Growth of Renal Cancer Cell Lines Is Strongly Inhibited by Synergistic Activity of Low-Dosed Amygdalin and Sulforaphane.

Autor: Markowitsch SD; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Pham T; Department of Urology, Goethe-University, 60590 Frankfurt am Main, Germany., Rutz J; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Chun FK; Department of Urology, Goethe-University, 60590 Frankfurt am Main, Germany., Haferkamp A; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Tsaur I; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Juengel E; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Ries N; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Thomas A; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany., Blaheta RA; Department of Urology and Pediatric Urology, University Medical Center Mainz, 55131 Mainz, Germany.

Publikováno v: Nutrients [Nutrients] 2024 Oct 31; Vol. 16 (21). Date of Electronic Publication: 2024 Oct 31.

Targeting the glutamine metabolism to suppress cell proliferation in mesenchymal docetaxel-resistant prostate cancer.

Autor: Beier AK; Department of Urology, Technische Universität Dresden, Dresden, Germany., Ebersbach C; Department of Urology, Technische Universität Dresden, Dresden, Germany., Siciliano T; Department of Urology, Technische Universität Dresden, Dresden, Germany., Scholze J; Department of Urology, Technische Universität Dresden, Dresden, Germany., Hofmann J; Department of Urology, Technische Universität Dresden, Dresden, Germany., Hönscheid P; Institute of Pathology, Universitätsklinikum Carl Gustav Carus Dresden, 01307, Dresden, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany., Baretton GB; Institute of Pathology, Universitätsklinikum Carl Gustav Carus Dresden, 01307, Dresden, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany., Woods K; IIIrd Department of Medicine - Hematology & Oncology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Guezguez B; IIIrd Department of Medicine - Hematology & Oncology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.; German Cancer Consortium (DKTK), Heidelberg, Germany., Dubrovska A; OncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; National Center for Tumor Diseases (NCT), Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Helmholtz-Zentrum Dresden-Rossendorf (HZDR), Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden and German Cancer Research Center (DKFZ), Dresden, Germany., Markowitsch SD; Department of Urology and Pediatric Urology, University Medical Center Mainz, Mainz, Germany., Thomas C; Department of Urology, Technische Universität Dresden, Dresden, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, Dresden, Germany., Puhr M; Medical University of Innsbruck, Department of Urology, 6020, Innsbruck, Austria., Erb HHH; Department of Urology, Technische Universität Dresden, Dresden, Germany. holger.erb@uniklinikum-dresden.de.

Publikováno v: Oncogene [Oncogene] 2024 Jun; Vol. 43 (26), pp. 2038-2050. Date of Electronic Publication: 2024 May 15.

Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A).

Autor: Schmelter C; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Fomo KN; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Brueck A; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Perumal N; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Markowitsch SD; Department of Urology and Pediatric Urology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Govind G; Institute of Physics, Johannes Gutenberg University, 55131 Mainz, Germany., Speck T; Institute of Physics, Johannes Gutenberg University, 55131 Mainz, Germany., Pfeiffer N; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany., Grus FH; Department of Experimental and Translational Ophthalmology, University Medical Center, Johannes Gutenberg University, 55131 Mainz, Germany.

Publikováno v: Biomolecules [Biomolecules] 2023 Jul 22; Vol. 13 (7). Date of Electronic Publication: 2023 Jul 22.

Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway.

Autor: Markowitsch SD; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Vakhrusheva O; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Schupp P; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Akele Y; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Kitanovic J; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Slade KS; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Efferth T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, 55128 Mainz, Germany., Thomas A; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Tsaur I; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Mager R; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Haferkamp A; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Juengel E; Department of Urology and Pediatric Urology, University Medical Center Mainz, Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2022 Feb 22; Vol. 14 (5). Date of Electronic Publication: 2022 Feb 22.

Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis.

Autor: Markowitsch SD; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Juetter KM; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Schupp P; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Hauschulte K; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Vakhrusheva O; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Slade KS; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Thomas A; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Tsaur I; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Cinatl J Jr; Institute of Medical Virology, Goethe-University, 60596 Frankfurt, Germany., Michaelis M; Industrial Biotechnology Centre and School of Biosciences, University of Kent, Canterbury CT2 7NJ, UK., Efferth T; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, 55128 Mainz, Germany., Haferkamp A; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany., Juengel E; Department of Urology and Pediatric Urology, University Medical Center Mainz, Langenbeckstraße 1, 55131 Mainz, Germany.

Publikováno v: Cancers [Cancers (Basel)] 2021 Feb 20; Vol. 13 (4). Date of Electronic Publication: 2021 Feb 20.