Gastric cancer detection based on cell‐free DNA in blood: A systematic review and meta‐analysis

Autor: Mona Wang, Xiaohan Fan, Boyang Huang, Kaifeng Pan, Markus Gerhard, Raquel Mejías‐Luque, Yang Zhang

Publikováno v: Clinical and Translational Discovery, Vol 4, Iss 4, Pp n/a-n/a (2024)

Abstract Objective Screening and early diagnosis of gastric cancer (GC) are crucial for improved prognosis. However, gastroscopic screening is not feasible in large populations due to its high cost and invasive nature. The detection of circulating ce

Externí odkaz: https://doaj.org/article/1d509c8ca41849c99ce2b326dee93e3d

Predicting the next pandemic: VACCELERATE ranking of the World Health Organization's Blueprint for Action to Prevent Epidemics

Autor: Jon Salmanton-García, Pauline Wipfler, Janina Leckler, Pontus Nauclér, Patrick W. Mallon, Patricia C.J.L. Bruijning-Verhagen, Heinz-Joseph Schmitt, Ullrich Bethe, Ole F. Olesen, Fiona A. Stewart, Kerstin Albus, Oliver A. Cornely, Martin Busch, Ulrike Seifert, Andreas Widmer, Miki Nagao, Jordi Rello, Tatina Todorova, Sabina Cviljević, Christopher H. Heath, Ligita Jančorienė, Thea Koelsen Fischer, Hans Martin Orth, Isik Somuncu Johansen, Mehmet Doymaz, Athanasios Tragiannidis, Thomas Löscher, Jin-Fu Xu, Petr Husa, José Antonio Oteo, Mohammad I. Issack, Markus Zeitlinger, Roger Le Grand, Przemysław Zdziarski, Fatih Demirkan, Paloma Merino Amador, Tomás García-Lozano, Qing Cao, Lourdes Vázquez, Juan Pablo Caeiro, Peter Hermans, Shahroch Nahrwar, Korkut Avsar, Deepak Kumar, Norma Fernández, Masoud Mardani, Esther Segal, Angelo Pan, Despoina Gkentzi, Georgia Gioula, Jorge Alberto Cortés, Joaquim Oliveira, Pierre van Damme, Mohd Zaki Bin Mohd Zaili, Spinello Antinori, Birutė Zablockienė, Georgios Papazisis, Chioma Inyang Aneke, Maricela Valerio, Samuel McConkey, Avinash Aujayeb, Anna Maria Azzini, Jelena Roganović, Kristin Greve-Isdahl Mohn, Peter Kremsner, Effrossyni Gkrania-Klotsas, Dora Corzo, Nina Khanna, Tomasz Smiatacz, Simone Scheithauer, Maria Merelli, Boris Klempa, Radovan Vrḫovac, Antonio Ruggiero, Pankaj Chaudhary, Julio Maquera-Afaray, Miquel Ekkelenkamp, Pavel Jindra, Nikola Pantić, Gemma Jiménez Guerra, Guenter Weiss, Behrad Roohi, Christos D. Argyropoulos, Sven Aprne Silfverdal, Jens van Praet, Zumrut Sahbudak Bal, Souha Kanj, Barnaby Young, Zoi Dorothea Pana, Emmanuel Roilides, Stephen C. Stearns, Joost Wauters, Jesús Rodríguez Baño, Mathias W. Pletz, Maja Travar, Steven Kühn, Fernando Riera, Daniel Cornely, Vlad Jeni Laura, Philipp Koehler, Brian Eley, Pravin K. Nair, Sandra Ciesek, Ioana Diana Olaru, Laura Marques, Emanuele Pontali, Alexandra Naunheim, Adrian Lieb, Markus Gerhard, Joveria Qais Farooqi, Lance Turtle, Gustavo Adolfo Méndez, Rebecca Jane Cox, Nigel Goodman, Billie Caceca, Javier Pemán, Halima Dawood, Helena Hervius Askling, Anders Fomsgaard, Alejandra Calderón Hernández, Cornelia Staehelin, Chia-Ying Liu, Giancarlo Icardi, Elio Castagnola, Helmut J.F. Salzer, Jens Lundgren, Samir Javadli, Fabio Forghieri

