Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Markus Fridén"'
Autor:
Magnus Schou, Pär Ewing, Zsolt Cselenyi, Markus Fridén, Akihiro Takano, Christer Halldin, Lars Farde
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Background Positron emission tomography (PET) is a non-invasive molecular imaging technique that traces the distribution of radiolabeled molecules in experimental animals and human subjects. We hypothesized that PET could be used to visualiz
Externí odkaz:
https://doaj.org/article/b5670c54e71a4432942d0c3a22be322f
Autor:
Erica Bäckström, Gregory Hamm, Anna Nilsson, Britt-Marie Fihn, Nicole Strittmatter, Per Andrén, Richard J. A. Goodwin, Markus Fridén
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 838-845 (2018)
Treatment of respiratory disease with a drug delivered via inhalation is generally held as being beneficial as it provides direct access to the lung target site with a minimum systemic exposure. There is however only limited information of the region
Externí odkaz:
https://doaj.org/article/4e04b7a12c8d4b68bb241d9c1f1a4877
Autor:
Stina, Syvänen, Markus, Fridén
Publikováno v:
Pharmaceutical Research. 39:1291-1296
Autor:
Irena Loryan, Andreas Reichel, Bo Feng, Christoffer Bundgaard, Christopher Shaffer, Cory Kalvass, Dallas Bednarczyk, Denise Morrison, Dominique Lesuisse, Edmund Hoppe, Georg C. Terstappen, Holger Fischer, Li Di, Nicola Colclough, Scott Summerfield, Stephen T. Buckley, Tristan S. Maurer, Markus Fridén
Publikováno v:
Pharmaceutical Research. 39:1321-1341
Purpose More than 15 years have passed since the first description of the unbound brain-to-plasma partition coefficient (Kp,uu,brain) by Prof. Margareta Hammarlund-Udenaes, which was enabled by advancements in experimental methodologies including cer
Autor:
Maria Lindh, Alexander Persson, William Lövfors, Christian Simonsson, Erica Bäckström, Markus Fridén, Elin Nyman, Gunnar Cedersund, Daniel Eklund
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Both initiation and suppression of inflammation are hallmarks of the immune response. If not balanced, the inflammation may cause extensive tissue damage, which is associated with common diseases, e.g., asthma and atherosclerosis. Anti-inflammatory d
Autor:
Gregory Hamm, Richard J. A. Goodwin, Nicole Strittmatter, Markus Fridén, Mikael Brülls, Anna Nilsson, Erica Bäckström, Per E. Andrén, Ken Grime
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 33:43-53
Background: For the treatment of respiratory disease, inhaled drug delivery aims to provide direct access to pharmacological target sites while minimizing systemic exposure. Despite this long-held tenet of inhaled therapeutic advantage, there are lim
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3425-3433
This study aimed at evaluating how encapsulation in a regular nanocarrier (NC) (providing extended circulation time) or in a brain-targeting NC (providing prolonged circulation time and increased brain uptake) may influence the therapeutic index comp
Autor:
Jens M. Hohlfeld, Meike Müller, Cornelia Faulenbach, Philipp Badorrek, Olaf Holz, Markus Fridén, Birthe D. Ellinghusen, Stina Stomilovic, Ulf Eriksson, Anders Lundqvist, Muhammad Waqas Sadiq
Publikováno v:
British journal of pharmacologyREFERENCES. 178(22)
Background and purpose Human pharmacokinetic studies of lung-targeted drugs are typically limited to measurements of systemic plasma concentrations, which provide no direct information on lung target-site concentrations. We aimed to evaluate lung pha
Autor:
Markus Fridén, Elin Boger
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 32:1-12
Predicting local lung tissue pharmacodynamic (PD) responses of inhaled drugs is a longstanding challenge related to the lack of experimental techniques to determine local free drug concentrations. This has prompted the use of physiologically based ph
Autor:
Elham Amini, Per Bäckman, Erica Bäckström, Martyn Biddiscombe, Britta Bonn, Jens Markus Borghardt, Joy Conway, Anne Haaije de Boer, Martin Donnelley, Zachary Enlo-Scott, Ben Forbes, Markus Fridén, Mark Gardner, Anthony J. Hickey, Anneke Himstedt, Guenther Hochhaus, Eric A. Hoffman, Stavros Kassinos, Pantelis Koullapis, Ching-Long Lin, Hans Lundbäck, Kaye Morgan, Bo Olsson, David Parsons, Matthew Perry, Fotos Stylianou, Mårten Svensson, Magda Swedrowska, Josué Sznitman, Kyrre Thalberg, Omar Usmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f38ff3881f729112d0edfae6949002
https://doi.org/10.1016/b978-0-12-814974-4.00023-7
https://doi.org/10.1016/b978-0-12-814974-4.00023-7