Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Markus Bänziger"'
Publikováno v:
Organic Process Research & Development. 19:1428-1433
The electrochemical 2-fold dehalogenation of a spirocyclopropane-proline derivative at leaded bronze was scaled-up in a divided batch-type electrolysis cell in good yield and excellent selectivity. The upscaling via a flow electrolysis cell was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b43c5cf78d1283b94ef1fde20606f3d
https://doi.org/10.1021/acs.oprd.5b00272
https://doi.org/10.1021/acs.oprd.5b00272
Autor:
Christoph Bucher, Markus Bänziger, Christina Römelt, Siegfried R. Waldvogel, Fabrice Gallou, Maximilian Selt, Christoph Gütz, Tomás R. Galvão, Nadine Hecken
Publikováno v:
Chemistry – A European Journal. 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb7b3275e80e42e68406614fdf63918
https://doi.org/10.1002/chem.201584061
https://doi.org/10.1002/chem.201584061
Autor:
Christina Römelt, Christoph Bucher, Christoph Gütz, Nadine Hecken, Fabrice Gallou, Siegfried R. Waldvogel, Tomás R. Galvão, Maximilian Selt, Markus Bänziger
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 21(40)
Leaded bronze turned out to be an excellent cathode material for the dehalogenation reaction of cyclopropanes without affecting the strained molecular entity. With this particular alloy, beneficial properties of lead cathodes are conserved, whereas t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272bbd35d0132a6a51eca2716229fcb2
https://pubmed.ncbi.nlm.nih.gov/26250701
https://pubmed.ncbi.nlm.nih.gov/26250701
Autor:
David Bryant Batt, Run-Ming B. Wang, Peng Geng, Markus Bänziger, Tim Ramsey, Lawrence Blas Perez, Francis Taplin, Richard William Versace, David Cesarz, Wolfgang Marterer, Walter Michael, Naeem Yusuff, Donatienne Denni-Dischert
Publikováno v:
Organic Process Research & Development. 10:70-77
A scaleable synthetic route to [4,7‘]bis-isoquinolinyl-1-yl-(2-tert-butyl-pyrimidine-5-yl)amine (1), an inhibitor of B-Raf kinase is described. The key step in the synthesis is the Pd-catalyzed Negishi coupling of 4-bromo-1-chloroisoquinoline with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b5919fa44d0475d8f4170643a35afec
https://doi.org/10.1021/op0501601
https://doi.org/10.1021/op0501601
Publikováno v:
Organic Process Research & Development. 7:904-912
Different synthetic routes to the enantiomerically pure octahydrobenzo[g]quinoline derivative JNZ092 were evaluated for their suitability to rapidly prepare a first clinical batch on a kilogram scale. On the basis of the experience of previous octahy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1fc6db0b2c5e8f3f17728465f44f092
https://doi.org/10.1021/op034112x
https://doi.org/10.1021/op034112x
Autor:
Markus Bänziger, Hans Hirt, Christophe Malan, Kurt Laumen, Troxler Thomas J, Felix Spindler, Jacques Cercus, Fritz Struber
Publikováno v:
Tetrahedron: Asymmetry. 14:3469-3477
The decahydroisoquinoline derivative NVP-ACQ090 is a potent and selective antagonist at the somatostatin sst3 receptor. The original research synthesis of NVP-ACQ090 comprises a main chain of nine linear steps and two side chains of three and steps,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26306db1c8d1fba3cf32e2702b077d42
https://doi.org/10.1016/j.tetasy.2003.07.024
https://doi.org/10.1016/j.tetasy.2003.07.024
Publikováno v:
Organic Process Research & Development. 4:460-466
3- Substituted octahydrobenzo[g]quinolines are important intermediates for pharmaceutically active compounds. A short, efficient synthesis, which is feasible for large-scale manufacturing of rac-(3S,4aR,10aR)-6-methoxy-1-propyl-1,2,3,4,4a,5,10,10a-oc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a4adbc9a3950e206e3e5218bba8f5c2
https://doi.org/10.1021/op0000531
https://doi.org/10.1021/op0000531
Publikováno v:
Helvetica Chimica Acta. 81:729-733
An alternative synthesis of enantiomerically pure SDZ 220–881 (1a) and SDZ EAB 515 (1b) starting from L-Z-tyrosine is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726d5fca85e6f448498c04a208f255bb
https://doi.org/10.1002/hlca.19980810322
https://doi.org/10.1002/hlca.19980810322
Publikováno v:
Tetrahedron: Asymmetry. 4:723-726
(2R,3E)-4-Iodobut-3-en-2-ol ((R)-1 and (2S,3E)-4-Iodobut-3-en-2-yl chloroacetate ((S)-7) of high enantiomeric purity can be prepared by a lipase catalysed kinetic resolution of racemic (E)-4-Iodobut-3-en-2-yl chloroacetate (7). The alcohol (R)-1 can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::115e3c8c8d7cbab499d6baa43d6a35fb
https://doi.org/10.1016/s0957-4166(00)80180-9
https://doi.org/10.1016/s0957-4166(00)80180-9
Publikováno v:
Helvetica Chimica Acta. 75:892-900
The title compund, 1a, has been synthesised in racemic form from ethyl (E)-4-chloro-3-ethoxybut-2-enoate in 43% overall yield in five steps. Several routes to the final product are described, but the most efficient involves hydrogenation of a C(5)-un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f409ae520c4fe495f172637dbcfcf4e9
https://doi.org/10.1002/hlca.19920750323
https://doi.org/10.1002/hlca.19920750323