Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marko Z, Nikolic"'
Autor:
Liam A. Hurst, Benjamin J. Dunmore, Lu Long, Alexi Crosby, Rafia Al-Lamki, John Deighton, Mark Southwood, Xudong Yang, Marko Z. Nikolic, Blanca Herrera, Gareth J. Inman, John R. Bradley, Amer A. Rana, Paul D. Upton, Nicholas W. Morrell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Reduced BMP receptor II signalling underlies pulmonary arterial hypertension (PAH). Here, Hurstet al. show that TNFα subverts BMP signalling by increasing BMP6 expression and signalling via an alternative BMP receptor, ALK2, in pulmonary artery smoo
Externí odkaz:
https://doaj.org/article/17874564742043b0848f710d036fb95a
Autor:
Josephine Barnes, Aidan T Hanrath, Louis C.S. Gardner, Stijn van Dongen, Anthony J. Rostron, Rik G.H. Lindeboom, Michael D Morgan, Justin Engelbert, Kenneth G. C. Smith, John C. Marioni, Berthold Göttgens, Caroline Wilson, Marko Z Nikolic, Andrew Barr, Zewen K. Tuong, Laura Jardine, Kerstin B Meyer, Eliz Kilich, Paul A Lyons, Elisa Laurenti, Ni Huang, Laura Bergamaschi, Simone Webb, Amada Sanchez-Gonzalez, Jaume Bacardit, Sophie Hambleton, Nusayhah Gopee, Gary Reynolds, Dave Horsfall, Jonathan M. Scott, Aarash Saleh, Nicole Mende, Hamish W King, Karsten Bach, Natsuhiko Kumasaka, Fernando J Calero-Nieto, Vladimir Yu. Kiselev, Sarah A. Teichmann, Sam M. Janes, Rebecca Payne, Kaylee B Worlock, Michael W. Mather, Bayanne Olabi, Muzlifah Haniffa, Rachel A. Botting, A. John Simpson, A Saigal, Angus de Wilton, Menna R. Clatworthy, Katarzyna D. Kania, Paul Coupland, Nicola K. Wilson, Masahiro Yoshida, Chris Duncan, Federica Mescia, Emily Stephenson, Jarmila Stremenova Spegarova, Emma Dann, Ina Schim van der Loeff, Kenneth F Baker, Waradon Sungnak, Elena Prigmore, Jim McGrath, Krzysztof Polanski, Issac Goh, Florian Gothe, Claire Smith, Jonathan Coxhead
The COVID-19 pandemic, caused by SARS coronavirus 2 (SARS-CoV-2), has resulted in excess morbidity and mortality as well as economic decline. To characterise the systemic host immune response to SARS-CoV-2, we performed single-cell RNA-sequencing cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c0b1b468522c0c5b65d5a12538cce0c
https://doi.org/10.1101/2021.01.13.21249725
https://doi.org/10.1101/2021.01.13.21249725
Autor:
Liam A, Hurst, Benjamin J, Dunmore, Lu, Long, Alexi, Crosby, Rafia, Al-Lamki, John, Deighton, Mark, Southwood, Xudong, Yang, Marko Z, Nikolic, Blanca, Herrera, Gareth J, Inman, John R, Bradley, Amer A, Rana, Paul D, Upton, Nicholas W, Morrell
Publikováno v:
Nature Communications
Heterozygous germ-line mutations in the bone morphogenetic protein type-II receptor (BMPR-II) gene underlie heritable pulmonary arterial hypertension (HPAH). Although inflammation promotes PAH, the mechanisms by which inflammation and BMPR-II dysfunc