Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Markus, Landthaler"'
Autor:
Morgan Essex, Belén Millet Pascual-Leone, Ulrike Löber, Mathias Kuhring, Bowen Zhang, Ulrike Brüning, Raphaela Fritsche-Guenther, Marta Krzanowski, Facundo Fiocca Vernengo, Sophia Brumhard, Ivo Röwekamp, Agata Anna Bielecka, Till Robin Lesker, Emanuel Wyler, Markus Landthaler, Andrej Mantei, Christian Meisel, Sandra Caesar, Charlotte Thibeault, Victor M. Corman, Lajos Marko, Norbert Suttorp, Till Strowig, Florian Kurth, Leif E. Sander, Yang Li, Jennifer A. Kirwan, Sofia K. Forslund, Bastian Opitz
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract The clinical course of COVID-19 is variable and often unpredictable. To test the hypothesis that disease progression and inflammatory responses associate with alterations in the microbiome and metabolome, we analyzed metagenome, metabolome,
Externí odkaz:
https://doaj.org/article/3800ac4d0de04e14b83d18bba159a41d
Autor:
Vincent D. Friedrich, Peter Pennitz, Emanuel Wyler, Julia M. Adler, Dylan Postmus, Kristina Müller, Luiz Gustavo Teixeira Alves, Julia Prigann, Fabian Pott, Daria Vladimirova, Thomas Hoefler, Cengiz Goekeri, Markus Landthaler, Christine Goffinet, Antoine-Emmanuel Saliba, Markus Scholz, Martin Witzenrath, Jakob Trimpert, Holger Kirsten, Geraldine Nouailles
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105312- (2024)
Summary: Background: Translating findings from animal models to human disease is essential for dissecting disease mechanisms, developing and testing precise therapeutic strategies. The coronavirus disease 2019 (COVID-19) pandemic has highlighted this
Externí odkaz:
https://doaj.org/article/550b504cdf1443abbb5bb72c0b333a6c
Autor:
Philipp Trepte, Christopher Secker, Julien Olivet, Jeremy Blavier, Simona Kostova, Sibusiso B Maseko, Igor Minia, Eduardo Silva Ramos, Patricia Cassonnet, Sabrina Golusik, Martina Zenkner, Stephanie Beetz, Mara J Liebich, Nadine Scharek, Anja Schütz, Marcel Sperling, Michael Lisurek, Yang Wang, Kerstin Spirohn, Tong Hao, Michael A Calderwood, David E Hill, Markus Landthaler, Soon Gang Choi, Jean-Claude Twizere, Marc Vidal, Erich E Wanker
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 4, Pp 428-457 (2024)
Abstract Protein–protein interactions (PPIs) offer great opportunities to expand the druggable proteome and therapeutically tackle various diseases, but remain challenging targets for drug discovery. Here, we provide a comprehensive pipeline that c
Externí odkaz:
https://doaj.org/article/bd1c8039d8764608818fd46023e76135
Autor:
Emanuel Wyler, Chris Lauber, Artür Manukyan, Aylina Deter, Claudia Quedenau, Luiz Gustavo Teixeira Alves, Claudia Wylezich, Tatiana Borodina, Stefan Seitz, Janine Altmüller, Markus Landthaler
Publikováno v:
Environment International, Vol 190, Iss , Pp 108875- (2024)
Wastewater contains an extensive reservoir of genetic information, yet largely unexplored. Here, we analyzed by high-throughput sequencing total nucleic acids extracted from wastewater samples collected during a 17 month-period in Berlin, Germany. By
Externí odkaz:
https://doaj.org/article/977e07925ec5407ca63fc2b9ce9ce81e
Autor:
Kristin Metzdorf, Henning Jacobsen, Yeonsu Kim, Luiz Gustavo Teixeira Alves, Upasana Kulkarni, Maja Cokarić Brdovčak, Jelena Materljan, Kathrin Eschke, M. Zeeshan Chaudhry, Markus Hoffmann, Federico Bertoglio, Maximilian Ruschig, Michael Hust, Marko Šustić, Astrid Krmpotić, Stipan Jonjić, Marek Widera, Sandra Ciesek, Stefan Pöhlmann, Markus Landthaler, Luka Čičin-Šain