Publikováno v: Travel Medicine and Infectious Disease, Vol 57, Iss , Pp 102676- (2024)

Introduction: The World Health Organization (WHO)'s Research and Development (R&D) Blueprint for Action to Prevent Epidemics, a plan of action, highlighted several infectious diseases as crucial targets for prevention. These infections were selected

Externí odkaz: https://doaj.org/article/ef09014bf9ba45e6b6461ba190f3d42b

Metabolite Alterations and Interactions with Microbiota in Helicobacter pylori-Associated Gastric Lesions

Autor: Lei Peng, Yang Guo, Markus Gerhard, Juan-Juan Gao, Zong-Chao Liu, Raquel Mejías-Luque, Lian Zhang, Michael Vieth, Jun-Ling Ma, Wei-Dong Liu, Zhe-Xuan Li, Tong Zhou, Wen-Qing Li, Wei-Cheng You, Yang Zhang, Kai-Feng Pan

Publikováno v: Microbiology Spectrum, Vol 11, Iss 4 (2023)

ABSTRACT Metabolites and their interactions with microbiota may be involved in Helicobacter pylori-associated gastric lesion development. This study aimed to explore metabolite alterations upon H. pylori eradication and possible roles of microbiota-m

Externí odkaz: https://doaj.org/article/8bd89e4f513045e78eee2d82d437d3e4

Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents

Autor: Nina Koerber, Alina Priller, Sarah Yazici, Tanja Bauer, Cho-Chin Cheng, Hrvoje Mijočević, Hannah Wintersteller, Samuel Jeske, Emanuel Vogel, Martin Feuerherd, Kathrin Tinnefeld, Christof Winter, Jürgen Ruland, Markus Gerhard, Bernhard Haller, Catharina Christa, Otto Zelger, Hedwig Roggendorf, Martin Halle, Johanna Erber, Paul Lingor, Oliver Keppler, Dietmar Zehn, Ulrike Protzer, Percy A. Knolle

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Waning immunity to SARS-CoV-2 is of concern. Here the authors follow spike- and nucleocapsid specific immunity in convalescent individuals for 9 months observing a decline in antibody levels but persisting T cell response. Vaccination approximately 1

Externí odkaz: https://doaj.org/article/bbeaccaf4069413988e20f5fcbf34dd9

RBD-Based ELISA and Luminex Predict Anti-SARS-CoV-2 Surrogate-Neutralizing Activity in Two Longitudinal Cohorts of German and Spanish Health Care Workers

Autor: Ruth Aguilar, Xue Li, Claudia S. Crowell, Teresa Burrell, Marta Vidal, Rocio Rubio, Alfons Jiménez, Pablo Hernández-Luis, Dieter Hofmann, Hrvoje Mijočević, Samuel Jeske, Catharina Christa, Elvira D'Ippolito, Paul Lingor, Percy A. Knolle, Hedwig Roggendorf, Alina Priller, Sarah Yazici, Carlo Carolis, Alfredo Mayor, Patrik Schreiner, Holger Poppert, Henriette Beyer, Sophia E. Schambeck, Luis Izquierdo, Marta Tortajada, Ana Angulo, Erwin Soutschek, Pablo Engel, Alberto Garcia-Basteiro, Dirk H. Busch, Gemma Moncunill, Ulrike Protzer, Carlota Dobaño, Markus Gerhard

Publikováno v: Microbiology Spectrum, Vol 11, Iss 1 (2023)

ABSTRACT The ability of antibodies to neutralize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important correlate of protection. For routine evaluation of protection, however, a simple and cost-efficient anti-SARS-CoV-2 serologi

Externí odkaz: https://doaj.org/article/a6e424f665b94f03bce0933c83ef8b75