Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Marko Z. Nikolić"'
Autor:
Puja Mehta, Blanca Sanz-Magallón Duque de Estrada, Emma K. Denneny, Kane Foster, Carolin T. Turner, Andreas Mayer, Martina Milighetti, Manuela Platé, Kaylee B. Worlock, Masahiro Yoshida, Jeremy S. Brown, Marko Z. Nikolić, Benjamin M. Chain, Mahdad Noursadeghi, Rachel C. Chambers, Joanna C. Porter, Gillian S. Tomlinson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPersistent radiological lung abnormalities are evident in many survivors of acute coronavirus disease 2019 (COVID-19). Consolidation and ground glass opacities are interpreted to indicate subacute inflammation whereas reticulation is though
Externí odkaz:
https://doaj.org/article/0c20d7c4f93849d0869626a0bd37c791
Autor:
Marko Z. Nikolić, Eva M. Garrido-Martin, Flavia R. Greiffo, Aurélie Fabre, Irene H. Heijink, Agnes Boots, Catherine M. Greene, Pieter S. Hiemstra, Sabine Bartel
Publikováno v:
ERJ Open Research, Vol 5, Iss 2 (2019)
The European Respiratory Society (ERS) International Congress is the largest respiratory congress and brings together leading experts in all fields of respiratory medicine and research. ERS Assembly 3 shapes the basic and translational science aspect
Externí odkaz:
https://doaj.org/article/e86366590b2e40949d063756584af245
Publikováno v:
Biology Open, Vol 7, Iss 4 (2018)
The airways are lined by secretory and multiciliated cells which function together to remove particles and debris from the respiratory tract. The transcriptome of multiciliated cells has been extensively studied, but the function of many of the genes
Externí odkaz:
https://doaj.org/article/d40f40b296834ce094d13b91c4d69e8b
Autor:
Rik G.H. Lindeboom, Kaylee B. Worlock, Lisa M. Dratva, Masahiro Yoshida, David Scobie, Helen R. Wagstaffe, Laura Richardson, Anna Wilbrey-Clark, Josephine L. Barnes, Krzysztof Polanski, Jessica Allen-Hyttinen, Puja Mehta, Dinithi Sumanaweera, Jacqueline Boccacino, Waradon Sungnak, Ni Huang, Lira Mamanova, Rakesh Kapuge, Liam Bolt, Elena Prigmore, Ben Killingley, Mariya Kalinova, Maria Mayer, Alison Boyers, Alex Mann, Vitor Teixeira, Sam M. Janes, Rachel C. Chambers, Muzlifah Haniffa, Andrew Catchpole, Robert Heyderman, Mahdad Noursadeghi, Benny Chain, Andreas Mayer, Kerstin B. Meyer, Christopher Chiu, Marko Z. Nikolić, Sarah A. Teichmann
The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the cellular disease dynamics remains limited. In our unique COVID-19 human challenge study we used single cell genomics of nasopharyngeal swabs and blood to temporall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d220950228bcc70a9b7e6d3734f32b9f
https://doi.org/10.1101/2023.04.13.23288227
https://doi.org/10.1101/2023.04.13.23288227
Autor:
Puja Mehta, Blanca Sanz-Magallón Duque de Estrada, Emma K Denneny, Kane Foster, Carolin T Turner, Andreas Mayer, Martina Milighetti, Manuela Platé, Kaylee B Worlock, Masahiro Yoshida, Jeremy S Brown, Marko Z Nikolić, Arjun Nair, Benjamin M Chain, Mahdad Noursadeghi, Rachel C Chambers, Joanna C Porter, Gillian S Tomlinson
RationalePersistent pulmonary sequelae are evident in many survivors of acute coronavirus disease 2019 (COVID-19) but the molecular mechanisms responsible are incompletely understood. Post-COVID radiological lung abnormalities comprise two broad cate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a9a38043410cc595cc35362b5a61e02
https://doi.org/10.1101/2023.03.28.23287759
