Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Markus B. Geuking"'
Autor:
Regula Burkhard, Mia Koegler, Kirsty Brown, Kirsten Wilson, Lukas F. Mager, Amanda Z. Zucoloto, Carolyn Thomson, Roopa Hebbandi Nanjundappa, Isla Skalosky, Shokouh Ahmadi, Braedon McDonald, Markus B. Geuking
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Healthy host-microbial mutualism with our intestinal microbiota relies to a large degree on compartmentalization and careful regulation of adaptive mucosal and systemic anti-microbial immune responses. However, commensal intestinal bacteria are never
Externí odkaz:
https://doaj.org/article/21972fc020164b9eba64f2065e45d74f
Autor:
Amanda Z. Zucoloto, Jared Schlechte, Aline Ignacio, Carolyn A. Thomson, Shannon Pyke, Ian-ling Yu, Markus B. Geuking, Kathy D. McCoy, Bryan G. Yipp, Mark R. Gillrie, Braedon McDonald
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112507- (2023)
Summary: During bloodstream infections, neutrophils home to the liver as part of an intravascular immune response to eradicate blood-borne pathogens, but the mechanisms regulating this crucial response are unknown. Using in vivo imaging of neutrophil
Externí odkaz:
https://doaj.org/article/00bd9fb6e81e42afa4bb4ea92accb295
Autor:
Nicolas Esquerre, Lilian Basso, Manon Defaye, Fernando A. Vicentini, Nina Cluny, Dominique Bihan, Simon A. Hirota, Alana Schick, Humberto B. Jijon, Ian A. Lewis, Markus B. Geuking, Keith A. Sharkey, Christophe Altier, Yasmin Nasser
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 2, Pp 225-244 (2020)
Background & Aims: Despite achieving endoscopic remission, more than 20% of inflammatory bowel disease patients experience chronic abdominal pain. These patients have increased rectal transient receptor potential vanilloid-1 receptor (TRPV1) expressi
Externí odkaz:
https://doaj.org/article/3b3125c1bc7c426db3bc2c65793c4a10
Autor:
Angelina De Martin, Mechthild Lütge, Yves Stanossek, Céline Engetschwiler, Jovana Cupovic, Kirsty Brown, Izadora Demmer, Martina A. Broglie, Markus B. Geuking, Wolfram Jochum, Kathy D. McCoy, Sandro J. Stoeckli, Burkhard Ludewig
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Squamous cell carcinoma of the tonsil is one of the most frequent cancers of the oropharynx. The escalating rate of tonsil cancer during the last decades is associated with the increase of high risk-human papilloma virus (HR-HPV) infections. While th
Externí odkaz:
https://doaj.org/article/08e6db797f574e05b81a6fa907dfb228
Autor:
Madeleine Wyss, Kirsty Brown, Carolyn A. Thomson, Mia Koegler, Fernanda Terra, Vina Fan, Francesca Ronchi, Dominique Bihan, Ian Lewis, Markus B. Geuking, Kathy D. McCoy
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Early life exposure to microbes plays an important role in immune system development. Germ-free mice, or mice colonized with a low-diversity microbiota, exhibit high serum IgE levels. An increase in microbial richness, providing it occurs in a critic
Externí odkaz:
https://doaj.org/article/466d0c87b5aa46ee83fef24ddec54f99
Autor:
Lisa Perruzza, Giorgio Gargari, Michele Proietti, Bruno Fosso, Anna Maria D’Erchia, Caterina Elisa Faliti, Tanja Rezzonico-Jost, Daniela Scribano, Laura Mauri, Diego Colombo, Giovanni Pellegrini, Annalisa Moregola, Catherine Mooser, Graziano Pesole, Mauro Nicoletti, Giuseppe Danilo Norata, Markus B. Geuking, Kathy D. McCoy, Simone Guglielmetti, Fabio Grassi
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2566-2575 (2017)
The ATP-gated ionotropic P2X7 receptor regulates T follicular helper (Tfh) cell abundance in the Peyer’s patches (PPs) of the small intestine; deletion of P2rx7, encoding for P2X7, in Tfh cells results in enhanced IgA secretion and binding to comme
Externí odkaz:
https://doaj.org/article/393daf25202c4bef9be01d20883d157a
Publikováno v:
Mucosal immunology. 15(5)
Despite compartmentalization within the lumen of the gastrointestinal tract, the gut microbiota has a far-reaching influence on immune cell development and function throughout the body. This long-distance relationship is crucial for immune homeostasi
Autor:
Marco Gallo, Ryan A. Groves, Nicola Pett, Kathy D. McCoy, Seungil Paik, Noah C. A. Cooke, Hena R. Ramay, Kirsty Brown, Ian A. Lewis, Lukas F. Mager, John Stagg, Regula Burkhard, Markus B. Geuking
Publikováno v:
Science. 369:1481-1489
Inosine modulates antitumor immunity Checkpoint blockade immunotherapy harnesses the immune system to kill cancer cells and has been used with great success to treat certain tumors, but not all cancer patients respond. The efficacy of checkpoint bloc
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(4)
The intestinal microbiota is critical for the development of gut-associated lymphoid tissues, including Peyer's patches and mesenteric lymph nodes, and is instrumental in educating the local as well as systemic immune system. In addition, it also imp
Autor:
Cristina Gil-Cruz, Lucas Onder, Lukas Flatz, Valérie Boivin-Jahns, Catherine Mooser, Emma Slack, Burkhard Ludewig, Madeleine Wyss, Mechthild Lütge, Micha T. Maeder, Markus Arnoldini, Markus B. Geuking, Mario Novkovic, Roland Jahns, Hans Rickli, Rebekka Niederer, Francesca Ronchi, Katrien Van der Borght, Angelina De Martin, Christian Perez-Shibayama, Gustavo Campos Ramos, Bart N. Lambrecht, Urs Eriksson, Kathy D. McCoy, Veronika Nindl
Publikováno v:
Science. 366:881-886
Peptide mimicry breaks the heart Myocarditis, a prolonged chronic inflammation of heart muscle, can eventually progress to inflammatory cardiomyopathy, a serious condition associated with heart failure. Activated T helper (T H ) cells that recognize