Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Markus C Kowarik"'
Autor:
Gisela Gabernet, Susanna Marquez, Robert Bjornson, Alexander Peltzer, Hailong Meng, Edel Aron, Noah Y Lee, Cole G Jensen, David Ladd, Mark Polster, Friederike Hanssen, Simon Heumos, nf-core community, Gur Yaari, Markus C Kowarik, Sven Nahnsen, Steven H Kleinstein
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 7, p e1012265 (2024)
Adaptive Immune Receptor Repertoire sequencing (AIRR-seq) is a valuable experimental tool to study the immune state in health and following immune challenges such as infectious diseases, (auto)immune diseases, and cancer. Several tools have been deve
Externí odkaz:
https://doaj.org/article/5c0227389c5848f6b0944bb48c78309a
Autor:
Alexander Hapfelmeier, Begum Irmak On, Mark Mühlau, Jan S. Kirschke, Achim Berthele, Christiane Gasperi, Ulrich Mansmann, Alexander Wuschek, Matthias Bussas, Martin Boeker, Antonios Bayas, Makbule Senel, Joachim Havla, Markus C. Kowarik, Klaus Kuhn, Ingrid Gatz, Helmut Spengler, Benedikt Wiestler, Lioba Grundl, Dominik Sepp, Bernhard Hemmer
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory disease affecting about 2.8 million people worldwide. Disease course after the most common diagnoses of relapsing-remitting multiple sclerosis (RRMS) and clinically isolated syndrome
Externí odkaz:
https://doaj.org/article/ea30989b6c7f42669dc1741927f2dd1f
Autor:
Constanze L. Kemmerer, Jens Schittenhelm, Evelyn Dubois, Laura Neumann, Lisa M. Häsler, Marius Lambert, Mirjam Renovanz, Stephan A. Kaeser, Ghazaleh Tabatabai, Ulf Ziemann, Ulrike Naumann, Markus C. Kowarik
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Diffuse gliomas are the most common malignant tumors of the central nervous system with poor treatment efficacy. Infiltration of immune cells into tumors during immunosurveillance is observed in multiple tumor entities and often a
Externí odkaz:
https://doaj.org/article/4ee9abee193d46629f282ebc347f2667
Autor:
Annerose Mengel, Lilyana Nenova, Karin A. L. Müller, Sven Poli, Markus C. Kowarik, Katharina Feil, Lars Mizera, Tobias Geisler, Jens Kübler, Heiko Mahrholdt, Ulrike Ernemann, Florian Hennersdorf, Ulf Ziemann, Konstantin Nikolaou, Meinrad Gawaz, Patrick Krumm, Simon Greulich
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
AimsIncreased high-sensitive cardiac troponin I (hs-cTnI) levels are common in patients with acute ischemic stroke. However, only a minority demonstrates culprit lesions on coronary angiography, suggesting other mechanisms, e.g., inflammation, as und
Externí odkaz:
https://doaj.org/article/f55416f947fd43649fca79e867881432
Autor:
Gildas Lepennetier, Zsuzsanna Hracsko, Marina Unger, Martijn Van Griensven, Verena Grummel, Markus Krumbholz, Achim Berthele, Bernhard Hemmer, Markus C. Kowarik
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-11 (2019)
Abstract Background Cytokines play multiple roles during neuro-inflammatory processes and several cytokines have been studied in the context of specific diseases. This study provides a comprehensive picture of cerebrospinal fluid (CSF) changes during
Externí odkaz:
https://doaj.org/article/12b25f15e501401e8afe3eb49b4bc2cc
Autor:
Christoph Kessler, Christoph Ruschil, Ahmed Abdelhak, Carlo Wilke, Aleksandra Maleska, Jens Kuhle, Markus Krumbholz, Markus C. Kowarik, Rebecca Schüle
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13466 (2022)
In patients with slowly progressive spastic paraparesis, the differential diagnosis of primary progressive multiple sclerosis (PPMS) and hereditary spastic paraplegia (HSP) can be challenging. Serum neurofilament light chain (sNfL) and glial fibrilla
Externí odkaz:
https://doaj.org/article/8428480981884e6499e1249c0b6d8d0e
Autor:
Moritz Klawitter, Ali El-Ayoubi, Jasmin Buch, Jakob Rüttinger, Maximilian Ehrenfeld, Eva Lichtenegger, Marcel A. Krüger, Klaus Mantwill, Florestan J. Koll, Markus C. Kowarik, Per Sonne Holm, Ulrike Naumann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9965 (2022)
Glioblastoma (GBM) is an obligatory lethal brain tumor with a median survival, even with the best standard of care therapy, of less than 20 months. In light of this fact, the evaluation of new GBM treatment approaches such as oncolytic virotherapy (O
Externí odkaz:
https://doaj.org/article/2bccc9be5b9f4de8a42dfc2ee745ba5e
Publikováno v:
Neurological Research and Practice, Vol 1, Iss 1, Pp 1-7 (2019)
Abstract Multiple sclerosis (MS) and human immunodeficiency virus (HIV) infection are frequent and well-studied nosological entities. Yet, comorbidity of MS and HIV has only been rarely reported in the medical literature. We conducted a literature se
Externí odkaz:
https://doaj.org/article/8649bebd161a44798689c3b6a458c357
Autor:
Christoph Ruschil, Gisela Gabernet, Gildas Lepennetier, Simon Heumos, Miriam Kaminski, Zsuzsanna Hracsko, Martin Irmler, Johannes Beckers, Ulf Ziemann, Sven Nahnsen, Gregory P. Owens, Jeffrey L. Bennett, Bernhard Hemmer, Markus C. Kowarik
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Double negative (DN) (CD19+CD20lowCD27-IgD-) B cells are expanded in patients with autoimmune and infectious diseases; however their role in the humoral immune response remains unclear. Using systematic flow cytometric analyses of peripheral blood B
Externí odkaz:
https://doaj.org/article/5a236f60fdc947218c69d356a5dca781
Autor:
Ahmed Abdelhak, Andre Huss, Alexander Stahmann, Makbule Senel, Markus Krumbholz, Markus C. Kowarik, Joachim Havla, Tania Kümpfel, Ingo Kleiter, Isabella Wüstinger, Uwe K. Zettl, Margit Schwartz, Romy Roesler, Tim Friede, Albert C. Ludolph, Ulf Ziemann, Hayrettin Tumani
Publikováno v:
Contemporary Clinical Trials Communications, Vol 18, Iss , Pp 100574- (2020)
Background: Defining clinical and subclinical progression in multiple sclerosis (MS) is challenging. Patient history, expanded disability status scale (EDSS), and magnetic resonance imaging (MRI) all have shortcomings and may underestimate disease dy
Externí odkaz:
https://doaj.org/article/46666c1d554343f685ebfa50cc99b728