Zobrazeno 1 - 10
of 1 364
pro vyhledávání: '"Markus F, Neurath"'
Autor:
Kim Wagner, Tanja M. Müller, Francesco Vitali, Sarah Fischer, Sophie Haberkamp, Rachel Rouse-Merkel, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: There is an increasing diversification in the treatment landscape for inflammatory bowel diseases (IBD) leading to therapeutic challenges that can only incompletely be covered by prospective randomized double-blind trials. Real-world obse
Externí odkaz:
https://doaj.org/article/0b42c0608bb84cbaa9ca90207dee411f
Autor:
Kenji Suzuki, Yukinori Sameshima, Junji Yokoyama, Shuji Terai, Hiroyuki Yoneyama, Raja Atreya, Markus F. Neurath, Toshifumi Hibi, Hitoshi Asakura
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-10 (2024)
Abstract Background Carbohydrate sulfotransferase 15 (CHST15) is an enzyme biosynthesizing matrix glycosaminoglycan that modulates tissue remodeling. We evaluated the efficacy of add-on submucosal injections of GUT-1, the RNA oligonucleotide inhibito
Externí odkaz:
https://doaj.org/article/4d12c4d2ddc145778e89ea6704cc7480
Autor:
Maximilian Wiendl, Mark Dedden, Li-Juan Liu, Anna Schweda, Eva-Maria Paap, Karen A.-M. Ullrich, Leonie Hartmann, Luisa Wieser, Francesco Vitali, Imke Atreya, Tanja M. Müller, Claudia Günther, Raja Atreya, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Despite promising preclinical and earlier clinical data, a recent phase III trial on the anti-β7 integrin antibody etrolizumab in Crohn’s disease (CD) did not reach its primary endpoint. The mechanisms leading to this outcome are not well
Externí odkaz:
https://doaj.org/article/acac8322e2ba43b1966b2f33b0b17d77
Autor:
Imke Atreya, Markus F. Neurath
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/9b7a4414c12c48a99578d0cab4cdf16d
Autor:
Anna P. Träger, Josefine S. Günther, Roman Raming, Lars-Philip Paulus, Werner Lang, Alexander Meyer, Julius Kempf, Milenko Caranovic, Yi Li, Alexandra L. Wagner, Lina Tan, Vera Danko, Regina Trollmann, Joachim Woelfle, Daniel Klett, Markus F. Neurath, Adrian P. Regensburger, Markus Eckstein, Wolfgang Uter, Michael Uder, Yvonne Herrmann, Maximilian J. Waldner, Ferdinand Knieling, Ulrich Rother
Publikováno v:
Photoacoustics, Vol 35, Iss , Pp 100579- (2024)
Peripheral arterial disease (PAD) leads to chronic vascular occlusion and results in end organ damage in critically perfused limbs. There are currently no clinical methods available to determine the muscular damage induced by chronic mal-perfusion. T
Externí odkaz:
https://doaj.org/article/fb510c5fc8a546ee9909ffe916d51dd3
Autor:
Adrian P. Regensburger, Markus Eckstein, Matthias Wetzl, Roman Raming, Lars-Philip Paulus, Adrian Buehler, Emmanuel Nedoschill, Vera Danko, Jörg Jüngert, Alexandra L. Wagner, Alexander Schnell, Aline Rückel, Ulrich Rother, Oliver Rompel, Michael Uder, Arndt Hartmann, Markus F. Neurath, Joachim Woelfle, Maximilian J. Waldner, André Hoerning, Ferdinand Knieling
Publikováno v:
Photoacoustics, Vol 35, Iss , Pp 100578- (2024)
Multispectral optoacoustic tomography (MSOT) allows non-invasive molecular disease activity assessment in adults with inflammatory bowel disease (IBD). In this prospective pilot-study, we investigated, whether increased levels of MSOT haemoglobin par
Externí odkaz:
https://doaj.org/article/8aac55cc9b8d47b8968e97f185cb219a
Autor:
Katrin Sommer, Hilal Garibagaoglu, Eva-Maria Paap, Maximilian Wiendl, Tanja M. Müller, Imke Atreya, Gerhard Krönke, Markus F. Neurath, Sebastian Zundler
Publikováno v:
Cells, Vol 13, Iss 10, p 819 (2024)
Monocytes, as well as downstream macrophages and dendritic cells, are essential players in the immune system, fulfilling key roles in homeostasis as well as in inflammatory conditions. Conventionally, driven by studies on reporter models, mouse monoc
Externí odkaz:
https://doaj.org/article/2bf2d7289b8c4c54b8f81461aac155f8
Autor:
Francesco Vitali, Timo Rath, Entcho Klenske, Anna-Lena Vögele, Ingo Ganzleben, Sebastian Zundler, Deike Strobel, Carol Geppert, Arndt Hartmann, Markus F. Neurath, Raja Atreya
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: Effective management of patients with acute severe ulcerative colitis (ASUC) is a major challenge and there remains a paucity of available maintenance treatment options after efficacious cyclosporin induction therapy. Objectives: We inves
Externí odkaz:
https://doaj.org/article/6893d39668f04c80b05d2913832cad4b
Autor:
Markus F. Neurath
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 4, Pp 660-661 (2024)
Externí odkaz:
https://doaj.org/article/4455271c99ac4454bf7b34ba0fd4f5e7
Autor:
Timo Rath, Raja Atreya, Julia Bodenschatz, Wolfgang Uter, Carol I. Geppert, Francesco Vitali, Sebastian Zundler, Maximilian J. Waldner, Arndt Hartmann, Markus F. Neurath
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundAchieving endoscopic remission is a key therapeutic goal in patients with ulcerative colitis (UC) that is associated with favorable long-term disease outcomes. Here, we prospectively compared the predictive value of endoscopic and/or histol
Externí odkaz:
https://doaj.org/article/4cd845a12a4f48249a51e409c3b313da