical Society. 122:4455-4463
X-ray crystallographic structures of two polymorphs (α- and β-forms) of 1,5-dimethylsemibullvalene-2,6-dicarbonitrile, in which the molecules undergo rapid, nondegenerate Cope rearrangement, have been obtained over the temperature range 20−295 K.
Autor:
Markus Heubes, and Bernd Schöner, Michael Ochse, O. Schupp, Matthias Breuning, Lothar Göbel, Gerhard Bringmann
Publikováno v:
The Journal of Organic Chemistry. 65:722-728
Configurationally unstable biaryl lactones of type (M)-1 ⇌ (P)-1 and ring-opened 2-acyl-2‘-hydroxy biaryl compounds of type (M)-4 ⇌ (P)-4 are versatile precursors for the atroposelective preparation of axially chiral biaryls. The activation bar
Autor:
Eva‐Maria Peters, Svetlana Ivanova, Maximilian Seefelder, Markus Heubes, Helmut Quast, Karl Peters
Publikováno v:
European Journal of Organic Chemistry. 1999:3343-3351
Oxidation with barium manganate of the enol of tetraacetylethane (10) affords tetraacetylethylene (7a) in good yield. Treatment of the 1,3-diketones 15a and b with iodosobenzene in the presence of boron trifluoride does not result in oxidative coupli
Autor:
Maximilian Seefelder, Markus Heubes, Christian Becker, Helmut Quast, Karl Peters, Eva-Maria Peters
Publikováno v:
European Journal of Organic Chemistry. 1999:2763-2779
The deuterium-labelled 2,4,6,8-substituted barbaralanes [D5]-1a and b, and the two model barbaralanes 15 und 19 for the estimation of 13C chemical shifts in the slow-exchange limit are synthesised from bicyclo[3.3.1]nona-3,7-diene-2,6-dione (5). –
Publikováno v:
Canadian Journal of Chemistry. 77:1869-1886
The Brönsted-Lewis superacid HSO3F-SbF5 or "magic acid" is re-investigated by modern 19F NMR methods over a wide concentration range. The system is found to be considerably more complex than had been assumed previously. A total of 13 different anion
Publikováno v:
European Journal of Organic Chemistry. 1999:813-822
Whereas 1,5-dimethylsemibullvalene (1b) equilibrates with 1,5-dimethylcyclooctatetraene (2b), the semibullvalene-2,6-dicarbonitriles 13 rearrange irreversibly to afford mixtures of the isomeric cyclooctatetraene-1,5-dicarbonitriles 14 and 15. Arrheni