Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Marko Marhl"'
Publikováno v:
Interactive Journal of Medical Research, Vol 13, p e55699 (2024)
BackgroundThe interrelation between COVID-19 and various cardiovascular and metabolic disorders has been a critical area of study. There is a growing need to understand how comorbidities such as cardiovascular diseases (CVDs) and metabolic disorders
Externí odkaz:
https://doaj.org/article/7ccc0f6f72c141fe81375a7e66a2b638
Autor:
Rene Markovič, Vladimir Grubelnik, Tadej Završnik, Helena Blažun Vošner, Peter Kokol, Matjaž Perc, Marko Marhl, Matej Završnik, Jernej Završnik
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionType 2 diabetes mellitus (T2DM) is a complex, chronic disease affecting multiple organs with varying symptoms and comorbidities. Profiling patients helps identify those with unfavorable disease progression, allowing for tailored therapy a
Externí odkaz:
https://doaj.org/article/e5eb955c3bb84a07a031eee54ea1536e
Publikováno v:
Results in Physics, Vol 26, Iss , Pp 104433- (2021)
We propose and study an epidemiological model on a social network that takes into account heterogeneity of the population and different vaccination strategies. In particular, we study how the COVID-19 epidemics evolves and how it is contained by diff
Externí odkaz:
https://doaj.org/article/6df84673b53c47a3893b3cca453103ec
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1627 (2022)
Hyperlipidemia is a common metabolic disorder in modern society and may precede hyperglycemia and diabetes by several years. Exactly how disorders of lipid and glucose metabolism are related is still a mystery in many respects. We analyze the effects
Externí odkaz:
https://doaj.org/article/4b7f74105e004ab6afb6566b1c63e7c5
Autor:
Marko Šterk, Lidija Križančić Bombek, Maša Skelin Klemen, Marjan Slak Rupnik, Marko Marhl, Andraž Stožer, Marko Gosak
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1009002 (2021)
NMDA receptors promote repolarization in pancreatic beta cells and thereby reduce glucose-stimulated insulin secretion. Therefore, NMDA receptors are a potential therapeutic target for diabetes. While the mechanism of NMDA receptor inhibition in beta
Externí odkaz:
https://doaj.org/article/c4d94dc678cf4b9688cc8728c090d99a
Autor:
Jan Zmazek, Maša Skelin Klemen, Rene Markovič, Jurij Dolenšek, Marko Marhl, Andraž Stožer, Marko Gosak
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Beta cells within the pancreatic islets of Langerhans respond to stimulation with coherent oscillations of membrane potential and intracellular calcium concentration that presumably drive the pulsatile exocytosis of insulin. Their rhythmic activity i
Externí odkaz:
https://doaj.org/article/64e744cd74a54c4ea00483b0c057a675
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/d4709a5bcb754eac95bd69ba3a80f500
Publikováno v:
Metabolites, Vol 12, Iss 4, p 348 (2022)
Type 2 Diabetes Mellitus (T2DM) is a burdensome problem in modern society, and intensive research is focused on better understanding the underlying cellular mechanisms of hormone secretion for blood glucose regulation. T2DM is a bi-hormonal disease,
Externí odkaz:
https://doaj.org/article/f094070fee2847e7a96eb8d930317a33
Publikováno v:
Frontiers in Materials, Vol 7 (2020)
A precise structural organization of epithelial cells is needed for the proper functioning and development of different tissues. The epithelial cell packing mechanism is associated with mechanical interactions between cells that place the tissue in a
Externí odkaz:
https://doaj.org/article/e296928030bb4f65b2df2c9a85d655ed
Autor:
Vladimir Grubelnik, Rene Markovič, Saška Lipovšek, Gerd Leitinger, Marko Gosak, Jurij Dolenšek, Ismael Valladolid-Acebes, Per-Olof Berggren, Andraž Stožer, Matjaž Perc, Marko Marhl
Publikováno v:
Royal Society Open Science, Vol 7, Iss 1 (2020)
Type 2 diabetes mellitus (T2DM) has been associated with insulin resistance and the failure of β-cells to produce and secrete enough insulin as the disease progresses. However, clinical treatments based solely on insulin secretion and action have ha
Externí odkaz:
https://doaj.org/article/454729f8eaaa4b82a6578669f44af8c2