https://doi.org/10.1101/2023.03.28.23287759
Autor:
Maximillian Woodall, Ana-Maria Cujba, Kaylee B. Worlock, Katie-Marie Case, Tereza Masonou, Masahiro Yoshida, Krzysztof Polanski, Ni Huang, Rik G. H. Lindeboom, Lira Mamanova, Liam Bolt, Laura Richardson, Samuel Ellis, Machaela Palor, Thomas Burgoyne, Andreia Pinto, Dale Moulding, Timothy D. McHugh, Aarash Saleh, Eliz Kilich, Puja Mehta, Chris O’Callaghan, Jie Zhou, Wendy Barclay, Paolo De Coppi, Colin R. Butler, Heloise Vinette, Sunando Roy, Judith Breuer, Rachel C. Chambers, Wendy E. Heywood, Kevin Mills, Robert E. Hynds, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić, Claire M. Smith
Children infected with SARS-CoV-2 rarely progress to respiratory failure, but the risk of mortality in infected people over 85 years of age remains high, despite vaccination and improving treatment options. Here, we take a comprehensive, multidiscipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d879062a84c842d555af5dd10e4eba88
https://doi.org/10.1101/2023.01.16.524211
https://doi.org/10.1101/2023.01.16.524211
Autor:
Josephine L. Barnes, Peng He, Masahiro Yoshida, Kaylee B. Worlock, Rik G.H. Lindeboom, Chenqu Suo, J. Patrick Pett, Anna Wilbrey-Clark, Emma Dann, Lira Mamanova, Laura Richardson, Amanda J. Oliver, Adam Pennycuick, Jessica Allen-Hyttinen, Iván T. Herczeg, Robert E. Hynds, Vitor H. Teixeira, Muzlifah Haniffa, Kyungtae Lim, Dawei Sun, Emma L. Rawlins, Krzysztof Polanski, Paul A. Lyons, John C. Marioni, Zewen Kelvin Tuong, Menna R. Clatworthy, James L. Reading, Sam M. Janes, Sarah A. Teichmann, Kerstin B. Meyer, Marko Z. Nikolić
During human development, lungs develop their roles of gas exchange and barrier function. Recent single cell studies have focused on epithelial and mesenchymal cell types, but much less is known about the developing lung immune cells, although the ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba9e470f99f21542bfed3c556bfdae9f
https://doi.org/10.1101/2022.12.13.519713
https://doi.org/10.1101/2022.12.13.519713
Autor:
Marko Z Nikolić, Oriol Caritg, Quitz Jeng, Jo-Anne Johnson, Dawei Sun, Kate J Howell, Jane L Brady, Usua Laresgoiti, George Allen, Richard Butler, Matthias Zilbauer, Adam Giangreco, Emma L Rawlins
Publikováno v:
eLife, Vol 6 (2017)
The embryonic mouse lung is a widely used substitute for human lung development. For example, attempts to differentiate human pluripotent stem cells to lung epithelium rely on passing through progenitor states that have only been described in mouse.
Externí odkaz:
https://doaj.org/article/3df32384189b4023bea988a27a860988
Autor:
Marko Z Nikolić, Emma L Rawlins
Publikováno v:
eLife, Vol 5 (2016)
Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.
Externí odkaz:
https://doaj.org/article/e9dd0bedb5634ec18ce13a9d3058b384
Autor:
Peng He, Kyungtae Lim, Dawei Sun, Jan Patrick Pett, Quitz Jeng, Krzysztof Polanski, Ziqi Dong, Liam Bolt, Laura Richardson, Lira Mamanova, Monika Dabrowska, Anna Wilbrey-Clark, Elo Madissoon, Zewen Kelvin Tuong, Emma Dann, Chenqu Suo, Isaac Goh, Masahiro Yoshida, Marko Z Nikolić, Sam M Janes, Xiaoling He, Roger A Barker, Sarah A Teichmann, John C. Marioni, Kerstin B Meyer, Emma L Rawlins
Publikováno v:
Cell. 185:4841-4860.e25
We present a multiomic cell atlas of human lung development that combines single cell RNA and ATAC sequencing, high throughput spatial transcriptomics and single cell imaging. Coupling single cell methods with spatial analysis has allowed a comprehen