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Current vaccines against COVID-19 elicit immune responses that are overall strong but wane rapidly. As a consequence, the necessary booster shots have contributed to vaccine fatigue. Hence, vaccines that would provide lasting protection against COVID
Externí odkaz:
https://doaj.org/article/ff2f6e1930ef4cf194f3fd3eb6aefaa4
Autor:
Luiz Gustavo Teixeira Alves, Morris Baumgardt, Christine Langner, Mara Fischer, Julia Maria Adler, Judith Bushe, Theresa Catharina Firsching, Guido Mastrobuoni, Jenny Grobe, Katja Hoenzke, Stefan Kempa, Achim Dieter Gruber, Andreas Christian Hocke, Jakob Trimpert, Emanuel Wyler, Markus Landthaler
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Introduction The emergence of new SARS-CoV-2 variants, capable of escaping the humoral immunity acquired by the available vaccines, together with waning immunity and vaccine hesitancy, challenges the efficacy of the vaccination strategy in fighting C
Externí odkaz:
https://doaj.org/article/7bc3d616ad524edc9f22f4996010cf8c
Autor:
Stefan Peidli, Geraldine Nouailles, Emanuel Wyler, Julia M. Adler, Sandra Kunder, Anne Voß, Julia Kazmierski, Fabian Pott, Peter Pennitz, Dylan Postmus, Luiz Gustavo Teixeira Alves, Christine Goffinet, Achim D. Gruber, Nils Blüthgen, Martin Witzenrath, Jakob Trimpert, Markus Landthaler, Samantha D. Praktiknjo
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114328- (2024)
Summary: A key issue for research on COVID-19 pathogenesis is the lack of biopsies from patients and of samples at the onset of infection. To overcome these hurdles, hamsters were shown to be useful models for studying this disease. Here, we further
Externí odkaz:
https://doaj.org/article/c99d11239614470a8f8f7a476d42cda0
Autor:
Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Rebekka Rust, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Büttnerova, Alexandra Förster, Derya Cengiz, Luiz Gustavo Teixeira Alves, Julia Schneider, Claudia Kedor, Judith Bellmann-Strobl, Aminaa Sanchin, Hans-Hilmar Goebel, Markus Landthaler, Victor Corman, Andreas Roos, Frank L. Heppner, Helena Radbruch, Friedemann Paul, Carmen Scheibenbogen, Nora F. Dengler, Werner Stenzel
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract The SARS-CoV-2 pandemic not only resulted in millions of acute infections worldwide, but also in many cases of post-infectious syndromes, colloquially referred to as “long COVID”. Due to the heterogeneous nature of symptoms and scarcity
Externí odkaz:
https://doaj.org/article/b65fc0fea9634e6a9d9eb0b43f7c5637
Autor:
Haiyue Liu, Roberto Arsiè, Daniel Schwabe, Marcel Schilling, Igor Minia, Jonathan Alles, Anastasiya Boltengagen, Christine Kocks, Martin Falcke, Nir Friedman, Markus Landthaler, Nikolaus Rajewsky
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 10, Pp 1-23 (2023)
Abstract RNA abundance is tightly regulated in eukaryotic cells by modulating the kinetic rates of RNA production, processing, and degradation. To date, little is known about time-dependent kinetic rates during dynamic processes. Here, we present SLA
Externí odkaz:
https://doaj.org/article/25cb9d37b1464e73a48853d888e495de
Autor:
Guorong Sun, Kai Alexander Kropp, Marieluise Kirchner, Nina Plückebaum, Anton Selich, Manutea Serrero, Akshay Dhingra, Jorge Rubén Cabrera, Birgit Ritter, Rudolf Bauerfeind, Emanuel Wyler, Markus Landthaler, Axel Schambach, Beate Sodeik, Philipp Mertins, Abel Viejo-Borbolla
Publikováno v:
mBio, Vol 15, Iss 2 (2024)
ABSTRACT The highly prevalent herpes simplex virus type 1 (HSV-1) causes a range of diseases, including cold sores, blinding keratitis, and life-threatening encephalitis. HSV-1 initially replicates in epithelial cells, enters the peripheral nervous s
Externí odkaz:
https://doaj.org/article/b03f18e16aa44eca859b26cb7c0b5163