Novel genetic loci affecting facial shape variation in humans

Autor: Ziyi Xiong, Gabriela Dankova, Laurence J Howe, Myoung Keun Lee, Pirro G Hysi, Markus A de Jong, Gu Zhu, Kaustubh Adhikari, Dan Li, Yi Li, Bo Pan, Eleanor Feingold, Mary L Marazita, John R Shaffer, Kerrie McAloney, Shu-Hua Xu, Li Jin, Sijia Wang, Femke MS de Vrij, Bas Lendemeijer, Stephen Richmond, Alexei Zhurov, Sarah Lewis, Gemma C Sharp, Lavinia Paternoster, Holly Thompson, Rolando Gonzalez-Jose, Maria Catira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Giovanni Poletti, Gabriel Bedoya, Francisco Rothhammer, André G Uitterlinden, M Arfan Ikram, Eppo Wolvius, Steven A Kushner, Tamar EC Nijsten, Robert-Jan TS Palstra, Stefan Boehringer, Sarah E Medland, Kun Tang, Andres Ruiz-Linares, Nicholas G Martin, Timothy D Spector, Evie Stergiakouli, Seth M Weinberg, Fan Liu, Manfred Kayser, On behalf of the International Visible Trait Genetics (VisiGen) Consortium

Publikováno v: eLife, Vol 8 (2019)

The human face represents a combined set of highly heritable phenotypes, but knowledge on its genetic architecture remains limited, despite the relevance for various fields. A series of genome-wide association studies on 78 facial shape phenotypes qu

Externí odkaz: https://doaj.org/article/cb141e48e70148ee8bc2e91adf5b6c6e

Author response: Novel genetic loci affecting facial shape variation in humans

Autor: Yi Li, Andres Ruiz-Linares, Li Jin, Stephen Richmond, Francisco Rothhammer, Myoung Keun Lee, Gabriela Dankova, Dan Li, Laurence J. Howe, Sarah E. Medland, Carla Gallo, Kun Tang, Evie Stergiakouli, Robert-Jan Ts Palstra, Alexei I. Zhurov, Ziyi Xiong, Seth M. Weinberg, Nicholas G. Martin, Mary L. Marazita, Eppo B. Wolvius, Eleanor Feingold, Shuhua Xu, Sarah J Lewis, Pirro G. Hysi, Gu Zhu, Gemma C Sharp, Lavinia Paternoster, Maria Cátira Bortolini, Manfred Kayser, André G. Uitterlinden, Sijia Wang, Rolando González-José, Fan Liu, Kaustubh Adhikari, Steven A. Kushner, Tamar Nijsten, Holly Thompson, Giovanni Poletti, Stefan Boehringer, Kerrie McAloney, Femke M.S. de Vrij, M. Arfan Ikram, Bo Pan, John R. Shaffer, Tim D. Spector, Gabriel Bedoya, Markus A. de Jong, Bas Lendemeijer, Samuel Canizales-Quinteros

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c724043f9f2d847ef953079dc540ee5e
https://doi.org/10.7554/elife.49898.sa2

Ensemble landmarking of 3D facial surface scans

Autor: Wiro J. Niessen, Maarten J. Koudstaal, Pirro G. Hysi, Markus A. de Jong, Tim D. Spector, Eppo B. Wolvius, Manfred Kayser, Stefan Böhringer

Publikováno v: Scientific Reports, 8(1)
Scientific Reports, 8:12. Nature Publishing Group
Scientific Reports
Scientific Reports, 8
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Landmarking of 3D facial surface scans is an important analysis step in medical and biological applications, such as genome-wide association studies (GWAS). Manual landmarking is often employed with considerable cost and rater dependent variability.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341051a38161304f49bbbc3aa5a60f4d
http://resolver.tudelft.nl/uuid:7486481e-1e2e-4233-97c7-e122cc5d1cf6

Automated human skull landmarking with 2D Gabor wavelets

Autor: Maarten J. Koudstaal, Eppo B. Wolvius, Manfred Kayser, Jan Pieter de Gijt, Atilla Gül, Stefan Böhringer, Markus A. de Jong

Publikováno v: Physics in Medicine and Biology, 63(10):105011. IOP Publishing Ltd.

Landmarking of CT scans is an important step in the alignment of skulls that is key in surgery planning, pre-/post-surgery comparisons, and morphometric studies. We present a novel method for automatically locating anatomical landmarks on the surface

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423ff96290a443441ac35dc2f3113bb8
https://doi.org/10.1088/1361-6560/aabfa0