Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Markus Furter"'
1
Akademický článek
Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection.
Autor: Ersin Gül, Ursina Enz, Luca Maurer, Andrew Abi Younes, Stefan A Fattinger, Bidong D Nguyen, Annika Hausmann, Markus Furter, Manja Barthel, Mikael E Sellin, Wolf-Dietrich Hardt
Publikováno v: PLoS Pathogens, Vol 19, Iss 6, p e1011235 (2023)
Recruitment of neutrophils into and across the gut mucosa is a cardinal feature of intestinal inflammation in response to enteric infections. Previous work using the model pathogen Salmonella enterica serovar Typhimurium (S.Tm) established that invas
Externí odkaz: https://doaj.org/article/eba57bd740684b71a7c87e04baa65b1d
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2
Akademický článek
miR-802 regulates Paneth cell function and enterocyte differentiation in the mouse small intestine
Autor: Algera Goga, Büsra Yagabasan, Karolin Herrmanns, Svenja Godbersen, Pamuditha N. Silva, Remy Denzler, Mirjam Zünd, Markus Furter, Gerald Schwank, Shinichi Sunagawa, Wolf-Dietrich Hardt, Markus Stoffel
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Homeostasis of the intestinal epithelium is crucial for the maintenance of the epithelial barrier. Here, the authors show that mir-802 ablation in the mouse intestine impairs enterocyte differentiation and glucose absorption, enhances Paneth cell fun
Externí odkaz: https://doaj.org/article/c7f78656546746ebbee47397d3bee506
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3
Akademický článek
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epithelium.
Autor: Stefan A Fattinger, Desirée Böck, Maria Letizia Di Martino, Sabrina Deuring, Pilar Samperio Ventayol, Viktor Ek, Markus Furter, Saskia Kreibich, Francesco Bosia, Anna A Müller-Hauser, Bidong D Nguyen, Manfred Rohde, Martin Pilhofer, Wolf-Dietrich Hardt, Mikael E Sellin
Publikováno v: PLoS Pathogens, Vol 16, Iss 5, p e1008503 (2020)
Salmonella enterica serovar Typhimurium (S.Tm) infections of cultured cell lines have given rise to the ruffle model for epithelial cell invasion. According to this model, the Type-Three-Secretion-System-1 (TTSS-1) effectors SopB, SopE and SopE2 driv
Externí odkaz: https://doaj.org/article/5a9d7e06a10540bb8d6ba0e1370f2e5b
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4
Akademický článek
Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract
Autor: Markus Furter, Mikael E. Sellin, Gunnar C. Hansson, Wolf-Dietrich Hardt
Publikováno v: Cell Reports, Vol 27, Iss 9, Pp 2665-2678.e3 (2019)
Summary: Mucus separates gut-luminal microbes from the tissue. It is unclear how pathogens like Salmonella Typhimurium (S.Tm) can overcome this obstacle. Using live microscopy, we monitored S.Tm interactions with native murine gut explants and studie
Externí odkaz: https://doaj.org/article/af915271baa148419b5b661abac1c64f
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5
Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells duringSalmonellagut infection
Autor: Ersin Gül, Stefan A. Fattinger, Bidong D. Nguyen, Annika Hausmann, Markus Furter, Manja Barthel, Mikael E. Sellin, Wolf-Dietrich Hardt
SummaryRecruitment of neutrophils into the gut epithelium is a cardinal feature of intestinal inflammation in response to enteric infections. Previous work using the model pathogenSalmonellaTyphimurium (S. Tm) established that invasion of intestinal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54680d53e9bbf3e8ab3d8b965bbd7c4d
https://doi.org/10.1101/2023.02.23.529832
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6
Gasdermin D is the only Gasdermin that provides non-redundant protection against acuteSalmonellagut infection
Autor: Stefan A. Fattinger, Luca Maurer, Petra Geiser, Ursina Enz, Suwannee Ganguillet, Ersin Gül, Sanne Kroon, Benjamin Demarco, Markus Furter, Manja Barthel, Pawel Pelczar, Feng Shao, Petr Broz, Mikael E. Sellin, Wolf-Dietrich Hardt
Gasdermins (GSDMs) share a common functional domain structure and are best known for their capacity to form membrane pores. These pores are hallmarks of a specific form of cell death called pyroptosis and mediate the secretion of pro-inflammatory cyt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afdeb608f0d0a519230fc61f6bd4a9a4
https://doi.org/10.1101/2022.11.24.517575
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8
Epithelium-autonomous NAIP/NLRC4 prevents TNF-driven inflammatory destruction of the gut epithelial barrier in Salmonella-infected mice
Autor: Stefan A, Fattinger, Petra, Geiser, Pilar, Samperio Ventayol, Maria Letizia, Di Martino, Markus, Furter, Boas, Felmy, Erik, Bakkeren, Annika, Hausmann, Manja, Barthel-Scherrer, Ersin, Gül, Wolf-Dietrich, Hardt, Mikael E, Sellin
Publikováno v: Mucosal Immunology
The gut epithelium is a critical protective barrier. Its NAIP/NLRC4 inflammasome senses infection by Gram-negative bacteria, including Salmonella Typhimurium (S.Tm) and promotes expulsion of infected enterocytes. During the first ~12–24 h, this red
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4eaea0a8254d9920787e0cd489681f52
https://pubmed.ncbi.nlm.nih.gov/33731826
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