Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Marko Kosicek"'
Autor:
Marko Kosicek, Silva Hecimovic
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 1, Pp 1310-1322 (2013)
Brain is one of the richest organs in lipid content. Phospholipids (glycerophospholipids and sphingolipids) are important building blocks of cell membranes, which provide an optimal environment for protein interactions, trafficking and function. Beca
Externí odkaz:
https://doaj.org/article/da352e21649f48ed8fbe8cb1ba5a61be
Autor:
Bjoern von Einem, Petra Weber, Michael Wagner, Martina Malnar, Marko Kosicek, Silva Hecimovic, Christine A. F. von Arnim, Herbert Schneckenburger
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 12, Pp 15801-15812 (2012)
Förster resonance energy transfer (FRET) -based techniques have recently been applied to study the interactions between β-site APP-cleaving enzyme-GFP (BACE1-GFP) and amyloid precursor protein-mRFP (APP-mRFP) in U373 glioblastoma cells. In this con
Externí odkaz:
https://doaj.org/article/4514826677c544ceb9866a6349144f07
Autor:
Stjepko Cermak, Marko Kosicek, Aleksandra Mladenovic-Djordjevic, Kosara Smiljanic, Selma Kanazir, Silva Hecimovic
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167428 (2016)
Proper function of lysosomes is particularly important in neurons, as they cannot dilute accumulated toxic molecules and aggregates by cell division. Thus, impairment of lysosomal function plays an important role in neuronal degeneration and in the p
Externí odkaz:
https://doaj.org/article/5bb369c424eb4e27bb3ac841b1235402
Publikováno v:
Interdisciplinary Description of Complex Systems, Vol 21, Iss 3, Pp 297-308 (2023)
There has long been a struggle over how to increase student interest in careers in STEM and meet the labour market’s need for specialised knowledge and skills. The long-standing debate at the EU level about the role of formal, informal, and non-for
Externí odkaz:
https://doaj.org/article/9d46c9f2fc4d48d986fe8486f7577afc
Autor:
Ivan Gudelj, Marko Kosicek, Anita Horvatić, Silva Hećimović, Tanja Jovic, Gordan Lauc, Frano Vučković
Publikováno v:
Molecular & cellular proteomics
Molecular & Cellular Proteomics
Molecular & Cellular Proteomics
Increasing evidence implicates lysosomal dysfunction in the pathogenesis of neurodegenerative diseases, including the rare inherited lysosomal storage disorders (LSDs) and the most common neurodegenerative diseases, such as Alzheimer's and Parkinson'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934d6b2c9f3a0bdab0ba862deaec8c8d
Autor:
Jasminka Stefulj, Cornelia Schweinzer, Monika Scholler, Maja Perić, Marko Kosicek, Jelena Zivkovic, Martina Malnar, Silva Hećimović, Ute Panzenboeck
Publikováno v:
Current Pharmaceutical Biotechnology. 14:582-593
Niemann-Pick type C disease (NPC) is an inherited disorder mainly caused by loss-of-function mutations in the NPC1 gene, that lead to intracellular cholesterol accumulation and disturbed cholesterol homeostasis. Similarly to Alzheimer's disease (AD),
Autor:
Maria Blomqvist, Caroline A. Hastings, Erik Portelius, Ulf Andreasson, Johan Gobom, Marko Kosicek, Niklas Mattsson, Mikael K. Gustavsson, Maria Olsson, Silva Hećimović, Kaj Blennow, Charles H. Vite, Martina Malnar, Gunnar Brinkmalm, Henrik Zetterberg, Jan-Eric Månsson
Publikováno v:
Metabolic Brain Disease. 27:573-585
Niemann-Pick type C (NPC) is a progressive neurodegenerative lysosomal disease with altered cellular lipid trafficking. The metabolism of amyloid-β (Aβ) - previously mainly studied in Alzheimer's disease - has been suggested to be altered in NPC. H
Publikováno v:
Biochemical and biophysical research communications. 450(1)
Alzheimer’s disease (AD) and a rare inherited disorder of cholesterol transport, Niemann-Pick type C (NPC) share several similarities including aberrant APP processing and increased Aβ production. Previously, we have shown that the AD-like phenoty
Autor:
Silva Hećimović, Marko Kosicek
Publikováno v:
International Journal of Molecular Sciences
Brain is one of the richest organs in lipid content. Phospholipids (glycerophospholipids and sphingolipids) are important building blocks of cell membranes, which provide an optimal environment for protein interactions, trafficking and function. Beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b52abebbf03a5ef452fa7d2e43e0ab05
https://www.bib.irb.hr/629646
https://www.bib.irb.hr/629646
Autor:
Martina, Malnar, Marko, Kosicek, Raphael, Bene, Iva Petek, Tarnik, Sanda, Pavelin, Ivana, Babic, Bojana, Brajenovic-Milic, Hrvoje, Hecimovic, Marina, Titlic, Zlatko, Trkanjec, Ida, Demarin, Silva, Hecimovic
Publikováno v:
Acta neurobiologiae experimentalis. 72(3)
Low levels of amyloid-beta42 (Abeta42) and high total-tau (t-tau) or phosphorylated-tau (p181-tau) levels in cerebrospinal fluid (CSF) were shown to be characteristic for Alzheimer's disease (AD) patients and for mildly cognitively impaired (MCI) or