Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Markus Böhl"'
Autor:
Anne Jäger, Célia Risacher, Hans-Joachim Knölker, Herwig O. Gutzeit, Dietmar J. Manstein, René Martin, Arndt W. Schmidt, Krishna Chinthalapudi, Matthias Preller, Sabine Richter, Markus Böhl, André Barthel
Publikováno v:
European Journal of Organic Chemistry. 2014:4487-4505
The pentahalogenated 2-arylpyrrole-type alkaloids pentabromopseudilin and pentachloropseudilin represent a new class of isoform-specific allosteric inhibitors of myosin ATPase. Herein, we describe an application of the silver(I)-catalyzed cycloisomer
Autor:
Sabine Richter, Roman Fedorov, Markus Böhl, Hans-Joachim Knölker, Kerstin E. Knott, Konstanze K. Gruner, René Martin, Ronny Forke, Herwig O. Gutzeit, Georgios Tsiavaliaris, Sameer Agarwal, Dietmar J. Manstein, Stefan Auschill
Publikováno v:
Pure and Applied Chemistry. 82:1975-1991
We have developed efficient synthetic routes to heterocyclic ring systems using transition metals (palladium, iron, and silver). Recent applications of this chemistry to the total synthesis of biologically active alkaloids include carbazole alkaloids
Autor:
Sabine Richter, Herwig O. Gutzeit, Roman Fedorov, Hans-Joachim Knölker, Anne Jäger, Markus Böhl, Dietmar J. Manstein, René Martin
Publikováno v:
Angewandte Chemie International Edition. 48:8042-8046
Autor:
Markus Böhl, Bernd Schwenzer
Publikováno v:
Chemical Biology & Drug Design. 69:212-215
We compared an antisense-oligodeoxynucleotide and four DNAzymes directed to the prothrombin mRNA for their efficiency to reduce prothrombin transcript level in HepG2 cells. The DNAzymes have different binding arm symmetry and cleavage sites, but are
Autor:
Matthias Preller, Krishna Chinthalapudi, Dietmar J. Manstein, Célia Risacher, Markus Böhl, Arndt W. Schmidt, Herwig O. Gutzeit, André Barthel, Sabine Richter, Anne Jäger, René Martin, Hans-Joachim Knölker
Publikováno v:
European Journal of Organic Chemistry. 2014
Publikováno v:
Analytical Biochemistry. 359:280-282
Autor:
Herwig O. Gutzeit, Markus Böhl
Publikováno v:
ACS Symposium Series ISBN: 9780841269828
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c94f535391b819409f42055c01ccd0a
https://doi.org/10.1021/bk-2008-0993.ch004
https://doi.org/10.1021/bk-2008-0993.ch004
Autor:
Herwig O. Gutzeit, Hans-Joachim Knölker, Bernhard Brenner, Falk K. Hartmann, Dietmar J. Manstein, P. Baruch, Roman Fedorov, René Martin, Markus Böhl, Georgios Tsiavaliaris, Manuel H. Taft
Publikováno v:
Nature structural & molecular biology 16(1), 80-88 (2009). doi:10.1038/nsmb.1542
Nature structural & molecular biology 16(1), 80-88 (2009). doi:10.1038/nsmb.1542
Published by Nature Publishing Group, London [u.a.]
Published by Nature Publishing Group, London [u.a.]
Autor:
Andrea Sokoll, Markus Böhl, Sineej Madathil, Karim Fahmy, Simon Tietze, Joannis Apostolakis, Frank Pfennig, Herwig O. Gutzeit
Publikováno v:
Biophysical Journal 93(2007), 2765-2780
Based on the identification of actin as a target protein for the flavonol quercetin, the binding affinities of quercetin and structurally related flavonoids were determined by flavonoid-dependent quenching of tryptophan fluorescence from actin. Irres
Mechanism of inhibition of human secretory phospholipase A2 by flavonoids: rationale for lead design
Autor:
M. Teresa Pisabarro, Mario Menschikowski, Herwig O. Gutzeit, Petra Fischer, Peter Metz, Markus Böhl, Claudia Tietböhl, Jens Lättig, Sandra Tischer
Publikováno v:
Journal of computer-aided molecular design. 21(8)
The human secretory phospholipase A2 group IIA (PLA2-IIA) is a lipolytic enzyme. Its inhibition leads to a decrease in eicosanoids levels and, thereby, to reduced inflammation. Therefore, PLA2-IIA is of high pharmacological interest in treatment of c