Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Markus G. Mohaupt"'
Autor:
Benedikt Gasser, Genevieve Escher, Anca-Elena Calin, Michael Deppeler, Miriam Marchon, Hiten D. Mistry, Johann Kurz, Markus G. Mohaupt
Publikováno v:
Life, Vol 13, Iss 5, p 1094 (2023)
Background: We recently reported that metformin administration has substantial effects on steroid hormone concentrations. In this study, we specifically explored which enzymatic activities were affected before a first treatment versus after a time of
Externí odkaz:
https://doaj.org/article/ea6fc1b42df846899d05c80da21375f6
Autor:
Rahel Klossner, Michael Groessl, Nadine Schumacher, Michaela Fux, Geneviève Escher, Sophia Verouti, Heidi Jamin, Bruno Vogt, Markus G. Mohaupt, Carine Gennari-Moser
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The steroid hormone progesterone accounts for immune tolerance in pregnancy. Enhanced progesterone metabolism to 6α-OH-pregnanolone occurs in complicated pregnancies such as in preeclampsia with preterm delivery or intrauterine growth restr
Externí odkaz:
https://doaj.org/article/75cad88b199f45d5bab5f61446be107f
Publikováno v:
Life, Vol 12, Iss 7, p 1004 (2022)
Background: Evidence exists that steroid hormones are altered in individuals with autism, especially androgens. Despite lower prevalence in girls than boys, evidence of potential alterations in progesterone metabolites is sparse, so the aim of this s
Externí odkaz:
https://doaj.org/article/16cd5b959ec64b77bd18316ef53844e3
Autor:
Sofia Christakoudi, Manohursingh Runglall, Paula Mobillo, Irene Rebollo-Mesa, Tjir-Li Tsui, Estefania Nova-Lamperti, Catharine Taube, Sonia Norris, Yogesh Kamra, Rachel Hilton, Titus Augustine, Sunil Bhandari, Richard Baker, David Berglund, Sue Carr, David Game, Sian Griffin, Philip A. Kalra, Robert Lewis, Patrick B. Mark, Stephen D. Marks, Iain MacPhee, William McKane, Markus G. Mohaupt, Estela Paz-Artal, Sui Phin Kon, Daniel Serón, Manish D. Sinha, Beatriz Tucker, Ondrej Viklický, Daniel Stahl, Robert I. Lechler, Graham M. Lord, Maria P. Hernandez-Fuentes
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102899- (2020)
Background: Kidney transplant recipients (KTRs) with “operational tolerance” (OT) maintain a functioning graft without immunosuppressive (IS) drugs, thus avoiding treatment complications. Nevertheless, IS drugs can influence gene-expression signa
Externí odkaz:
https://doaj.org/article/3e888ca856124c02877325b343eab615
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12324 (2021)
Introduction: There is increasing evidence that steroid hormone levels and, especially, androgen levels are elevated in autism. An overactivity of 17, 20-lyase with a higher production of the testosterone precursors dehydroepiandrosterone (DHEA) and
Externí odkaz:
https://doaj.org/article/bad54115726d40908c124cd0bfd85872
Autor:
Hiten D. Mistry, Lesia O. Kurlak, Yosef T. Mansour, Line Zurkinden, Markus G. Mohaupt, Geneviève Escher
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1186-1195 (2017)
Preeclampsia is a pregnancy-specific condition that leads to increased cardiovascular risk in later life. A decrease in cholesterol efflux capacity is linked to CVD. We hypothesized that in preeclampsia there would be a disruption of maternal/fetal p
Externí odkaz:
https://doaj.org/article/d8f7e66350144491ab19250f45cf463b
Autor:
