Výsledky vyhledávání - "Marko Krivec"

Akademický článek

Improved Process for the Synthesis of 3-(3-Trifluoromethylphenyl)propanal for More Sustainable Production of Cinacalcet HCl

Autor: Vikas Damu Rathod, Stefano Paganelli, Marijan Kočevar, Marko Krivec, Oreste Piccolo

Publikováno v: Molecules, Vol 28, Iss 16, p 6042 (2023)

Cinacalcet (I), sold as hydrochloride salt, is a calcimimetic drug which has been approved for the treatment of secondary hyperparathyroidism in patients with chronic renal disease and for the treatment of hypercalcemia in patients with parathyroid c

Externí odkaz: https://doaj.org/article/4cf1b83127ef48c8a034f1d81c2e85d5

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1 H− 15 N HMBC NMR as a tool for rapid identification of isomeric azaindoles: The case of 5F‐MDMB‐P7AICA

Autor: Mojca Janežič, Mateja Mihelač, Miha Virant, Marko Krivec, Damijana Urankar, Bruno Aleksander Martek, Sonja Klemenc, Bojana Koštrun, Martin Gazvoda, Tomaž Gostič, Brigita Nemec, Janez Košmrlj

Publikováno v: Drug Testing and Analysis. 11:617-625

The high frequency of the synthetic cannabinoid receptor agonists (SCRAs) emergence renders this group of new psychoactive compounds particularly demanding in terms of detection, identification, and responding. Without the available reference materia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7464c8e6c6cd6dca95f4a9230d2ceb86
https://doi.org/10.1002/dta.2573

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En Route to 2-(Cyclobuten-1-yl)-3-(trifluoromethyl)-1H-indole

Autor: Marko Krivec, Martin Gazvoda, Janez Košmrlj, Zdenko Časar

Publikováno v: The Journal of Organic Chemistry. 83:2486-2493

A six-step synthetic route from 4-chloro-2-methylaniline to 5-chloro-2-(cyclobut-1-en-1-yl)-3-(trifluoromethyl)-1H-indole (1) has been reported. Compound 1a is a key impurity of reverse transcriptase inhibitor efavirenz, an important anti-HIV/AIDS dr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09a3e2672944066ed4a3b7d7453a9de
https://doi.org/10.1021/acs.joc.8b00100

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Regioselective Hydrolysis and Transesterification of Dimethyl 3-Benzamidophthalates Assisted by a Neighboring Amide Group

Autor: Janez Košmrlj, Franc Perdih, Marko Krivec, Marijan Kočevar

Publikováno v: The Journal of Organic Chemistry. 81:5732-5739

An efficient, highly regioselective hydrolysis and transesterification of dimethyl 3-benzamidophthalates into the corresponding carboxylic acid monoesters and mixed esters (including tert-butyl esters) under basic conditions is presented. The selecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92db424b468733910f2c9966544aacae
https://doi.org/10.1021/acs.joc.6b00765

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Chloranil as an Efficient Oxidant of the Cyclohexadiene Intermediates Formed by a Cycloaddition of Substituted 2H-Pyran-2-ones and Styrenes En Route to the Boscalid Derivatives

Autor: Jasmin Suljagić, Marko Krivec, Kristof Kranjc, Marijan Kočevar, Amadej Juranovič

Publikováno v: Journal of Heterocyclic Chemistry. 54:457-464

We describe a three-step one-pot metal-free domino procedure yielding a set of boscalid derivatives, parent compound being a highly important agrochemical agent. The first step of the process consists of the Diels–Alder reaction between a substitut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d2e989c22c56ce5bc2e0655524346d5e
https://doi.org/10.1002/jhet.2603

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Seasonal and spatial variations in the occurrence, mass loadings and removal of compounds of emerging concern in the Slovene aqueous environment and environmental risk assessment

Autor: Marjeta Česen, Janez Košmrlj, Ester Heath, David Heath, Tina Kosjek, Marko Krivec

Publikováno v: Environmental pollution (Barking, Essex : 1987). 242

This study reports the development of a multi-residue method for determining 48 compounds of emerging concern (CEC) including three diclofenac transformation products (TP) in Slovenian wastewater (WW) and surface water (SW). For solid-phase extractio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1057fb99820431b7a7720a5835b83c81
https://pubmed.ncbi.nlm.nih.gov/29966838

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ChemInform Abstract: Regioselective Hydrolysis and Transesterification of Dimethyl 3-Benzamidophthalates Assisted by a Neighboring Amide Group

Autor: Marijan Kočevar, Janez Košmrlj, Franc Perdih, Marko Krivec

Publikováno v: ChemInform. 47

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2e7e7d7f51c7ca94082ca8bad4e1ea87
https://doi.org/10.1002/chin.201647082

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ChemInform Abstract: A Way to Avoid Using Precious Metals: The Application of High-Surface Activated Carbon for the Synthesis of Isoindoles via the Diels-Alder Reaction of 2H-Pyran-2-ones

Autor: Slovenko Polanc, Marijan Kočevar, Kristof Kranjc, Marko Krivec, Martin Gazvoda

Publikováno v: ChemInform. 43

The application of activated carbon (Darco KB) for the acceleration and direction of the transformation of various 2H-pyran-2-ones with N-substituted maleimides toward isoindole derivatives through the reaction sequence cycloaddition/elimination/dehy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e2e0639af308972d31b9b4c72c836aea
https://doi.org/10.1002/chin.201228125

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