Zobrazeno 1 - 10
of 172
pro vyhledávání: '"Marko Vendelin"'
Publikováno v:
Bio-Protocol, Vol 14, Iss 16 (2024)
Gel image analyses are often difficult to reproduce, as the most commonly used software, the ImageJ Gels plugin, does not automatically record any steps in the analysis process. This protocol provides detailed steps for image analysis using IOCBIO Ge
Externí odkaz:
https://doaj.org/article/72ab4df5a08144a385ce2e47536e4186
Autor:
Jaak Kütt, Georg Margus, Lauri Kask, Triinu Rätsepso, Kärol Soodla, Romain Bernasconi, Rikke Birkedal, Priit Järv, Martin Laasmaa, Marko Vendelin
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Current solutions for the analysis of Western Blot images lack either transparency and reproducibility or can be tedious to use if one has to ensure the reproducibility of the analysis. Results Here, we present an open-source gel
Externí odkaz:
https://doaj.org/article/7a20e639c19f404a9cffde58d3839d34
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/a18d5bfa7ff748ce9f716d5feda83bf0
Autor:
Robert Risti, Kathryn H Gunn, Kristofer Hiis-Hommuk, Natjan-Naatan Seeba, Hamed Karimi, Ly Villo, Marko Vendelin, Saskia B Neher, Aivar Lõokene
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283358 (2023)
Lipoprotein lipase (LPL), a crucial enzyme in the intravascular hydrolysis of triglyceride-rich lipoproteins, is a potential drug target for the treatment of hypertriglyceridemia. The activity and stability of LPL are influenced by a complex ligand n
Externí odkaz:
https://doaj.org/article/471c224a265c4d6c8a964152aa0edf8f
Autor:
Marko Vendelin, Martin Laasmaa, Mari Kalda, Jelena Branovets, Niina Karro, Karina Barsunova, Rikke Birkedal
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 12, p e1008475 (2020)
Biological measurements frequently involve measuring parameters as a function of time, space, or frequency. Later, during the analysis phase of the study, the researcher splits the recorded data trace into smaller sections, analyzes each section sepa
Externí odkaz:
https://doaj.org/article/7ce235eb8357462f8f54f8b5a5146cdf
Publikováno v:
PeerJ, Vol 7, p e6652 (2019)
Analysis of calcium sparks in cardiomyocytes can provide valuable information about functional changes of calcium handling in health and disease. As a part of the calcium sparks analysis, sparks detection and characterization is necessary. Here, we d
Externí odkaz:
https://doaj.org/article/da966f64235d4131b2ddb1c388f13def
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 377
The ontogeny of the heart describes its development from the fetal to the adult stage. In newborn mammals, blood pressure and thus cardiac performance are relatively low. The cardiomyocytes are thin, and with a central core of mitochondria surrounded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123fe705529129a9bf7e459fb2129f4d
https://doi.org/10.1098/rstb.2021.0321
https://doi.org/10.1098/rstb.2021.0321
Publikováno v:
Analytical Methods. 12:2287-2294
Droplet microfluidic assays are rapidly gaining popularity because they enable analysis of biochemical reactions, individual cells or small cell populations with high sensitivity, precision and accuracy in a high-throughput manner. Nonetheless, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18af8f8c44fa1ebc180f8d62fb9ec79
https://doi.org/10.1039/d0ay00031k
https://doi.org/10.1039/d0ay00031k
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137438 (2015)
The aim of this work is to incorporate cooperativity into Huxley-type cross-bridge model in thermodynamically consistent way. While the Huxley-type models assume that cross-bridges act independently from each other, we take into account that each cro
Externí odkaz:
https://doaj.org/article/858d77c2904944c884db352fb57eaab1
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99413 (2014)
The effective integrated organization of processes in cardiac cells is achieved, in part, by the functional compartmentation of energy transfer processes. Earlier, using permeabilized cardiomyocytes, we demonstrated the existence of tight coupling be
Externí odkaz:
https://doaj.org/article/ef80a385df604aee9302751a388b1a85