Nicole Eisele, Rahel Klossner, Geneviève Escher, Stefan Rudloff, Alexey Larionov, Franziska Theilig, Markus G. Mohaupt, Hiten D. Mistry, Carine Gennari‐Moser
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 15 (2018)
Background In pregnancy, a high plasma volume maintains uteroplacental perfusion and prevents placental ischemia, a condition linked to elevated maternal blood pressure (BP). Reducing BP by increasing Na+ intake via plasma volume expansion appears co
Externí odkaz:
https://doaj.org/article/0a1a22135d7d4371a3d742c988f83422
Autor:
Hiten D. Mistry, Rahel Klossner, Sampada Kallol, Michael P. Lüthi, Ruedi Moser, Henning Schneider, Edgar C. Ontsouka, Lesia O. Kurlak, Markus G. Mohaupt, Christiane Albrecht
Publikováno v:
Mistry, Hiten D; Klossner, Rahel; Kallol, Sampada; Lüthi, Michael P; Moser, Ruedi; Schneider, Henning; Ontsouka, Edgar C; Kurlak, Lesia O; Mohaupt, Markus G.; Albrecht, Christiane (2022). Effects of aldosterone on the human placenta: Insights from placental perfusion studies. Placenta, 123, pp. 32-40. Elsevier 10.1016/j.placenta.2022.03.129
INTRODUCTION In pregnancy, aldosterone is linked to maternal plasma volume expansion, improved fetal and placental growth/angiogenesis and reduced maternal blood pressure. Aldosterone levels are low in women with pre-eclampsia. Given the placental gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb1e9b71e0899da568ac28482cb6066
https://boris.unibe.ch/169908/1/1-s2.0-S0143400422002156-main.pdf
https://boris.unibe.ch/169908/1/1-s2.0-S0143400422002156-main.pdf
Publikováno v:
Gasser, Benedikt Andreas; Kurz, Johann; Senn, Walter; Escher, Genevieve; Mohaupt, Markus Georg (2021). Stress-induced alterations of social behavior are reversible by antagonism of steroid hormones in C57/BL6 mice. Naunyn-Schmiedeberg's archives of pharmacology, 394(1), pp. 127-135. Springer 10.1007/s00210-020-01970-7
Naunyn-Schmiedeberg's Archives of Pharmacology
Naunyn-Schmiedeberg's Archives of Pharmacology
Various disturbances of social behavior, such as autism, depression, or posttraumatic stress disorder, have been associated with an altered steroid hormone homeostasis and a dysregulation of the hypothalamus–pituitary–adrenal axis. A link between
Autor:
Daniel Ackermann, Bruno Vogt, Murielle Bochud, Michel Burnier, Pierre-Yves Martin, Fred Paccaud, Georg Ehret, Idris Guessous, Belen Ponte, Menno Pruijm, Antoinette Pechère-Bertschi, Heidi Jamin, Rahel Klossner, Bernhard Dick, Markus G. Mohaupt, Carine Gennari-Moser
Publikováno v:
Ackermann, Daniel; Vogt, Bruno; Bochud, Murielle; Burnier, Michel; Martin, Pierre-Yves; Paccaud, Fred; Ehret, Georg; Guessous, Idris; Ponte, Belen; Pruijm, Menno; Pechère-Bertschi, Antoinette; Jamin, Heidi; Klossner, Rahel; Dick, Bernhard; Mohaupt, Markus G; Gennari-Moser, Carine (2022). Increased glucocorticoid metabolism in diabetic kidney disease. PLoS ONE, 17(6), e0269920. Public Library of Science 10.1371/journal.pone.0269920
PloS one, vol. 17, no. 6, pp. e0269920
PloS one, vol. 17, no. 6, pp. e0269920
Aims Glomerular damage indicated by proteinuria is a main symptom in diabetic nephropathy. Mineralocorticoid receptor (MR) antagonists (MRAs) are beneficial irrespective of aldosterone availability. Thus, we hypothesized an alternatively activated MR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c20df7ca4871c23bff8a1569a57f2a2
https://boris.unibe.ch/170890/1/journal.pone.0269920.pdf
https://boris.unibe.ch/170890/1/journal.pone.0269920.pdf