Zobrazeno 1 - 10
of 360
pro vyhledávání: '"Markolf Hanefeld"'
Publikováno v:
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-9 (2017)
Abstract Background Dyslipidaemia is a major contributor to the increased risk of cardiovascular disease (CVD) associated with type 2 diabetes (T2D). This study aimed to characterize the extent of lipid-lowering therapy use and its impact on lipid an
Externí odkaz:
https://doaj.org/article/0c83b953299b40d7923e5049c18f0db5
Publikováno v:
SAGE Open Medical Case Reports, Vol 7 (2019)
For obese type 2 diabetes patients, weight reduction is one of the most important measures but fails in most cases. Testosterone deficiency can be the reason for such failure. This case presents a 57-year-old man who was referred to a urologist due t
Externí odkaz:
https://doaj.org/article/14fcfc61f2e14fa4ae5bef34b88a5489
Autor:
Józef Drzewoski, Markolf Hanefeld
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 122 (2021)
Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become the medication with steadily increasing potential therapeutic ind
Externí odkaz:
https://doaj.org/article/c52177c55a0a42679fc2f61b89b5217e
Autor:
Sarah-Maria Krieger, Manja Reimann, Rocco Haase, Elena Henkel, Markolf Hanefeld, Tjalf Ziemssen
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Objective: The performance of the Sudoscan technology for diagnosing diabetic polyneuropathy (DPN) was evaluated against the quantitative sudomotor axon reflex test (QSART). Furthermore, the association of Sudoscan with two clinical neuropathy scorin
Externí odkaz:
https://doaj.org/article/68e1f9e5da0a4fc7b1712e90a84a7bb3
Autor:
Markolf Hanefeld, Katrin Engelmann, Dieter Appelt, Dirk Sandner, Ingo Weigmann, Xenia Ganz, Frank Pistrosch, Carsta Köhler, Antje Gasparic, Andreas L Birkenfeld
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0184234 (2017)
Increased levels of systemic vascular endothelial growth factors (VEGFs) in patients with diabetes are associated with increased risk of microvessel disease. On the other hand, low VEGF levels after intravitreal antibody application may be associated
Externí odkaz:
https://doaj.org/article/87ab875c2dc74d798b15091c9617f705
Autor:
Effrossyni Gkrania-Klotsas, Zheng Ye, Andrew J Cooper, Stephen J Sharp, Robert Luben, Mary L Biggs, Liang-Kung Chen, Kuppan Gokulakrishnan, Markolf Hanefeld, Erik Ingelsson, Wen-An Lai, Shih-Yi Lin, Lars Lind, Vitool Lohsoonthorn, Viswanathan Mohan, Antonio Muscari, Goran Nilsson, John Ohrvik, Jiang Chao Qiang, Nancy Swords Jenny, Koji Tamakoshi, Theodora Temelkova-Kurktschiev, Ya-Yu Wang, Chittaranjan Sakerlal Yajnik, Marco Zoli, Kay-Tee Khaw, Nita G Forouhi, Nicholas J Wareham, Claudia Langenberg
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13405 (2010)
Biological evidence suggests that inflammation might induce type 2 diabetes (T2D), and epidemiological studies have shown an association between higher white blood cell count (WBC) and T2D. However, the association has not been systematically investi
Externí odkaz:
https://doaj.org/article/3d87df69aa524c5fa75e8b6dfaf7ecb7
Autor:
Hana Koutnikova, Markku Laakso, Lu Lu, Roy Combe, Jussi Paananen, Teemu Kuulasmaa, Johanna Kuusisto, Hans-Ulrich Häring, Torben Hansen, Oluf Pedersen, Ulf Smith, Markolf Hanefeld, Robert W Williams, Johan Auwerx
Publikováno v:
PLoS Genetics, Vol 5, Iss 8, p e1000591 (2009)
Hypertension is a major health problem of largely unknown genetic origins. To identify new genes responsible for hypertension, genetic analysis of recombinant inbred strains of mice followed by human association studies might prove powerful and was e
Externí odkaz:
https://doaj.org/article/a50c5d06c7af4f11887e6bd170c3f874
Autor:
Elena Henkel, Markolf Hanefeld, Stefan R. Bornstein, Bernhard Schipp, Jan Sradnick, Frank Pistrosch, Andreas L. Birkenfeld, Dorothea Schipp, Jan B. Matschke, Ingo Weigmann
Publikováno v:
Diabetologia
Diabetologia, DOI: 10.1007/s00125-021-05562-9 (2021)
Diabetologia, DOI: 10.1007/s00125-021-05562-9 (2021)
Aims/hypothesis Individuals with type 2 diabetes mellitus and subclinical inflammation have stimulated coagulation, activated platelets and endothelial dysfunction. Recent studies with the direct factor Xa inhibitor rivaroxaban in combination with lo
Autor:
Matthew C. Riddle, Theodora Temelkova-Kurktschiev, Markolf Hanefeld, Wayne H-H Sheu, Ernesto Germán Cardona Muñoz, Hertzel C. Gerstein, Alvaro Avezum, William C. Cushman, Robert G. Hart, Rafael Diaz, Jan Basile, Nicolae Hancu, Helen M. Colhoun, Fady T. Botros, Fernando Lanas, Lars Rydén, Stephanie Hall, Patricio Lopez-Jaramillo, Lawrence A. Leiter, Petr Jansky, Jonathan E. Shaw, Matyas Keltai, Ignacio Conget, Mark Lakshmanan, Charles Atisso, Jeffrey L. Probstfield, Nana Pogosova, Peter J Raubenheimer, Leanne Dyal
Publikováno v:
The Lancet Diabetes & Endocrinology. 8:106-114
Summary Background Cardiovascular outcome trials have suggested that glucagon-like peptide 1 (GLP-1) receptor agonists might reduce strokes. We analysed the effect of dulaglutide on stroke within the researching cardiovascular events with a weekly in
Publikováno v:
Diabetologie und Stoffwechsel. 15:65-75
ZusammenfassungErhöhte Blutzucker- und Fettsäurespiegel schädigen die residuale B-Zell-Regeneration und -Funktion (Glukolipotoxizität) und vermindern die Insulinempfindlichkeit von Muskulatur, Fettgewebe, Leber und Endothel der Gefäßwand. Chron