Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Marko, Kaleva"'
Autor:
Ida Maria Schmidt, Anne-Maarit Haavisto, Ida N. Damggard, Heqing Shen, Niels E. Skakkebæk, Karl-Werner Schramm, Helena E. Virtanen, Katharina M. Main, Marla Chellakooty, Kirsten A Boisen, Jorma Toppari, Marko Kaleva
Publikováno v:
Chemosphere. 67:S256-S262
The exposure levels of placenta and paired breast milk samples to selected organochlorine compounds and pesticides from Danish and Finnish samples have been investigated. p , p ′-DDE is the dominant pollutant, β-HCH, hexachlorobenzene, endosulfan-
Autor:
Katharina M. Main, Marko Kaleva, Niels E. Skakkebæk, Karl-Werner Schramm, Helena E. Virtanen, Heqing Shen, Jorma Toppari, Anna-Maria Andersson
Publikováno v:
Chemosphere. 62:390-395
The enantiomeric ratios (ER) of α-HCH and o , p ′-DDT ((+)-isomer concentration/(−)-isomer concentration) and o , p ′-DDD (first eluting enantiomer/second enantiomer) were investigated in 112 human placentas from Finnish boys collected 1997–
Autor:
Ida N. Damgaard, Niels E. Skakkebæk, Ida Maria Schmidt, Marla Chellakooty, Helena E. Virtanen, Claudia Mau Kai, Jorma Toppari, Anne-Maarit Suomi, Katharina M. Main, Marko Kaleva, Kirsten A Boisen, Malene Boas
Publikováno v:
European Journal of Endocrinology. 154:125-129
Objective: Infant boys show a brief activation of their hypothalamic–pituitary–gonadal axis shortly after birth, the physiological significance of which is poorly understood. The objective of the study was to investigate the correlation between e
Autor:
Jorma Toppari, Helena E. Virtanen, Ilpo Huhtaniemi, Katharina M. Main, Kerttu Irjala, Niels E. Skakkebæk, Anne-Maarit Haavisto, Marko Kaleva
Publikováno v:
Pediatric Research. 58:447-450
Undescended testes are a common urogenital malformation affecting 2-9% of newborn boys. The etiology of cryptorchidism is probably heterogeneous, but insufficient androgen effect has been recognized as one cause of the condition. A common genetic var
Autor:
Jorma Toppari, Marko Kaleva
Publikováno v:
Cell and Tissue Research. 322:167-172
Cryptorchidism is a common ailment of new-born boys, affecting 1-9% of full term boys at birth. Cryptorchidism has been associated with an increased risk of testicular cancer and reduced fertility. Aetiology of cryptorchidism remains obscure in most
Autor:
Jorma Toppari, Marko Kaleva
Publikováno v:
HORMONES. 2:211-216
Testicular descent is an essential part of normal male sexual development. Any anomaly that disrupts normal testicular descent will be clinically evident as cryptorchidism. Several factors, such as Hoxa-10, epidermal growth factor (EGF), calcitonin g
Publikováno v:
APMIS. 109:S37-S42
Cryptorchidism and hypospadias share possible risk factors, such as intrauterine growth retardation. According to the data collected by the International Clearinghouse for Birth Defects Monitoring Systems (ICBDMS), apparently increasing trends in the
Autor:
Matti Poutanen, Marko Kaleva, Pasi Koskimies, Ilpo Huhtaniemi, Helena E. Virtanen, Jorma Toppari, Magdalena Lindström
Publikováno v:
Pediatric Research. 47:538-541
The incidence of impaired testicular descent (cryptorchidism) is high; 1-2% of boys at the age of 3 mo are diagnosed for this condition in western countries. Recent data on mice with targeted disruption of the Insl3/relaxin-like factor (RLF) gene pro
Autor:
Martti Parvinen, Fu-Ping Zhang, Marko Kaleva, Wei Yan, Jorma Toppari, Molle Söder, Patricia L. Morris, Katariina Vänttinen, Harri Hakovirta
Publikováno v:
Endocrinology. 140:1492-1498
To address the possibility that stem cell factor (SCF) is a paracrine regulator of germ cell development in the adult rat testis, stage-specific distribution of SCF messenger RNA (mRNA) was investigated with Northern blot and in situ hybridization an
Autor:
Pirjetta Heiskanen, Ali Arsalo, Håkan Billig, Leo Dunkel, Juhani Rapola, Marko Kaleva, Jorma Toppari
Publikováno v:
Pediatric Research. 40:351-356
Cryptorchidism is associated with histologic changes in the human testis apparent by 2 y of age. The mechanism accounting for these changes is still unknown. To clarify whether apoptosis plays a role in human cryptorchidism, we evaluated its occurren