Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Markus Englert"'
Autor:
Nikita E Chavarria, Sungmin Hwang, Shiyun Cao, Xian Fu, Mary Holman, Dina Elbanna, Suzanne Rodriguez, Deanna Arrington, Markus Englert, Sivakumar Uthandi, Dieter Söll, Julie A Maupin-Furlow
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99104 (2014)
While cytoplasmic tRNA 2-thiolation protein 1 (Tuc1/Ncs6) and ubiquitin-related modifier-1 (Urm1) are important in the 2-thiolation of 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U) at wobble uridines of tRNAs in eukaryotes, the biocatalytic roles a
Externí odkaz:
https://doaj.org/article/879f6e3d13794a7a9af59d99112acedc
Autor:
Takuya Umehara, Markus Englert, Yane-Shih Wang, Dieter Söll, Noah M. Reynolds, Oscar Vargas-Rodriguez
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1861:3009-3015
Development of new aminoacyl-tRNA synthetase (aaRS)•tRNA pairs is central for incorporation of novel non-canonical amino acids (ncAAs) into proteins via genetic code expansion (GCE). The Escherichia coli and Caulobacter crescentus histidyl-tRNA syn
Autor:
Nikita E. Chavarria, Julie A. Maupin-Furlow, Xian Fu, Sivakumar Uthandi, Markus Englert, Dan Su, Shiyun Cao, Douglas J. Kojetin, Dieter Sӧll, Nathaniel L. Hepowit, Ian Mitchelle S. de Vera, Yifei Wu
Publikováno v:
The FEBS Journal. 283:3567-3586
Here we provide the first detailed biochemical study of a noncanonical E1-like enzyme with broad specificity for cognate ubiquitin-like (Ubl) proteins that mediates Ubl protein modification and sulfur mobilization to form molybdopterin and thiolated
Autor:
Nikos C. Kyrpides, Markus Englert, H. James Tripp, Edward M. Rubin, Corwin Miller, Takahito Mukai, Dieter Söll, Natalia Ivanova
Publikováno v:
Angewandte Chemie. 128:5423-5427
Selenocystein (Sec oder U) wird durch Neuzuordnung des Stopp-Codons UGA durch einen Sec-spezifischen Elongationsfaktor und eine charakteristische RNA-Struktur codiert. Um mogliche Codonvariationen zu finden, analysierten wir 6.4 Billionen Basenpaare
Autor:
Hai Xiong, Markus Englert, Dieter Söll, Chenguang Fan, Noah M. Reynolds, Scott J. Miller, Denton Hoyer
Publikováno v:
Angewandte Chemie International Edition. 55:4083-4086
Acetylation of lysine residues is an important post-translational protein modification. Lysine acetylation in histones and its crosstalk with other post-translational modifications in histone and non-histone proteins are crucial to DNA replication, D
Autor:
Markus Englert, Hai Xiong, Chenguang Fan, Scott J. Miller, Dieter Söll, Denton Hoyer, Noah M. Reynolds
Publikováno v:
Angewandte Chemie. 128:4151-4154
Publikováno v:
Nucleic Acids Research
Genetically encoded non-canonical amino acids are powerful tools of protein research and engineering; in particular they allow substitution of individual chemical groups or atoms in a protein of interest. One such amino acid is the tryptophan (Trp) a
Publikováno v:
RNA biology. 15(4-5)
In many organisms, the UGA stop codon is recoded to insert selenocysteine (Sec) into proteins. Sec incorporation in bacteria is directed by an mRNA element, known as the Sec-insertion sequence (SECIS), located downstream of the Sec codon. Unlike othe
Publikováno v:
Nucleic Acids Research
Selenocysteine (Sec) is naturally co-translationally incorporated into proteins by recoding the UGA opal codon with a specialized elongation factor (SelB in bacteria) and an RNA structural signal (SECIS element). We have recently developed a SECIS-fr
Autor:
Natalia Ivanova, Dieter Söll, Takahito Mukai, Nikos C. Kyrpides, Markus Englert, H. James Tripp, Edward M. Rubin, Oscar Vargas-Rodriguez
Publikováno v:
Nucleic Acids Research
Mukai, T; Vargas-Rodriguez, O; Englert, M; Tripp, HJ; Ivanova, NN; Rubin, EM; et al.(2017). Transfer RNAs with novel cloverleaf structures. Nucleic Acids Research, 45(5), 2776-2785. doi: 10.1093/nar/gkw898. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/5mm9v4zg
Nucleic acids research, vol 45, iss 5
Mukai, T; Vargas-Rodriguez, O; Englert, M; Tripp, HJ; Ivanova, NN; Rubin, EM; et al.(2017). Transfer RNAs with novel cloverleaf structures. Nucleic Acids Research, 45(5), 2776-2785. doi: 10.1093/nar/gkw898. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/5mm9v4zg
Nucleic acids research, vol 45, iss 5
© The Author(s) 2016. We report the identification of novel tRNA species with 12-base pair amino-acid acceptor branches composed of longer acceptor stem and shorter Tstem. While canonical tRNAs have a 7/5 configuration of the branch, the novel tRNAs